Peer-led PrEP delivery for youth in Brazil: a youth-focused PrEP access trial
Official title: Determining the impact of peer-led, community-based PrEP delivery among youth in Brazil: A randomized controlled trial
Funded at University of Alabama at Birmingham · NIH-11528255 · Data updated 2026-11-12
This project tests whether trained youth peer workers can deliver PrEP in community settings to increase PrEP uptake among young people in Brazil.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project start | July 19, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $202,718 |
| NIH project number | 3R01MH135769-03S1 |
| Project ID | NIH-11528255 on NIH RePORTER |
Who could benefit from this research
✓Could help
Youth aged roughly 13-24 who are at risk for HIV and may benefit from PrEP in Brazil.
✕Less likely to help
Youth not at risk for HIV or not considering PrEP may not experience direct benefit.
What this research studies
The study builds on prior work showing peers improve engagement with HIV services. It tests a model where trained peer youth workers deliver PrEP in community venues rather than traditional clinics, with a randomized design to measure uptake and adherence. The goal is to understand how to make PrEP more accessible and acceptable for youth in Brazil, and to inform scalable approaches.
Why it matters
Potential benefit: If successful, it could lead to more youth getting PrEP quickly and staying on PrEP, reducing new HIV infections.
How similar studies have gone: Prior adolescent PrEP work (PrEP1519) showed peers can aid engagement, suggesting potential for success with this approach.
Where this research is happening
-
University of Alabama at Birmingham
Birmingham, United States Active
Researchers
- Principal investigator: Bruxvoort, Katia — University of Alabama at Birmingham
- Study coordinator: Bruxvoort, Katia
Related research
Other NIH-funded projects on the same topics.
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A brief alcohol support for PrEP users to boost HIV prevention
A short, friendly program helps people starting or restarting PrEP in Vietnam drink less and stick with PrEP to stay protected.
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Peer-led PrEP delivery for youth in Brazil: a community-based randomized trial
A youth-focused, community-based program tests whether trained young peers can help more adolescents get HIV PrEP in Brazil.
-
Peer-led PrEP delivery for youth in Brazil: a trial to boost PrEP uptake
A youth-focused program tests whether trained young peers delivering PrEP in community settings can help more teens in Brazil start and stay on PrEP.
-
Brief alcohol help to improve PrEP use in Vietnam
A short, friendly program helps people starting or restarting PrEP in Vietnam to drink less and stick with PrEP to prevent HIV.
-
Helping people on PrEP reduce drinking and stay on HIV prevention
A short counseling program using motivational interviewing and CBT aims to help people on PrEP who drink at risky levels cut back and keep taking their HIV prevention medicine.
-
W-PrEP: clinic-level steps to help women get PrEP for HIV prevention
A clinic-level program helps healthcare teams better offer and support PrEP for women to prevent HIV.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.