Impact of a DASH diet on kidney stone risk factors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate how a DASH-style diet influences urinary risk factors associated with kidney stone disease. Participants diagnosed with kidney stones will be randomized to follow either a DASH-style diet or a Western-style diet for one week, with all meals provided by the Bionutrition Unit. The primary goal is to measure changes in 24-hour urine stone risk parameters, establishing a benchmark for future dietary interventions in kidney stone prevention. This is the first controlled study specifically assessing the DASH dietary pattern in this context.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Birmingham, AL area participants of the Coronary Artery Risk Development in Young Adults (CARDIA) study OR patients of the University of Alabama at Birmingham/Kirklin Clinic
* Self-reported, documented, and/or prior imaging-based diagnosis of kidney stone disease
* Age 19-89
* Any sex
* Any race
* Able to provide informed consent
* Willing to perform 24-hour urine collections
* Willing to consume meals prepared by Bionutrition Unit
* No food allergies/intolerance to any of the foods in the study menus
* Willing to stop for 7 days before and during study: Multivitamins and/or Dietary supplements (including calcium and vitamin C)

Exclusion Criteria:

* Dialysis
* Kidney transplant recipient
* Estimated glomerular filtration rate (eGFR) \<60 ml/min/1.73m2 based on historical laboratory measurements
* Renal tubular acidosis
* Current use of acetazolamide, topiramate, or zonisamide
* Primary hyperparathyroidism or history of parathyroidectomy
* Hyperthyroidism
* Sarcoidosis
* Primary hyperoxaluria
* Cystinuria
* Nephrotic syndrome
* Malabsorptive conditions including inflammatory bowel disease or history of malabsorptive surgery (e.g., Roux-en-Y gastric bypass, small bowel resection)
* Urinary retention requiring catheterization
* Urinary diversion
* Pregnancy
* Breastfeeding
* Malignancy treated in the past 12 months other than non-melanoma skin cancer

Where it's running

• University of Alabama at Birmingham
  Birmingham, Alabama, United States Recruiting

Study contacts

• Study coordinator: Joseph Crivelli, MD
• Email: crivelli@uab.edu
• Phone: 205-996-8765

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Emergency urinary drainage followed by PCNL in obstructive urosepsis

  Doctors test whether the method of emergency drainage (retrograde ureteral stent or percutaneous nephrostomy) affects how well patients do after undergoing definitive PCNL.

  Recruiting Beni-Suef University · Banī Suwayf, Beni Suweif Governorate · NCT07826325

• Observation vs Upfront Surgery for Asymptomatic Kidney Stones in Children and Adults

  This trial tests whether watching asymptomatic kidney stones or performing upfront surgery is better for reducing life disruption in patients aged 6 and older.

  Recruiting at 2 sites Children's Hospital of Philadelphia · Irvine, California and 3 other locations · NCT07718802

• Two-Tier Virtual Reality Education to Reduce Anxiety Before Kidney Stone Surgery

  This study tests whether a two-tier VR preoperative education approach can lower anxiety and improve knowledge and self-care in adults undergoing urolithiasis surgery.

  Recruiting Chang Gung Memorial Hospital · Keelung · NCT07620873

• Tamsulosin 0.4 mg with Tadalafil 5 mg versus 2.5 mg to reduce symptoms from ureteral stents

  This will test whether adding Tadalafil at 5 mg or 2.5 mg to Tamsulosin 0.4 mg better reduces stent-related symptoms for adults with a double-J ureteral stent after stone removal.

  Recruiting Ain Shams University · Cairo, Abbasia · NCT07562282

• Ureteral access sheath: omitting versus placing a stent after ureteroscopy

  We will test if leaving out a ureteral stent after ureteroscopy with an access sheath works as well as placing a stent for pre-stented adults with kidney or ureteral stones.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07297953

• Using a flexible suction sheath with flexible ureteroscopy for lower-pole kidney stones

  This trial will test whether adding a flexible, navigable suction sheath to flexible ureteroscopy helps adults with lower-pole kidney stones become stone-free more often and avoid repeat procedures.

  Recruiting Zagazig University · Zagazig · NCT07238803

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.