Virology Core supporting hepatitis B and HIV cure research
Official title: Virology Core
Funded at Johns Hopkins University · NIH-11600461 · Data updated 2026-11-12
A Virology Core at Johns Hopkins helps test patient samples with standardized HBV assays and develops new tests to support multiple projects aimed at finding a functional cure for hepatitis B in people living with HIV and others.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | September 17, 2025 |
| Project end | July 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $88,487 |
| NIH project number | 3U19AI188551-02S3 |
| Project ID | NIH-11600461 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with chronic hepatitis B, including people with HIV co-infection, and control groups with hepatitis B only, across participating sites.
✕Less likely to help
Individuals not living with hepatitis B or HIV may not directly benefit from this core's activities.
What this research studies
This core provides high-quality virology testing on participant samples collected across global sites, focusing on hepatitis B surface antigen dynamics in people living with HIV and hepatitis B. It standardizes and optimizes assays to enable reliable data for all related projects and supports the use of lab models to advance experiments. By coordinating with the Shared Resources Core, the Virology Core helps ensure that results are timely, accurate, and usable for statistical analyses. The work aims to move toward a functional HBV cure by characterizing viral markers during treatment in diverse participant groups and controls.
Why it matters
Potential benefit: Patients could benefit from improved testing methods and rigorous data to guide strategies toward functional cure for hepatitis B in the context of HIV co-infection.
How similar studies have gone: Previous efforts have shown that standardized HBV testing and detailed virological characterization can inform cure-directed strategies, though this exact multi-site core approach is ongoing.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Thio, Chloe L — Johns Hopkins University
- Study coordinator: Thio, Chloe L
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.