PrEP Optimization Through Enhanced Continuum Tracking (PrOTECT AL)
Official title: PrOTECT AL: PrEP Optimization Through Enhanced Continuum Tracking
Run by University of Alabama at Birmingham · NCT07231640 · Data updated 2026-11-12
This project will test a real-time PrEP care dashboard and implementation strategies at seven Alabama clinics to see if they increase PrEP coverage and equity among people at risk for HIV.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 56 (estimated) |
| Sponsor | University of Alabama at Birmingham Academic / other |
| Locations | 1 site (Birmingham, Alabama) |
| Status | Recruiting |
| Started | February 9, 2026 |
| Main results expected | January 2030 |
| Study ends | April 2030 |
| Registry record updated | February 20, 2026 |
| Trial ID | NCT07231640 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal participants are English-speaking clinic staff aged 18 or older (providers, nurses/medical assistants, clinical administrators, or data managers) who work at one of the seven participating Alabama PrEP clinics.
✕Probably not a fit
Individuals who are not staff at the seven participating sites, who are under 18, or who do not speak English are not eligible and are unlikely to benefit directly from this implementation effort.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
PrOTECT AL implements a real-time PrEP Care Continuum dashboard across seven clinics in Alabama, using data mapping and quarterly STI overlap to visualize service-area PrEP coverage and equity. The team will refine the dashboard, perform on-site organizational readiness assessments, and incorporate clinic-specific PrEP equity performance indexes. Implementation outcomes guided by the RE-AIM framework (including reach, adoption, and maintenance) will be measured at each site, with a primary outcome comparing changes in PrEP prescriptions to Black versus White persons with PrEP indications. Effectiveness will be tested using an interrupted time-series analysis of the PrEP-to-need ratio and overall PrEP coverage.
Why it matters
Potential benefit: If successful, the dashboard and implementation strategies could help clinics identify and close PrEP coverage gaps and increase equitable PrEP prescribing to reduce HIV risk in underserved populations.
How similar studies have gone: Similar data-driven dashboard and implementation interventions for HIV prevention and PrEP have shown promising improvements in care metrics at single-site or regional programs, although multi-site controlled implementations remain limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * currently practicing providers (either a clinician, nurse or medical assistant), OR 2) clinical administrator (e.g., someone in a leadership role within the PrEP clinic), OR 3) a data manager (i.e., someone who collects, enters and or manages data within the clinic) AND * English speaking * Age ≥ 18. Exclusion Criteria: * Not one of the seven participating sites
Where it's running
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University of Alabama at Birmingham
Birmingham, Alabama, United States Recruiting
Study contacts
- Principal investigator: Michael Mugavero, MD — University of Alabama at Birmingham
- Study coordinator: Mariel Parman, MPH
- Email: marielparman@uabmc.edu
- Phone: 205-996-6337
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.