CAPABLE Care + Connect for older adults experiencing social isolation
Official title: CAPABLE Care + Connect: Pilot Feasibility of Implementing CAPABLE Into Homebased Primary Care
Run by Johns Hopkins University · NCT07123298 · Data updated 2026-11-12
This project will see if combining the CAPABLE home-based support program with Johns Hopkins home-based primary care reduces loneliness and improves daily functioning for older, homebound adults.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 50 Years and up |
| Sex | All |
| Enrollment | 450 (estimated) |
| Sponsor | Johns Hopkins University Academic / other |
| Locations | 1 site (Baltimore, Maryland) |
| Status | Recruiting |
| Started | August 14, 2025 |
| Main results expected | May 2027 |
| Study ends | May 2027 |
| Registry record updated | June 2, 2026 |
| Trial ID | NCT07123298 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are JHOME enrollees aged 50 or older who live in Baltimore City or County, have some difficulty with ADLs, screen positive for isolation or loneliness, are cognitively intact (MOCA > 23), and are not receiving active cancer treatment.
✕Probably not a fit
Patients who are terminally ill, live in long-term care settings, have significant cognitive impairment, have frequent recent hospitalizations, or live outside Baltimore City/County are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This mixed-methods pilot adapts the evidence-based CAPABLE home-based program to patients enrolled in Johns Hopkins Home-Based Medicine (JHOME) to address social isolation and disability. Participants receive an individually tailored 4-month intervention delivered by an occupational therapist, a registered nurse, and a handy worker with a series of home visits and supportive services. Eligibility focuses on JHOME patients aged 50 or older who report social isolation or loneliness and are cognitively intact; outcomes include function in ADLs/IADLs and measures of social connection. The study integrates quantitative measures and qualitative feedback to test feasibility and potential impacts before scaling.
Why it matters
Potential benefit: If successful, this combined approach could reduce loneliness and improve independence in daily activities, raising quality of life for homebound older adults.
How similar studies have gone: CAPABLE itself has shown improvements in ADLs, IADLs, and depression, but combining CAPABLE with home-based primary care specifically to address social isolation is a novel application with limited prior evidence.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Any patient currently in JHOME * At risk for or experiencing social isolation as defined by the Lubben Social Network Scale 6 item score less than or equal 12 points or loneliness as defined by the UCLA Loneliness Scale 3 item score of 6 to 9 points * Cognitive inclusion criteria Montreal Cognitive Assessment (MOCA) \>23 as determined by referring JHOME study team member provider * English speaking (measures are standardized in English) * Ability to participate in an approximately 45-60 min virtual or in person meeting * Eligible for CAPABLE * 50 years or older * Not hospitalized over night more than 4 times in the last 12 months * Have some difficulty with any ADL * Cognitively intact * Live in Baltimore County or Baltimore City * Not receiving active cancer treatment * Interested in participating in CAPABLE Care partners will be included if the care partners provide \> 10 hours of care/week Exclusion Criteria: * Terminally ill * live in long term care setting * receiving active cancer treatment Standard of Care/Comparison group Inclusion Criteria: • Any patient currently in JHOME who did not receive the CAPABLE intervention
Where it's running
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Johns Hopkins School of Nursing
Baltimore, Maryland, United States Recruiting
Study contacts
- Principal investigator: Thomas Cudjoe, MD, MPH, MA — Johns Hopkins University
- Study coordinator: Chloe Wynn, MS
- Email: cwynn3@jh.edu
- Phone: 667-208-7444
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.