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Clinical trials and research at Johns Hopkins University

• 241Clinical trials
• 2997NIH research projects
• 2New in 30 days
• 22Countries

Newest trials

All recruiting trials (newest 150 of 241)

• Psilocybin-assisted therapy to help adults with amblyopia see more clearly

  This study tests whether a single or small doses of psilocybin can boost the effectiveness of amblyopia treatment in adults.

  Recruiting Phase 1/2 Johns Hopkins University · Baltimore, Maryland · NCT07920081

• ReVIVE for mTBI: Using VR and therapy to help adults with mild traumatic brain injury

  This study tests a virtual reality therapy combined with standard psychotherapy to see if it can reduce PTSD symptoms and improve executive function in adults with mild traumatic brain injury.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT07890337

• Social Connection Collective for older adults in subsidized housing

  A resident-led program in subsidized housing in Baltimore will try to build friendships and peer support among residents aged 62 and older to see if it’s feasible and if it reduces loneliness.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07863583

• Oral Food Challenge After Starting Omalizumab in Food Allergy

  This trial tests whether omalizumab begins to help with food allergy within 2 to 4 weeks after starting treatment in people with a confirmed food allergy.

  Recruiting Phase 4 Johns Hopkins University · Baltimore, Maryland · NCT07845552

• Imaging markers for bulbar involvement in inclusion body myositis among IBM and comparison groups

  This study tests whether ultrasound and MRI can detect swallowing and bulbar muscle problems in people with inclusion body myositis.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07823101

• Impact of Patient Position on EndoFLIP Measurements in Kids and Young Adults

  This study tests whether EndoFLIP measurements differ when patients are in the supine versus left-side position during the procedure.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07780981

• Augmented reality CPR feedback for pediatric resuscitation

  This study tests whether AR-CPR feedback can help healthcare teams deliver high-quality chest compressions in simulated pediatric cardiac arrest, as compared with coaching from a CPR expert.

  Recruiting at 8 sites Johns Hopkins University · St. Petersburg, Florida and 7 other locations · NCT07778823

• Presymptomatic Epidiolex for Sturge-Weber Syndrome

  This study tests whether cannabidiol (Epidiolex) started in babies with Sturge-Weber syndrome can delay the first seizure.

  Recruiting Phase 2 Johns Hopkins University · Baltimore, Maryland · NCT07778810

• Tirzepatide for Active Central Centrifugal Cicatricial Alopecia (CCCA)

  This pilot test will see if weekly tirzepatide can help adults with active CCCA regrow hair and reduce scarring.

  Recruiting at 2 sites Phase 2 Johns Hopkins University · Baltimore, Maryland and 1 other locations · NCT07734870

• Transventricular Off-pump Mitral Valve Repair for Degenerative Mitral Regurgitation

  This study tests a minimally invasive procedure to repair the mitral valve in adults with severe degenerative mitral regurgitation to see if it is safe and effective.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07726173

• BabaCare: Testing a Care Copilot for lonely older adults

  A new AI voice and text companion called Baba is being tested to see if it can help reduce loneliness and improve mood in older adults who live alone.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07689526

• How long-acting cabotegravir works for HIV prevention and how hormones might affect it

  This study tests whether long-acting cabotegravir can prevent HIV and how endogenous or therapeutic hormones might change its levels in blood and genital tissues among adults.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT07672717

• Liver Transplant from HIV+ Donors: See if HIV+ Recipients Do as Well

  This study tests whether recipients with HIV who get livers from HIV-positive donors can do as well as those who get livers from HIV-negative donors, with focus on infections and cancer after transplant.

  Recruiting at 2 sites Johns Hopkins University · Phoenix, Arizona and 18 other locations · NCT07665372

• Multimodal Glucose Prediction for Type 2 Diabetes

  This study tests whether a multi-modal model that combines CGM data with patient behaviors can better predict glucose levels for adults with type 2 diabetes using mobile apps and wearable devices.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07633171

• Psilocybin with or without Pimavanserin Pretreatment in Healthy Adults

  This study tests whether a single 25 mg dose of psilocybin, given with or without pimavanserin pretreatment or placebo, affects mood and well-being in healthy adults over one month.

  Recruiting Phase 1/2 Johns Hopkins University · Baltimore, Maryland · NCT07610135

• Hemp-based CBD topical lotion pharmacokinetics in healthy adults

  This study tests how a high‑CBD, low‑THC hemp lotion behaves in the body after short‑ and longer‑term use in healthy adults.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT07603518

• Psilocybin With 5-HT1A Blockade in Healthy Volunteers

  This study will test whether blocking the 5-HT1A receptor changes the immediate subjective effects of psilocybin in healthy adults, and also explore how psilocybin affects sleep and dreaming afterward.

  Recruiting Early Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT07565493

• Risk-informed shared-decision making to help people with prediabetes prevent diabetes

  This study tests whether a risk-informed shared decision-making visit or a plain patient portal message can help adults with prediabetes take steps to prevent diabetes.

  Recruiting Johns Hopkins University · Frederick, Maryland · NCT07553325

• Implanted brain interface to let people with severe paralysis control assistive devices

  It will try an implanted brain interface that records and stimulates brain signals so adults with severe paralysis can control assistive devices and receive sensory feedback.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07521930

• GLP-1 receptor agonist NLY01 to slow brain and retinal atrophy in multiple sclerosis

  This trial will test whether the drug NLY01 can slow brain and retinal shrinkage in adults (18–60) with clinically stable multiple sclerosis who have a BMI of 27 or higher.

  Recruiting at 3 sites Phase 2 Johns Hopkins University · Kansas City, Kansas and 2 other locations · NCT07497399

• Corrie Lipids program to help lower high LDL cholesterol

  This program tests whether a smartphone app combined with clinician education and coaching can help adults with uncontrolled LDL-C and high cardiovascular risk reach their cholesterol goals.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07478887

• Impact of a Low-Sodium Salt Substitute on Potassium in Hypertension

  This study tests whether using a low-sodium salt substitute in adults with hypertension on medication can raise or lower potassium levels safely.

