Improving quality of life for kidney transplant waitlist candidates
Official title: Addressing Inactive Kidney Transplant Waitlist Status Through Adapting a Tailored Psycho-Social-Environmental Program
Run by Johns Hopkins University · NCT06326905 · Data updated 2026-11-12
This study is testing a new support program to help low-income people on the kidney transplant waitlist who are frail or at risk of frailty improve their physical function and overall well-being.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 99 Years |
| Sex | All |
| Enrollment | 43 (estimated) |
| Sponsor | Johns Hopkins University Academic / other |
| Locations | 1 site (Baltimore, Maryland) |
| Status | Recruiting |
| Started | January 25, 2025 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | July 20, 2026 |
| Trial ID | NCT06326905 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and older who are on the deceased donor kidney transplant waitlist and are either inactive or low-income active candidates.
✕Probably not a fit
Patients who are on the living donor waitlist, have severe cognitive impairment, or are expected to be inactive for more than three months may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study adapts the CAPABLE program to create CAPABLE Transplant, aimed at helping individuals on the kidney transplant waitlist who are frail or at risk of frailty. It involves a mixed methods approach with an open label pilot followed by a randomized control trial to assess the feasibility and acceptability of the intervention. Participants will receive tailored support from an occupational therapist, registered nurse, and handy worker over four months to enhance their physical function and overall well-being. The study focuses on low-income individuals who are either inactive or have been inactive on the waitlist due to various health and social factors.
Why it matters
Potential benefit: If successful, this intervention could significantly improve the quality of life and functional status of patients awaiting kidney transplants.
How similar studies have gone: Previous studies using the CAPABLE program have shown success in improving outcomes for functionally vulnerable older adults, suggesting potential for this adapted approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Deceased Donor Waitlist * ≥18 years old * Community dwelling * Current Inactive status or active and had been inactive in the last 18 months for cardiovascular disease, frailty, obesity, social support, mental health, incomplete testing OR Active on the waitlist and low-income Exclusion Criteria: * Living Donor Waitlist * Severe cognitive impairment * Inactivity expected to last \> 3 months (eg cancer treatment) * \>4 hospitalizations in the last 12 months * Current home nursing, physical or occupational therapy
Where it's running
-
Johns Hopkins School of Nursing
Baltimore, Maryland, United States Recruiting
Study contacts
- Principal investigator: Melissa Hladek, PhD — Johns Hopkins School of Nursing
- Study coordinator: Melissa Hladek, PhD
- Email: mhladek1@jh.edu
- Phone: 4106142418
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.