Personalized dietitian coaching with digital farmers market to improve blood pressure

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

iTHRIVE is a two-arm randomized trial enrolling 21-70 year-olds who are Black/African American or Hispanic/Latino with hypertension and related CKM conditions. Participants receive digital access to produce prescriptions and culturally tailored dietitian coaching plus home blood pressure monitoring, with an active comparator to standard care. The study focuses on residents in high food priority areas to address disparities in CKM-related health. Outcomes will relate to blood pressure, diet, and metabolic markers, with emphasis on access and adherence to nutritious food choices. The trial is led by Johns Hopkins University with collaborations from the AHA and NIMHD and takes place at affiliated Maryland sites.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 21-70 years
* Self-identify as Black/African American or Hispanic/Latino
* Have Stage 2 CKM defined as:
* Systolic BP ≥130mmHg (measured at screening) AND at least one of:
* Hypertension (ICD-10: I10-I16)
* Prediabetes (HbA1c 5.7-6.4%) or Type 2 Diabetes (HbA1c ≥6.5%)
* Stage 3 chronic kidney disease (CKD) (eGFR 30-59 mL/min/1.73m²)
* Live in census tracts identified by the Montgomery/ Prince George's/Baltimore City County Departments of Planning as HFPA:
* Healthy Food Availability Index score is low (0-9.5),
* Median household income ≤185% of Federal Poverty Level

  * 30% of households have no vehicle,
* Distance to supermarket \>1/4 mile. 5. Have refrigeration, food preparation appliances (microwave, stove), and cell phones for the App

Exclusion Criteria:

* Age \<21 years
* Diagnosis of end-stage renal disease (ESRD), dialysis
* Serious medical condition that either limits life expectancy or requires active management (e.g., cancer)
* Significant food allergies, preferences, intolerances, or dietary requirements that would interfere with diet adherence
* Active alcohol or substance use disorder (i.e., not sober/abstinent for ≥ 30 days)
* Patients with cognitive impairment or other condition preventing their participation in the intervention
* Pregnant, breastfeeding, or planning pregnancy
* Current participation in a care management program related to health conditions (e.g., weight reduction, smoking cessation) or another clinical trial that could interfere with the study protocol
* Planning to move out of the geographic area in 12 months

Where it's running

• Johns Hopkins Community Physicians
  Baltimore, Maryland, United States Recruiting
• Johns Hopkins School of Nursing
  Baltimore, Maryland, United States Not yet recruiting
• Holy Cross Hospital
  Gaithersburg, Maryland, United States Not yet recruiting

Study contacts

• Principal investigator: Oluwabunmi Ogungbe, PhD, MPH, RN — Johns Hopkins School of Nursing
• Study coordinator: Oluwabunmi Ogungbe, PhD, MPH, RN
• Email: oogungb3@jh.edu
• Phone: 410-614-1519

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Using low-dose aspirin after preeclampsia to improve recovery

  This study is testing if taking low-dose aspirin for six months after having preeclampsia can help new moms recover better by improving their blood pressure and blood vessel function.

  Recruiting Phase 4 University of Pittsburgh · Pittsburgh, Pennsylvania · NCT06281665

• IMB-guided health education to boost medication taking and blood pressure control in adults with hypertension

  This study tests a health-literacy program based on Information-Motivation-Behavioral Skills to help adults with hypertension who don’t take their medicines regularly to take them more consistently and better control their blood pressure.

  Recruiting at 8 sites Bahir Dar University · Ādēt and 7 other locations · NCT07894068

• Renal Nerve Stimulation to Help Blood Pressure in AF and HFpEF

  This study tests whether stimulating the kidneys with a catheter can safely lower blood pressure in adults with atrial fibrillation and HFpEF who also have hypertension.

  Recruiting London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · London, Ontario · NCT07893821

• Hypertension: Does Education Help Patients Manage Blood Pressure Better?

  This study tests whether structured patient education improves blood pressure control and self-management in adults with hypertension who speak Turkish.

  Recruiting Inonu University · Batman, Center · NCT07890090

• High BMI and periodontitis in Thai adults under 60

  This study tests how common high BMI and periodontitis are among Thai adults aged 18–59 and what factors are linked to them.

  Recruiting Mahidol University · Bangkok, Ratchathewi · NCT07880717

• Long-term GW906 treatment for people with essential hypertension

  This trial tests whether long-term GW906 injections are safe and effective for adults with essential hypertension who completed an earlier GW906 study.

  Recruiting Shenzhen Salubris Pharmaceuticals Co., Ltd. · Shanghai, Shanghai Municipality · NCT07879755

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.