  Recruiting Johns Hopkins University · Dhaka · NCT07460882

• e-ALIGN: Using the patient portal to align medicines with what matters most

  This project will see if sending education through the patient portal plus pharmacist-led medication reviews helps people 65 and older with mild cognitive impairment or dementia and their care partners reduce risky brain-active medicines.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07454824

• Optic Nerve Strain in Non-glaucoma Eyes

  This study tests how optic nerve strain responds to lowered eye pressure in people without glaucoma to compare with those who have glaucoma.

  Recruiting Early Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT07425535

• Group postpartum and well-child care for mothers and babies

  We will test whether group postpartum and well-child care for new mothers and their babies in Zomba District, Malawi leads to better maternal and infant health over the first year after birth compared with usual individual care.

  Recruiting at 8 sites Johns Hopkins University · Zomba and 15 other locations · NCT07414901

• Peer support for liver transplant recipients with a history of alcohol use disorder

  This study tests whether having a peer support specialist helps liver transplant recipients with prior alcohol use disorder stay abstinent and stay engaged in care.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07397598

• Food support plus one-on-one behavioral weight-loss program for adults with obesity and food insecurity

  This trial will test whether adding home-delivered groceries or grocery vouchers to a one-on-one behavioral weight-loss program helps adults with obesity who face food insecurity lose more weight.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07396805

• Switching to ublituximab for ocrelizumab wearing-off in multiple sclerosis

  This pilot will try switching people with relapsing MS who experience symptom 'wearing off' on ocrelizumab to ublituximab to see if their symptoms improve or return later.

  Recruiting Phase 4 Johns Hopkins University · Baltimore, Maryland · NCT07389590

• AI-enabled digital stethoscope to guide antibiotic use in young children with pneumonia

  This trial tests whether using an AI-assisted digital stethoscope to guide antibiotic decisions in children with suspected non-severe pneumonia is no worse than standard care at treating them with antibiotics.

  Recruiting Phase 4 Johns Hopkins University · Sylhet · NCT07362433

• One-time double dose of Descovy (F/TAF) in healthy adults

  We will test a one-time double dose of two F/TAF (Descovy) tablets in healthy adults to see how long drug levels remain over 14 days for HIV PrEP.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT07349758

• VR-enhanced progressive muscle relaxation for chronic symptoms after burn injury

  This will try progressive muscle relaxation with and without virtual reality to see if it helps adult burn survivors reduce chronic pain, itch, anxiety, sleep problems, or fatigue.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07317271

• Robot-assisted prostate biopsy using a new ultrasound probe

  This trial will try a robot-guided ultrasound probe to take MRI-fused prostate biopsies in men 40–75 with elevated PSA, abnormal rectal exam, or prior atypical biopsy findings.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT07271017

• Vibrotactile balance belt to improve walking

  This trial will test a vibrating balance belt to see if it improves walking and stability in adults with vestibular problems, ataxia, or other gait disorders.

  Recruiting at 2 sites Johns Hopkins University · Baltimore, Maryland and 1 other locations · NCT07253532

• Isturisa treatment for people with mild autonomous cortisol secretion (MACS)

  This trial will test whether Isturisa (osilodrostat) helps adults with MACS improve metabolic measures, blood pressure, weight, bone density, and quality of life.

  Recruiting Phase 4 Johns Hopkins University · Baltimore, Maryland · NCT07247058

• Strength and Pain-Coping Through Resilience and Knowledge for Older Adults

  The SPARK program tests a home-based, nurse-delivered intervention to help adults 50 and older with pain, depressive symptoms, and mobility limits see if their pain and mood improve.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07228520

• Steroid injections after dilation to help with idiopathic subglottic stenosis

  This trial tests whether injecting steroid at the stenosis after dilation can delay the need for more dilations in adults with idiopathic subglottic stenosis.

  Recruiting at 6 sites Phase 3 Johns Hopkins University · San Diego, California and 9 other locations · NCT07228104

• Being Safe, Healthy, and Positively Empowered (BSHAPE) for foreign-born women

  This project will test a trauma-informed digital program (BSHAPE) to see if it improves safety, mental health, and related health risks for foreign-born immigrant women with histories of violence and PTSD or depression.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07227337

• Home IV fluid infusions after radical cystectomy

  This trial will test whether giving home IV fluids after radical cystectomy for bladder cancer reduces 90-day hospital readmissions.

  Recruiting Johns Hopkins University · Baltimore, Maryland and 1 other locations · NCT07225205

• Bilateral middle meningeal artery embolization for refractory chronic migraine

  This study will try blocking both middle meningeal arteries with Onyx in adults who have refractory bilateral chronic migraine to see if it is safe and lowers headaches.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07223008

• Pregnenolone to treat cannabis intoxication

  This trial tests whether oral pregnenolone can quickly reverse cannabis intoxication symptoms in healthy adults with prior cannabis use.

  Recruiting Phase 2 Johns Hopkins University · Baltimore, Maryland · NCT07216690

• Effects of Different Cannabis Strains on Perception, Feelings, and Performance

  This study tests how indica, sativa, or generic cannabis affects thinking, mood, and driving-related performance in adults who already use cannabis.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT07214155

• Autobiographically meaningful music with psilocybin to shape set and setting

  This study tests whether personally meaningful music, compared with standard playlists, changes the emotional experience and mood effects of psilocybin in healthy adults aged 21 to 75.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT07180108

• Scrambler therapy for chronic pancreatitis pain

  We will test whether Scrambler Therapy can reduce persistent abdominal pain in adults with chronic pancreatitis who haven't found relief from standard treatments.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07174609

• Long-term outcomes after FETO for severe left or right congenital diaphragmatic hernia

  This trial will test whether performing FETO in fetuses with isolated severe left or right CDH helps more babies survive to hospital discharge and have fewer long-term problems than standard care.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07166172

• Pulmonary rehabilitation to reduce post-tuberculosis lung problems

  This trial tests whether an 8-week or 24-week home-based pulmonary rehabilitation program given during treatment can prevent long-term lung problems in adults with drug-sensitive pulmonary tuberculosis.

