Improving hypertension care in Ghana and Baltimore

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The ADHINCRA Program implements a bundle of multilevel, evidence-based interventions that address patient-, provider-, and health-system factors contributing to uncontrolled hypertension. The program is being delivered at primary care sites in the Ashanti Region of Ghana and at Johns Hopkins in Baltimore, with smartphone-supported components and clinic-based workflow changes. Eligible participants are adults 18–70 with systolic BP ≥140 mmHg who are treatment-naive or on monotherapy, while people with severe hypertension, diabetes, established cardiovascular or kidney disease, pregnancy, or cognitive impairment are excluded. The aim is to increase hypertension control rates and produce a rigorous, scalable model for wider adoption to reduce future cardiovascular, stroke, and kidney disease risk.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Aged 18 -70 years.
* Diagnosis of hypertension and elevated systolic blood pressure measure (≥140 mmHg) on the most recent clinic visit without a diabetes diagnosis.
* Hypertension treatment naive or on monotherapy.
* Receives primary care at one of the participating sites.
* Willing and able to provide informed consent in English, Twi, Dagbani, Ewe, Hausa, or Yoruba.
* Owns a smartphone (Android or iOS).

Exclusion Criteria:

* Age \<18 years or \>70 years.
* Severely elevated BP (≥180/110mmHg).
* Diagnosis of stroke, coronary artery disease, or kidney disease.
* Diagnosis of end-stage renal disease (ESRD) treated with dialysis.
* Serious medical condition which either limits life expectancy or requires active management (e.g., cancer).
* Cognitive impairment or other conditions preventing study participation
* Pregnant or currently nursing a child
* Unwilling to provide informed consent

Where it's running

• Manhyia Government Hospital
  Kumasi, Ashanti Region, Ghana Recruiting
• St. John of God Catholic Hospital
  Duayaw Nkwanta, Bono, Ghana Recruiting
• Northern Regional Hospital
  Tamale, Northern Region, Ghana Recruiting
• Akure South Hospital
  Akure, Ondo State, Nigeria Recruiting
• Johns Hopkins University
  Baltimore, Maryland, United States Active not recruiting
• Dominase SDA Hospital
  Bekwai, Ashanti Region, Ghana Not yet recruiting

Study contacts

• Principal investigator: Yvonne Commodore-Mensah, PhD, MHS, RN — Johns Hopkins University
• Study coordinator: Yvonne Commodore-Mensah, PhD, MHS, RN
• Email: ycommod1@jhmi.edu
• Phone: 410-614-1519

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.