Cognitive training for preterm infants using finger puppets

Infant-Maternal Partnership and Cognitive Training Study for Preterm Infants: A Randomized Clinical Trial

Not applicable Interventional University of Alabama at Birmingham · NCT06335524

This study is testing if using finger puppets in caregiver interactions can help preterm infants develop better communication skills compared to regular care.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment188 (estimated)
Ages1 Week to 17 Weeks
SexAll
SponsorUniversity of Alabama at Birmingham Academic / other
Locations1 site (Birmingham, Alabama)
Trial IDNCT06335524 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of a caregiver-implemented early developmental intervention (EDI) that utilizes finger puppets to enhance joint attention and interactive communication in preterm infants. The intervention will be compared to routine EDI care that includes Bookworm training alone. The primary outcome measure will be the Ages and Stages Questionnaire® score at 12 months corrected age, assessing the developmental progress of the infants. The study focuses on infants born at less than 34 weeks' gestation who are off sedatives and invasive respiratory support.

Who should consider this trial

Good fit: Ideal candidates for this study are preterm infants born at less than 34 weeks' gestation who are currently off sedatives and invasive respiratory support.

Not a fit: Patients with major malformations or known syndromes, or those enrolled in competing trials targeting neurodevelopmental outcomes, may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve cognitive and developmental outcomes for preterm infants.

How similar studies have performed: Other studies have shown promising results with similar caregiver-implemented interventions for preterm infants, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* inborn at UAB, delivered at less than 34 weeks' gestation, 32-39 weeks' PMA, off sedatives, and off invasive respiratory support.

Exclusion Criteria:

* a major malformation, a known syndrome, enrolled in a competing trial targeting neurodevelopmental outcomes as a primary outcome.

Where this trial is running

Birmingham, Alabama

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Child DevelopmentInfant DevelopmentInfant, Premature, Diseases
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.