  Recruiting at 2 sites Johns Hopkins University · Mangalore and 1 other locations · NCT07164742

• BALANCE: an 8-10 week support program for caregivers with physical or sensory disabilities

  This 8-10 week program tries personalized resource navigation, self-care planning, emergency and end-of-life preparedness, and peer support for adults with physical or sensory disabilities who provide care for someone else, to improve well-being, access to resources, and social connection.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07157995

• Can CBD help with alcohol withdrawal and craving

  This study tests whether cannabidiol (CBD) given with standard care can reduce withdrawal symptoms and craving in adults with moderate-to-severe alcohol use disorder during a short inpatient withdrawal period.

  Recruiting Phase 2/3 Johns Hopkins University · Baltimore, Maryland · NCT07148843

• Short-term effects of oral nicotine pouches

  Researchers will try oral nicotine pouches with adult daily cigarette smokers and adults who rarely use nicotine to see short-term effects on mood, thinking, and nicotine levels.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT07128329

• CAPABLE Care + Connect for older adults experiencing social isolation

  This project will see if combining the CAPABLE home-based support program with Johns Hopkins home-based primary care reduces loneliness and improves daily functioning for older, homebound adults.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07123298

• HomeLink2: structured home care with optional nutrition to reduce deaths after hospital discharge

  This trial will test whether structured home-based medical care and support—with or without food parcels—helps adults living with HIV recover better and reduce deaths in the six months after leaving the hospital.

  Recruiting Johns Hopkins University · Klerksdorp, North West · NCT07102745

• Imlygic (T-VEC) injections for cutaneous neurofibromas in adults with NF1

  This trial will test whether injecting Imlygic into bothersome cutaneous neurofibromas can shrink them or reduce symptoms in adults with NF1 who want local treatment.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT07102394

• 1927-nm Thulium laser for keratosis pilaris on the upper arms

  We will test if the 1927-nm Thulium laser can reduce bumps, roughness, redness, and pigment from keratosis pilaris on the upper arms in adults aged 18–65.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07078461

• Personalized dietitian coaching with digital farmers market to improve blood pressure

  This trial tests if digital farmacy, tailored dietitian guidance, produce prescriptions, and home blood pressure monitoring can help Black and Hispanic adults with high blood pressure in Maryland.

  Recruiting Johns Hopkins University · Baltimore, Maryland and 2 other locations · NCT07075588

• Cystic Fibrosis Wellness Program for Adults with Fatigue

  This pilot randomized trial will try a combined cognitive behavioral therapy and physical activity coaching program to see if it helps adults with cystic fibrosis who have significant fatigue sleep better, move more, and sit less.

  Recruiting Johns Hopkins University · Denver, Colorado and 2 other locations · NCT07071324

• Pediatric-based contraceptive screening and care coordination for Latina mothers

  This project will test a Spanish-language screening and care-coordination program in pediatric clinics to see if it helps Latina immigrant mothers meet their contraceptive needs.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07064837

• Omalizumab for people with COPD who are allergic to common indoor allergens

  This trial will test whether monthly injections of omalizumab (Xolair) help people aged 40+ with COPD who are allergic to and exposed to common indoor allergens reduce symptoms or exacerbations.

  Recruiting at 10 sites Phase 2 Johns Hopkins University · Birmingham, Alabama and 22 other locations · NCT07059091

• Brief motivational counseling with or without a smartphone mindfulness app for teens who drink alcohol

  This study will test whether adding a smartphone mindfulness program to brief motivational counseling helps 12–17-year-olds who drink alcohol cut down and avoid alcohol-related problems over one year.

  Recruiting at 2 sites Johns Hopkins University · Baltimore, Maryland and 12 other locations · NCT07059078

• Psilocybin to reopen brain plasticity after chronic stroke

  This trial will test whether a supervised dose of psilocybin is safe and can help reopen brain plasticity in adults who had an ischemic or hemorrhagic stroke at least 12 months ago.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT07053917

• Arexvy (RSVPreF3) vaccine for people with weakened immune systems

  This trial will test whether one or two doses of the Arexvy RSV vaccine help people with weakened immune systems make protective immune responses and will track side effects.

  Recruiting Phase 2 Johns Hopkins University · Baltimore, Maryland · NCT07050732

• Beauty-salon based plan to manage blood pressure in Black and Hispanic women

  A pilot program tests if training salon stylists to run BP checks, provide home monitoring, and support from community health workers and pharmacists can help Black and Hispanic women with hypertension lower their blood pressure.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07042386

• Emetine for Dengue: seeing if a pill can help adults with dengue work better

  This study tests three groups—emetine 6 mg, emetine 12 mg, or a placebo—to see if a 7-day oral course can improve outcomes for adults with dengue.

  Recruiting Phase 2/3 Johns Hopkins University · Baltimore, Maryland and 1 other locations · NCT07016321

• Cannabidiol (CBD) for reducing stress and nicotine withdrawal in daily cigarette smokers.

  This trial tests whether a single dose of CBD can reduce stress responses and nicotine withdrawal symptoms in adults who smoke cigarettes daily.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT07001930

• Combined MDMA and psilocybin treatment for Veterans with PTSD

  This trial tests whether giving MDMA followed 30 minutes later by psilocybin can be safely used to reduce symptoms in military veterans with long-standing PTSD.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT06989957

• Improving hypertension care in Ghana and Baltimore

  This program tests whether a package of patient-, provider-, and health-system interventions can improve blood pressure control for adults ages 18–70 with hypertension who receive care at participating clinics and own a smartphone.

  Recruiting at 4 sites Johns Hopkins University · Baltimore, Maryland and 16 other locations · NCT06986590

• Improving sleep before knee replacement to reduce post-surgical pain

  This study will see if adding cognitive behavioral therapy for insomnia plus morning bright light is better than negative ion exposure with either CBT-I or sleep/knee education at reducing pain after total knee replacement in people 60+ with knee osteoarthritis who have trouble sleeping.

  Recruiting Johns Hopkins University · Baltimore, Maryland and 1 other locations · NCT06976138

• Resilience in people with opioid use disorder

  This project will test whether short lab tasks performed during stress and non‑stress sessions match up with self‑rated resilience in adults with opioid use disorder.

  Recruiting Johns Hopkins University · Baltimore, Maryland and 1 other locations · NCT06954402

• Omalizumab to increase tolerance to common food allergens in people with high total IgE

  This trial will test whether omalizumab injections every two weeks for 24 weeks, with an optional 8-week twice-weekly extension, can help people with food allergies and very high total IgE tolerate allergic foods.

