Understanding brain emotion processing in epilepsy patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research aims to explore how emotion processing occurs in the brain by utilizing stereoelectroencephalography (sEEG) and direct brain stimulation. The study will involve behavioral tasks related to emotion processing while recording neural activity and applying stimulation pulses to assess their effects. By analyzing the data collected from the electrodes during these tasks, the researchers hope to identify disruptions in the fronto-limbic network that contribute to emotional regulation issues in individuals with epilepsy and comorbid mental health disorders. The ultimate goal is to develop targeted brain modulation protocols for improved treatment outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 1\) implantation of sEEG electrodes for SOC epilepsy surgery evaluation
* 2\) cognitive ability to perform simple tasks and to understand instructions
* 3\) implanted electrodes in the amygdala and medial PFC regions
* 4\) competency to understand and sign a written informed consent.

Exclusion Criteria:

* 1\) an inability to complete the task

Where it's running

• Epilepsy Monitoring Unit UAB Hospital
  Birmingham, Alabama, United States Recruiting

Study contacts

• Principal investigator: Adam Goodman, PhD — University of Alabama at Birmingham
• Study coordinator: Rebekah Chatfield, BS
• Email: joyb3@uab.edu
• Phone: (205) 975-3477

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.