Clinical trial Recruiting at 8 sites Interventional Ages 18 and up

Augmented reality CPR feedback for pediatric resuscitation

Official title: AR-CPR: Large-Scale Simulation-Based Testing of a Novel Augmented Reality Point of Care Chest Compression Feedback System

Run by Johns Hopkins University · NCT07778823 · Data updated 2026-11-12

This study tests whether AR-CPR feedback can help healthcare teams deliver high-quality chest compressions in simulated pediatric cardiac arrest, as compared with coaching from a CPR expert.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment252 (estimated)
SponsorJohns Hopkins University
Academic / other
Locations8 sites (St. Petersburg, Florida and 7 other locations)
StatusRecruiting
StartedJune 29, 2025
Main results expectedMarch 31, 2028
Study endsJune 30, 2028
Registry record updatedAugust 26, 2026
Trial IDNCT07778823 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Active pediatric ED or ICU nurses or clinical technicians with current PALS certification and experience as CPR coaches at participating sites.

Probably not a fit

Participants who have difficulty performing chest compressions or lack corrective lenses without availability may not benefit from the AR-CPR feedback.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a multicenter, randomized, international simulation study comparing an augmented reality CPR feedback system to human coaching during an 18-minute simulated pediatric cardiac arrest. Teams of nurses and clinical technicians with PALS certification perform chest compressions on a high-fidelity pediatric manikin, with one arm using AR-CPR and the other receiving real-time guidance from a CPR coach. The trial is non-inferiority and focuses on whether AR-CPR achieves guideline-recommended rate and depth of compressions as well as recoil. It is unblinded and conducted across eight institutions in the US and Canada, with the primary outcome being the percentage of compressions meeting target metrics. Participants are pediatric ED/ICU staff, organized into teams of 1–3 members, and the intervention isolates chest compression performance to evaluate feedback modality effects.

Why it matters

Potential benefit: If successful, AR-CPR could provide real-time, scalable feedback to improve CPR quality during pediatric resuscitations.

How similar studies have gone: Prior approaches using real-time feedback for CPR have shown mixed but promising improvements in performance; this study tests a novel AR modality against human coaching.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Actively credentialed pediatric emergency department or pediatric intensive care unit nurse or clinical technician at a participating study site
* Current American Heart Association (AHA) Pediatric Advanced Life Support (PALS) certification

Exclusion Criteria:

* Inability to physically perform chest compressions
* Need for prescription corrective lenses without having those corrective lenses available at the time of study participation

Where it's running

  • All Childrens Hopsital
    St. Petersburg, Florida, United States
    Recruiting
  • Johns Hopkins Children's Center
    Baltimore, Maryland, United States
    Recruiting
  • Columbia University Vagelos College of Physicians and Surgeons
    New York, New York, United States
    Recruiting
  • Childrens Hospital of Philadelphia
    Philadelphia, Pennsylvania, United States
    Recruiting
  • Brown/Hasbro Children's Hospital
    Providence, Rhode Island, United States
    Recruiting
  • University of Texas Southwestern Medical center/ Children's Health of Dallas
    Dallas, Texas, United States
    Recruiting
Show 2 more locations
  • Texas Childrens
    Houston, Texas, United States
    Recruiting
  • The hospital for sick children
    Toronto, Ontario, Canada
    Recruiting

Study contacts

  • Principal investigator: Jutin Jeffers, MD — Johns Hopkins University
  • Study coordinator: Keith Kleinman, MD
  • Email: kkleinm3@jh.edu
  • Phone: 410-955-5000

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.