  Recruiting Phase 2 Johns Hopkins University · Baltimore, Maryland · NCT06934200

• Hearing care to reduce neuropsychiatric symptoms in people with Alzheimer's and related dementias

  This trial will try a tailored, community-delivered hearing care program using HEARS devices to see if it improves communication, reduces neuropsychiatric symptoms, and eases caregiver distress in English-speaking older adults with Alzheimer's disease or related dementias who have untreated hearing loss.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06930560

• Heart to Heart: Community Health Worker support to increase cardiac rehabilitation participation

  This project will try a Community Health Worker–led Heart to Heart program to help adults hospitalized for heart problems who are eligible for cardiac rehabilitation decide about and join cardiac rehab.

  Recruiting at 3 sites Johns Hopkins University · Baltimore, Maryland and 2 other locations · NCT06908590

• Using a prosthetic to prevent complications after skull surgery

  This study is testing if a special helmet can help people who had skull surgery avoid complications and recover better.

  Recruiting at 2 sites Johns Hopkins University · Baltimore, Maryland and 1 other locations · NCT06899711

• Improving HIV treatment options for youth

  This study is testing if personalized treatment options and counseling can help young people with HIV better manage their condition and improve their health.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06886971

• Investigating factors influencing childhood obesity

  This study looks at why some kids become overweight by checking their eating habits, genetics, and brain development to find ways to help prevent or treat obesity early on.

  Recruiting Johns Hopkins University · Baltimore, Maryland and 3 other locations · NCT06861868

• Understanding how the uterus absorbs fluid during early pregnancy

  This study is trying to understand how the uterus absorbs fluid during early pregnancy in women, both with and without endometriosis, to learn more about the process.

  Recruiting Johns Hopkins University · Athens, Georgia and 2 other locations · NCT06847685

• Tirzepatide versus lisdexamfetamine and placebo for adults with obesity and binge-eating disorder

  This trial tests whether tirzepatide helps reduce binge-eating episodes and body weight in adults with obesity and moderate-or-greater binge-eating disorder, compared with lisdexamfetamine or placebo, with all participants receiving guided self-help CBT.

  Recruiting Phase 2 Johns Hopkins University · Baltimore, Maryland · NCT06847399

• AI decision support to help emergency doctors detect and manage acute kidney injury

  This project will test whether an AI-based tool helps emergency doctors find and manage acute kidney injury earlier in adults who have blood creatinine measured during their ED visit.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06840210

• Telerehabilitation for chronic low back pain

  This study tests whether video-based physical therapy can help people with chronic low back pain just as well as traditional in-person therapy.

  Recruiting at 3 sites Johns Hopkins University · Baltimore, Maryland and 2 other locations · NCT06821607

• Nasal microbiota transplant to restore infant nasal microbiome after intranasal mupirocin

  This trial will try a parent-to-child nasal microbiota transplant to see if it restores nasal microbial diversity in newborns after intranasal mupirocin treatment for S. aureus.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT06805994

• Exploring the effects of psychoactive substances similar to classic psychedelics

  This study is testing whether new psychoactive substances can create experiences like classic psychedelics in healthy volunteers.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT06772753

• Epigenetic markers linked to PMDD across the menstrual cycle

  This study tests whether blood epigenetic markers can tell apart women with PMDD from women without PMDD at different points in the menstrual cycle.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06771583

• Integrated STI testing to improve HIV prevention with PrEP for women in Rakai, Uganda

  This project will test whether adding diagnostic tests for curable STIs to routine risk screening helps women in Rakai start and stay on PrEP to prevent HIV.

  Recruiting Johns Hopkins University · Kalisizo · NCT06743204

• Using a new device to improve sense of smell in older adults

  This study is testing a new device to see if it can help older adults improve their sense of smell and overall well-being.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06733636

• Treatment for shoulder pain after stroke

  This study is testing whether hyaluronidase injections can help reduce shoulder pain in stroke survivors and improve their movement and quality of life.

  Recruiting Phase 2 Johns Hopkins University · Baltimore, Maryland · NCT06718413

• Investigating hormone effects on premenstrual dysphoric disorder

  This study is trying to see how certain hormones and a low-dose antidepressant can affect women with premenstrual dysphoric disorder compared to those without it.

  Recruiting at 2 sites Phase 4 Johns Hopkins University · Baltimore, Maryland and 1 other locations · NCT06704594

• Psilocybin therapy for patients with ALS and depression

  This study is testing if psilocybin therapy can help people with ALS who are also feeling depressed.

  Recruiting Early Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT06656702

• Impact of THC on E-Cigarette Use Behavior

  This study is testing how different doses of THC affect daily e-cigarette users' cravings and use behavior.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT06609109

• Impact of THC on Cigarette Smoking Behavior

  This study is testing how different amounts of THC affect smoking habits and cravings in healthy adults who smoke cigarettes and use cannabis.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT06609083

• Using vortioxetine to improve mood and cognition in patients with frontotemporal dementia

  This study is testing if a medication called vortioxetine can help improve mood and thinking skills in people with early-stage behavioral variant Frontotemporal Dementia.

  Recruiting Phase 2 Johns Hopkins University · Baltimore, Maryland · NCT06604520

• Examining the effect of silicone mouth tape on snoring and mild sleep apnea

  This study tests if using silicone mouth tape at night can help adults with snoring and mild sleep apnea breathe better and sleep more soundly.

  Recruiting Phase 2 Johns Hopkins University · Baltimore, Maryland · NCT06587256

• Short-course bedaquiline to prevent TB in people with HIV and recent close contacts

  This tests whether a 4-week course of bedaquiline can prevent active TB in people living with HIV and in close contacts of adults with drug-susceptible or rifampin-resistant TB.

  Recruiting at 6 sites Phase 2/3 Johns Hopkins University · Ulaanbaatar and 7 other locations · NCT06568484

• Preventing violence against women and girls in Somalia

  This study is testing a program in Somalia that aims to change harmful attitudes about gender-based violence and improve support for women and girls by working with both adults and teens in communities and schools.

