Understanding recovery expectations in acute respiratory failure survivors and their caregivers

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates how adults who survive acute respiratory failure (ARF) and their caregivers perceive the recovery process during the first six months post-discharge. Participants will complete three surveys that assess their expectations, feelings, and mental health symptoms. The study aims to explore the relationship between shared expectations within survivor-care partner dyads and their coping strategies. By analyzing these dynamics, the research seeks to identify factors that may improve mental health outcomes for both survivors and their caregivers.

Why it matters

Who can join: the full rules

Patient Inclusion Criteria:

* ≥18 years old
* Meets study definition of ARF:

  * The study defines ARF as meeting 1 of the following 3:

    1. Mechanical ventilation via an endotracheal tube ≥24 consecutive hours OR
    2. Non-invasive ventilation (CPAP, BiPAP) ≥24 consecutive hours that is not for obstructive sleep apnea or other stable use OR
    3. High flow nasal cannula with fraction of inspired oxygen (FIO2)≥.5 and flow rate ≥ litres per minute (LPM) for ≥24 consecutive hours.
  * Occasional rest periods of ≤1 hour are not deducted from the calculation of consecutive hours. Patients who are intubated for mental status or airway obstruction are not eligible unless they have simultaneous ARF.
* Survival to hospital discharge to home
* Speaks or reads English or Spanish
* Identifies an adult who is expected to act as a primary care partner for at least the next 6 months.

Patient Exclusion Criteria:

* Pre-existing cognitive impairment (IQ-CODE \>3.6)
* Residing in a medical institution at hospital discharge
* Receiving hospice care or life expectancy \<6 months
* Homelessness or recent history of psychosis

Care Partner Inclusion Criteria:

* ≥18 years old
* Speaks or reads English or Spanish

Care Partner Exclusion Criteria:

* Pre-existing cognitive impairment (IQ-CODE \>3.6)

Where it's running

• Johns Hopkins Hospital
  Baltimore, Maryland, United States Recruiting

Study contacts

• Principal investigator: Ann M Parker, MD, PhD — Johns Hopkins University
• Study coordinator: Ann M Parker, MD, PhD
• Email: ann.parker@jhmi.edu
• Phone: 410-955-2190

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.