Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Using Acceptance and Commitment Therapy to help religious OCD

Official title: Efficacy of Acceptance and Commitment Therapy on Religiously Oriented Obsessive-Compulsive Disorder

Run by University of Alabama at Birmingham · NCT06647589 · Data updated 2026-11-12

This project will try Acceptance and Commitment Therapy (ACT) to see if it helps adults with religiously focused OCD.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment10 (estimated)
SponsorUniversity of Alabama at Birmingham
Academic / other
Locations1 site (Birmingham, Alabama)
StatusRecruiting
StartedJuly 30, 2025
Main results expectedMarch 1, 2027
Study endsMarch 1, 2027
Registry record updatedSeptember 28, 2026
Trial IDNCT06647589 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults (18+) with clinically significant scrupulosity who can attend in-person sessions and do not have recent psychosis, active suicidal intent, recent narcotics use, or recent self-harm or eating-disorder behaviors.

Probably not a fit

People with recent psychosis, current suicidal or homicidal intent, recent non-suicidal self-injury, recent narcotics use, or recent purging/restricting may be excluded and are unlikely to benefit from this intervention.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults (18+) who meet a scrupulosity cutoff will receive Acceptance and Commitment Therapy delivered at the University of Alabama at Birmingham in a single-site, open-label intervention. The study will measure changes in religious OCD symptom severity, feasibility outcomes, and safety using standard symptom scales and clinical interviews. People with recent psychosis, active suicidal intent, recent non-suicidal self-injury, recent narcotics use, or recent purging/restricting behaviors are excluded. The aim is to see whether ACT techniques for acceptance, mindfulness, and values-based action reduce distress and compulsive rituals tied to religious obsessions.

Why it matters

Potential benefit: If successful, ACT could reduce distress and compulsive behaviors tied to religious obsessions and offer a non-medication psychotherapy option.

How similar studies have gone: ACT has shown promise in prior research for OCD and related anxiety disorders, but targeted evidence specifically for scrupulosity is limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18 years old
* Meet cutoff scores for scrupulosity

Exclusion Criteria:

* Presence of psychotic symptoms within six months of screening
* Current suicidal/homicidal plan/intent and/or a suicide/homicide attempt within 6 months of screening
* Non-suicidal self-injury within 6 months of screening
* Narcotics use within 3 months of screening
* Purging/restricting behavior within 3 months of screening.

Where it's running

  • University of Alabama at Birmingham
    Birmingham, Alabama, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.