  Recruiting Johns Hopkins University · Mogadishu, Wadajir District · NCT06554418

• Using methadone during laparoscopic hysterectomy to reduce opioid prescriptions

  This study is trying to see if giving methadone during laparoscopic hysterectomy can help manage pain better and reduce the need for regular opioid painkillers after surgery.

  Recruiting at 2 sites Phase 2 Johns Hopkins University · Baltimore, Maryland and 1 other locations · NCT06536517

• Comparing blue light and white light methods for bladder cancer surgery

  This study is testing whether using blue light during bladder cancer surgery can help patients with high-risk non-muscle invasive bladder cancer have better outcomes than using regular white light.

  Recruiting at 2 sites Phase 3 Johns Hopkins University · Washington D.C., District of Columbia and 1 other locations · NCT06525571

• Health-E You: A mobile app to help adolescent boys talk about sexual health

  A web-based app used before clinic visits helps adolescent males discuss sexually transmitted infections, contraception, and other sexual health topics with their clinician to see if it improves safer behaviors and knowledge.

  Recruiting at 8 sites Johns Hopkins University · Oakland, California and 7 other locations · NCT06525064

• Assessing how meal timing affects glucose tolerance in young people

  This study is testing if eating meals at the right times for their body clocks can help young people aged 17-23 manage their blood sugar better.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06507722

• Mobile health toolkit for managing atrial fibrillation

  This trial will test whether a mobile digital toolkit (Corrie) helps adults with paroxysmal or persistent atrial fibrillation improve quality of life and reduce AFib episodes.

  Recruiting at 2 sites Johns Hopkins University · Baltimore, Maryland and 1 other locations · NCT06500988

• Long-term outcomes after vestibular implantation

  This study is testing how well a balance implant works for adults with chronic balance problems to see if it improves their stability and quality of life over the long term.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06500975

• Dolutegravir plus lamivudine two-drug HIV treatment for people starting rifampin-based TB therapy

  This will test whether a two-drug HIV regimen (dolutegravir plus lamivudine), given either twice daily or as Dovato in the morning plus extra dolutegravir in the evening, works and is safe for ART‑naïve people with HIV who are receiving rifampin-based tuberculosis treatment compared with standard three‑drug therapy.

  Recruiting at 5 sites Phase 3 Johns Hopkins University · Manaus, Amazonas and 4 other locations · NCT06497465

• Improving health for patients with chronic low back pain in rural areas using telerehabilitation

  This study is testing if telerehabilitation can help people with chronic low back pain in rural areas get better access to physical therapy and improve their pain and disability.

  Recruiting at 2 sites Johns Hopkins University · Baltimore, Maryland and 1 other locations · NCT06471920

• Nutrition and community food support for postpartum recovery after gestational diabetes

  This project will test whether a culturally tailored medically provided meal program that lets new mothers switch from prepared to fresh meals helps Black women with obesity who had gestational diabetes manage their weight and diet after childbirth.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06445530

• Evaluating pain management after laparoscopic tubal sterilization

  This study is testing whether a combination of non-opioid pain medications can manage pain just as well as opioids after a laparoscopic tubal sterilization procedure.

  Recruiting Phase 4 Johns Hopkins University · Baltimore, Maryland · NCT06434233

• Mindfulness intervention for managing tics in Tourette syndrome

  This study is testing a mindfulness program to see if it can help adults with Tourette syndrome manage their tics better than traditional therapy.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06408662

• Universal Test and Connect for HIV services in Cape Town emergency departments

  This project tests whether offering universal HIV testing and connection-to-care in two Cape Town emergency departments can find people with HIV or at high risk and link them to treatment or PrEP.

  Recruiting Johns Hopkins University · Cape Town, Western Cape · NCT06408142

• Understanding recovery expectations in acute respiratory failure survivors and their caregivers

  This study looks at how adults who survive acute respiratory failure and their caregivers feel about recovery in the first six months after leaving the hospital to see if shared expectations can help improve their mental health.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06401239

• Effect of Manual Therapy on Voice and Swallowing After Thyroid Surgery

  This study is testing if a special voice therapy program with neck massage and exercises can help people who have voice and swallowing problems after thyroid surgery feel better.

  Recruiting at 2 sites Johns Hopkins University · Baltimore, Maryland and 1 other locations · NCT06383091

• Investigating the effects of THC and d-limonene in healthy adults

  This study is testing if a compound called d-limonene can change how THC affects healthy adults when both are taken together in a pill form.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT06378957

• Improving heart health for low-income individuals with diabetes and obesity

  This study is testing whether a 6-month program that includes training, exercise help, and community support can improve heart health for low-income people with diabetes and obesity compared to regular education and exercise access.

  Recruiting Johns Hopkins University · Baltimore, Maryland and 1 other locations · NCT06364644

• Effects of psilocybin on chronic low back pain and depression

  This study is testing if a single high dose of psilocybin can help people with chronic low back pain and depression feel better.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT06355414

• Improving mental health for survivors of acute respiratory failure

  This study is testing a new self-management program based on therapy to see if it can help reduce anxiety in patients recovering from acute respiratory failure in the ICU.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06341972

• Improving quality of life for kidney transplant waitlist candidates

  This study is testing a new support program to help low-income people on the kidney transplant waitlist who are frail or at risk of frailty improve their physical function and overall well-being.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06326905

• Using CT to Measure Heart Fibrosis in Atrial Fibrillation Patients Before Ablation

  This study tests if measuring heart tissue changes with a CT scan can help predict how well people with Atrial Fibrillation will do after a heart procedure.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06308094

• Assessing heart function in patients with right heart failure

  This study is trying to find better ways to spot and treat right heart problems in people with heart failure and high blood pressure in the lungs by looking at how their heart functions during exercise.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06299436

• Accelerated flap coverage for severe lower leg injuries

  This study is testing if getting surgery to cover severe leg injuries within 72 hours helps reduce infections better than the usual timing for treatment.

  Recruiting at 11 sites Johns Hopkins University · Sacramento, California and 10 other locations · NCT06293469

• Effects of vaporized cannabis and alcohol on impairment

  This study is testing how using alcohol and vaporized cannabis together affects people's ability to think and act, to help understand the risks of mixing these substances.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT06293040

• Text messaging program to engage first-time fathers during pregnancy

  This study tests a text messaging program designed to help first-time dads stay involved during pregnancy and after the baby is born by sending them helpful information and resources.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06289101

• Using metformin to improve asthma control in overweight and obese adults

  This study is testing if the diabetes drug metformin can help overweight or obese adults with asthma feel better and manage their symptoms more effectively.

  Recruiting at 2 sites Phase 2 Johns Hopkins University · Baltimore, Maryland and 1 other locations · NCT06273072

• Kidney transplantation using organs from HIV-positive donors

  This study is testing how well kidney transplants from HIV-positive and HIV-negative donors work for people with HIV and if the donor's HIV status affects the success of the transplant.

  Recruiting at 17 sites Johns Hopkins University · Birmingham, Alabama and 17 other locations · NCT06263426

• Shortened treatment for tuberculosis in children

  This study is testing if a shorter 2-month treatment for tuberculosis works just as well and is safe for children under 10 as the usual 4- to 6-month treatment.

  Recruiting at 9 sites Phase 3 Johns Hopkins University · Chennai and 8 other locations · NCT06253715

• Yoga for back pain in adolescents with scoliosis

  This study tests whether adding a structured yoga program to regular care can help teenagers with scoliosis and back pain feel better and improve their quality of life.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06242821

• Improving parenting skills and school outcomes for PreK children

  This study is testing a parenting program to see if it can help parents improve their skills and get their 4-year-old kids ready for kindergarten in public prekindergarten programs.

  Recruiting Johns Hopkins University · Baltimore, Maryland and 1 other locations · NCT06197997

• Understanding lung health in young adults

  This study is trying to learn more about lung health in healthy young adults aged 25 to 35 by testing how well their lungs work and what might affect their risk of lung disease.

  Recruiting at 12 sites Johns Hopkins University · Birmingham, Alabama and 11 other locations · NCT06177717

• Using Solriamfetol to treat fatigue in Multiple Sclerosis

  This study is testing if a new medication called Solriamfetol can help reduce fatigue in people with Multiple Sclerosis.

  Recruiting Phase 2 Johns Hopkins University · Baltimore, Maryland · NCT06170970

• Comparing Ultra High-Resolution CT to Conventional CT for Heart Disease

  This study is testing whether a new type of heart scan called Ultra High-Resolution CT can find heart disease better than the regular CT scan in people who are at lower risk.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06170541

• Mirdametinib treatment for adults with Neurofibromatosis 1 and skin tumors

  This study is testing a new treatment called mirdametinib to see if it can help adults with Neurofibromatosis 1 and skin tumors feel better and manage their condition.

  Recruiting Phase 1/2 Johns Hopkins University · Baltimore, Maryland · NCT06159166

• Preventing suicidal behavior in high-risk youth in emergency care settings

  This study is testing two different short interventions to see which one better helps young people aged 12-19 who are at risk of suicide when they come to the emergency room.

  Recruiting at 6 sites Johns Hopkins University · St. Petersburg, Florida and 5 other locations · NCT06151158

• A new model to support preschool children's mental health through parenting programs

  This study is testing a new parenting program to see if it can help improve the mental health of preschool children from low-income families who are having behavior issues.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06145477

• Registry for patients with pediatric atopic dermatitis receiving systemic treatments

  This study is creating a registry for kids with severe eczema who are using or planning to use systemic treatments to help researchers learn more about how well these treatments work and keep everyone updated on new options.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06136767

• Investigating the role of senescent cells in uterine fibroids

  This study is trying to see how certain aging cells affect the growth of uterine fibroids to help find better treatments for women dealing with these tumors.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06135870

• Boosting COVID-19 vaccination in Latino communities through social networks

  This study is testing a new way to boost COVID-19 vaccinations in Latino communities by training people to encourage their friends to get vaccinated.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06128928

• Treatment for early-stage osteonecrosis using bone marrow aspirate

  This study is testing whether a treatment using bone marrow from patients can help people with early-stage osteonecrosis of the hip feel better and avoid needing joint replacement.

  Recruiting at 10 sites Johns Hopkins University · Los Angeles, California and 9 other locations · NCT06123481

• Exploring how cerebellar stimulation affects cognitive sequencing

  This study is testing if stimulating a part of the brain called the cerebellum can help people improve their ability to complete tasks that require following a sequence.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06108336

• Syringe-service telemedicine plus social-network HIV prevention program

  This program will test whether training people who inject drugs to recruit and educate their peers through syringe service telemedicine and social networks increases HIV testing and use of prevention and treatment services in Maryland.

  Recruiting Johns Hopkins University · Baltimore, Maryland and 1 other locations · NCT06103370

• Decision-making support for families considering home ventilation for children

  This study is testing a new website to help families and doctors make better decisions about home ventilation for children with chronic breathing issues.

  Recruiting at 4 sites Johns Hopkins University · Tampa, Florida and 3 other locations · NCT06102330

• Observing the effects of kratom products on regular users

  This study looks at how regular users of kratom feel and function after taking their usual dose, while also checking what happens when they stop using it.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06089980

• Oral antibiotic therapy for Gram-negative bloodstream infections

  This study is testing if switching to oral antibiotics early can help adults with Gram-negative bloodstream infections just as well and safely as sticking with IV antibiotics.

  Recruiting at 11 sites Johns Hopkins University · San Francisco, California and 10 other locations · NCT06080698

• Using psilocybin to enhance buprenorphine treatment for opioid use disorder

  This study is testing if a single high dose of psilocybin can help people in outpatient buprenorphine treatment for opioid use disorder feel better and stick to their treatment plan.

  Recruiting Phase 2 Johns Hopkins University · Baltimore, Maryland · NCT06067737

• Evaluating withdrawal symptoms in e-cigarette users

  This study is testing how withdrawal symptoms affect people who only use e-cigarettes when they stop using them for a week, while trying different types of nicotine patches to see how they help.

  Recruiting Early Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT06066996

• Reducing vertigo during MRI scans

  This study is testing if changing how quickly patients enter and exit a strong MRI machine can help reduce dizziness and vertigo during the scan.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06062368

• Peer support and ART provision for HIV-positive individuals transitioning from prison to community

  This study is testing two new ways to help people with HIV who are leaving prison get better care and support in the community to see if they can achieve better health outcomes.

  Recruiting Johns Hopkins University · Johannesburg, Gauteng · NCT06027671

• Comparing PET/CT and Cardiac CT for Detecting Heart Disease

  This study is testing if a new type of imaging called NaF-PET/CT can find heart disease better than the standard cardiac CT in patients showing symptoms of coronary artery disease.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT05994014

• Emotional therapy for people with ongoing pain after orthopedic injuries

  This study is testing if Emotional Awareness and Expression Therapy can help people with ongoing pain after orthopedic injuries feel better both physically and emotionally.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT05989230

• High-relaxivity Elucirem contrast for cardiac MRI to detect myocardial scar

  This test will see if a half dose of Elucirem (gadopiclenol) can detect heart muscle scar as well as a double dose of Dotarem in adults who previously had cardiac MRI.

  Recruiting Phase 4 Johns Hopkins University · Baltimore, Maryland and 1 other locations · NCT05954559

• Wearable Insoles to Help Prevent Diabetic Foot Ulcers

  This study tests Orpyx sensory insoles added to standard care to see if they reduce diabetic foot ulcers in high-risk adults with neuropathy.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT05950659

• mHealth intervention for improving sleep and cognition in low-income older adults

  This study is testing a mobile health program to see if it can help low-income older adults sleep better and think more clearly by encouraging physical activity and providing coaching.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT05935241

• Self-administered gaming and exercise program for stroke recovery

  This study tests whether adding a fun gaming and exercise program to regular therapy can help stroke survivors improve their hand strength and function.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT05929027

• Telemedicine therapy for improving language skills in stroke patients with aphasia

  This study is testing two different online language therapies for stroke patients with aphasia to see which one helps improve their speaking and naming skills better.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT05845047

• Surgeon-driven bone health referral for patients having lower limb joint replacement

  This study is testing if sending patients with osteoporosis to a bone health specialist before getting lower limb joint replacement surgery can help reduce fractures and complications compared to regular care.

  Recruiting Johns Hopkins University · Columbia, Maryland · NCT05845021

• Evaluating anticoagulation strategies for atrial fibrillation using a smart watch

  This study is testing if using a smart watch to monitor heart rhythm can help people with atrial fibrillation take blood thinners only when needed, instead of continuously, to see if it works better for their health.

  Recruiting at 84 sites Phase 3 Johns Hopkins University · Phoenix, Arizona and 92 other locations · NCT05836987

• Monitoring leg pressure in patients on ECMO to prevent compartment syndrome

  This study is testing a new device that continuously checks leg pressure in patients on ECMO to see if it helps prevent serious leg problems better than regular methods.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT05830721

• Asthma management program for children in Baltimore schools

  This study is testing a new asthma management program in Baltimore schools to see if it helps children with asthma miss fewer days of school and feel better overall.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT05814510

• Understanding how stress affects cognitive decline in people at risk for Alzheimer's disease

  This study is testing how stress affects thinking skills in people with mild cognitive impairment who are at risk for Alzheimer's disease to see if certain genes and stress responses can help predict their decline.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT05795634

Showing recruiting studies first, then the newest. Describe your situation to find the ones that fit you.

NIH-funded research (newest 40 of 2997)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Targeting hidden brain injuries in iTTP to improve long-term brain health

  A researcher aims to find out how silent brain injuries in people with immune thrombotic thrombocytopenic purpura (iTTP) happen, how they affect thinking and stroke risk, and how to prevent them.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11638596

• Accelerated flap coverage for severe leg injuries: earlier reconstruction vs standard timing

  This study tests whether doing early flap coverage after a severe leg injury lowers infection risk and improves healing for patients with open wounds and bone injury.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11636988

• Placebo-controlled shunting for iNPH: does the surgery help with walking and balance?

  A doctor-led trial at Johns Hopkins will test whether a shunt surgery improves walking and balance in older adults with idiopathic normal pressure hydrocephalus.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11628947

• Omalizumab for COPD patients with allergen sensitization and exposure

  A multicenter trial will test whether adding omalizumab helps people with COPD who are allergic to common indoor allergens and are exposed to them.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11624859

• Johns Hopkins Total Worker Health Center focusing on mental health

  A nationwide center at Johns Hopkins is working to improve mental health and well-being among workers by studying workplace health strategies and translating findings into practical tools.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11623433

• Role of fat droplets in liver fat and inflammatory signals in NAFLD

  A study at Johns Hopkins will explore how fat droplets in the liver influence molecules that drive inflammation and progression of non-alcoholic fatty liver disease (NAFLD) in adults.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11623263

• Pathogen reduction to prevent infections from blood transfusions

  A Johns Hopkins-led project will study how often infections pass from donated blood to patients and whether a pathogen-reduction technology can prevent these transmissions.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11623202

• Pathogen reduction to prevent infections from blood transfusions

  A Johns Hopkins-led study will explore how to reduce the risk of infections from donated blood by using advanced pathogen-reduction technology and detailed testing to keep patients safer.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11623201

• Adjuvant Steroid Therapy for idiopathic subglottic stenosis in a multicenter randomized trial

  A multicenter randomized trial will test whether injecting steroids into the narrow airway repeatedly can help people with idiopathic subglottic stenosis breathe better and reduce procedures.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11621813

• How the cerebellum controls our movements

  A doctor-scientist team at Johns Hopkins is studying how the cerebellum uses error signals to fine-tune movements in primates, with the goal of improving movement disorders in people.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11618984

• Hopkins Population Center supports people-focused health research

  A Johns Hopkins center provides resources and collaboration to study how demography and population health affect families, children, and reproductive health.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11616935

• Structured Peer-led ART and Reentry Support to Stay in HIV Care After Prison in South Africa

  A program using peer facilitators to help people reentering society after prison in South Africa stay on HIV treatment and keep accessing care.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11611055

• Understanding how post-TB lung disease develops after TB in rural Uganda

  This grant aims to study how lung problems after TB arise and who is most at risk, using data from a large cohort in rural Uganda.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11609909

• How mitochondrial, lysosome, and immune problems affect dry age-related macular degeneration

  This grant looks at how stress in eye cells’ powerhouses, waste disposal systems, and immune signals may contribute to early dry AMD in people who carry specific genetic risk.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11609399

• Hopkins Hub: Accelerating HIV Implementation Science to End the Epidemic

  A regional hub from Johns Hopkins aims to strengthen HIV implementation research and collaborations to help end the HIV epidemic.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11609182

• Multi-level stigma reduction for women living with HIV in Malawi

  A practical program tests a stigma‑reduction package to help women with HIV in Malawi stick to ART and achieve viral suppression.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11608604

• Pulmonary rehabilitation to reduce breathing problems after tuberculosis

  A program of guided exercise and breathing training to help adults who have recovered from TB breathe better and feel healthier.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11607184

• Pulmonary rehab to reduce breathing troubles after TB

  A program of pulmonary rehabilitation is being studied to help adults who have completed TB treatment avoid ongoing lung problems and improve daily breathing.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11607183

• HIV research collaboration in Uganda to prevent mother-to-child transmission and improve adult HIV treatment

  This grant supports Johns Hopkins to run Uganda clinical trial sites that test new HIV prevention and treatment approaches, helping diverse adults and mothers-to-be in Uganda access cutting-edge care.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11607147

• mHealth tool to boost physical therapy outcomes for adults with musculoskeletal pain

  A mobile health app is being tested to help adults in physical therapy stay on track with home exercises and improve pain and function.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11607117

• Long-term heart and metabolic health in women with HIV on a DTG-based ART

  This study follows women with HIV over five years to compare how a dolutegravir-based therapy versus an alternative regimen affects heart and metabolic health across the lifespan.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11605887

• Cardiometabolic Health in Women with HIV on DTG-Based ART Across Life Stages

  A long-term study following women with HIV to see how dolutegravir-based therapy affects heart and metabolic health compared with another ART regimen.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11605886

• Shigella infection in children: Does antibiotics help non-dysenteric watery diarrhea in kids 0-11?

  In kids aged 0-11 with non-dysenteric watery diarrhea caused by Shigella, this study tests whether giving antibiotics improves recovery and growth.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11604328

• Shigella illness in kids: treatment and rapid diagnosis in young children

  This study tests whether giving antibiotics to children with non-dysenteric Shigella diarrhea improves health and growth, using rapid tests to guide treatment in Bangladesh and Zambia.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11604327

• Rakai Community Cohort Study: A Resource for Infectious Disease Research

  A long-running health data and biospecimen resource from Uganda is being preserved and expanded to help study HIV, other infections, and related health questions.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11604071

• HIV Prevention and Treatment Trials in Uganda through Johns Hopkins Clinical Trial Unit

  This grant supports Johns Hopkins' Uganda Clinical Trial Unit to run HIV prevention and treatment studies across Uganda, aiming to help end the global HIV pandemic.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11603151

• HIV Prevention and Treatment Research in Uganda through Johns Hopkins- Uganda Clinical Trial Unit

  A Johns Hopkins research group in Uganda is renewing support to run HIV prevention and treatment trials to help end the global HIV/AIDS epidemic.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11603150

• Johns Hopkins Malawi HIV Clinical Trials Unit

  This grant supports a Malawi-based HIV research center run by Johns Hopkins to help people affected by HIV/AIDS through international collaborations and clinical trials.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11601635

• NeuroTech Harbor - Transition: Finishing and Handing Off Neurotechnology Projects

  A Johns Hopkins-led program to wrap up and smoothly hand off neurotechnology projects funded by NIH, ensuring all results, plans, and documentation are ready for the next phase or closure.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11601072

• Direct from patient samples: whole genome sequencing of Neisseria gonorrhoeae to map STI spread in African communities with high HIV burden

  A small study will test a faster way to read the genetic makeup of Neisseria gonorrhoeae directly from patient samples to better understand how sexually transmitted infections spread in communities with high HIV rates.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11600906

• New Horizons in preventing and treating food allergy

  A Johns Hopkins-led effort aims to advance how we prevent and treat food allergies across all ages by coordinating high-quality studies and developing better therapies.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11600582

• Virology Core supporting hepatitis B and HIV cure research

  A Virology Core at Johns Hopkins helps test patient samples with standardized HBV assays and develops new tests to support multiple projects aimed at finding a functional cure for hepatitis B in people living with HIV and others.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11600461

• Global HBV and HIV Cure Cohort and Data/Specimen Resource Platform

  A global effort to create a large cohort of people living with HIV and hepatitis B to study cure approaches and build a shared data and specimen resource for researchers.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11600460

• HBV cure insights in people living with HIV or HBV

  A Johns Hopkins team is studying how hepatitis B virus behaves in the blood of people with HIV or HBV to move toward a functional cure.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11600459

• Virology Core for HBV/HIV Cure Research

  A Johns Hopkins team runs standardized HBV tests and develops new assays to support multiple projects in the HBV/HIV cure effort, using participant samples collected across several sites.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11600328

• Global HBV/HIV cure research network and data repository

  A Johns Hopkins-led project will create a global group and shared data/biobank to accelerate research toward curing hepatitis B and HIV co-infection.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11600327

• HBV cure clues in people with and without HIV

  This project studies how HBV-specific B and T cell responses relate to curing hepatitis B in people with and without HIV.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11600326

• HBV cure research in people living with HIV or HBV

  Researchers at Johns Hopkins are studying how hepatitis B virus persists in people with HIV or HBV to help move toward a functional cure.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11600325

• Virology Core: key lab services for hepatitis B and HIV cure research

  A Johns Hopkins-led Virology Core will run advanced HBV testing and support across multiple international projects to help move toward a functional cure for HBV in people living with HIV.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11600324

• HBV cure study in people living with HIV or HBV

  Researchers at Johns Hopkins are studying hepatitis B in people with HIV to understand how the virus behaves in blood and how the body responds, with the goal of moving toward a functional cure.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11600304

Quick answers

How many clinical trials run by Johns Hopkins University are recruiting right now?

241, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 22 countries. The most sites are in United States (227 trials), South Africa (6 trials), Canada (3 trials), Uganda (3 trials), India (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 27, Phase 1: 23, Phase 4: 10, Phase 3: 9. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →