Clinical trial Recruiting at 1 site Interventional Ages 50 and up

Strength and Pain-Coping Through Resilience and Knowledge for Older Adults

Official title: Strength and Pain-Coping Through Resilience and Knowledge

Run by Johns Hopkins University · NCT07228520 · Data updated 2026-11-12

The SPARK program tests a home-based, nurse-delivered intervention to help adults 50 and older with pain, depressive symptoms, and mobility limits see if their pain and mood improve.

Quick facts

Study typeInterventional
Ages50 Years and up
SexAll
Enrollment100 (estimated)
SponsorJohns Hopkins University
Academic / other
Locations1 site (Baltimore, Maryland)
StatusRecruiting
StartedJune 1, 2026
Main results expectedNovember 30, 2028
Study endsNovember 30, 2028
Registry record updatedJuly 22, 2026
Trial IDNCT07228520 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Community-dwelling adults aged 50 and older in Central Maryland who have persistent pain, depressive symptoms, and mobility limitations, and are pre-frail or frail.

Probably not a fit

Individuals without significant pain interference or depressive symptoms, or those not meeting frailty criteria, may receive little or no benefit from the intervention.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

SPARK is a home-based behavioral program delivered by nurses to community-dwelling older adults with mobility challenges. It consists of eight weekly 1:1 nurse visits focusing on goal-directed care, pain and mood self-management, and coordination with local resources. The goal is to reduce pain interference with daily activities and lower depressive symptoms, improving overall function and well-being. The study uses the Neighborhood Nursing model to bring care directly to participants’ homes in Central Maryland. Eligibility targets adults 50+ with significant pain, depressive symptoms, a pre-frail or frail status, and at least one ADL/IADL limitation.

Why it matters

Potential benefit: If successful, participants may experience less pain interference and improved mood, potentially enhancing daily functioning and independence.

How similar studies have gone: Prior studies in similar home-based, nurse-delivered behavioral programs have shown improvements in pain interference and mood in older adults; this study builds on that approach for a targeted, regional population.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Self-report pain \>3 out of a 0 -10 scale that has lasted longer than 3 months and keeps subjects from doing at least one activity that subjects would like to do
* Live in the community
* Live in Central Maryland
* Score a 5 or higher on the PHQ-9 (depression measure) at least two times during a two week period (screening call and then at first data collection visit)
* Must be pre-frail (one or two criteria on frailty phenotype) or frail (three or more of the criteria on frailty phenotype)
* One ADL or IADL limitation

Exclusion Criteria:

* Hospitalized \> 3 times in the last year
* Participating in physical therapy
* Have a terminal diagnosis (\<1 year expected survival)
* \> moderate intellectual impairment (5-7 errors) based on the Short Portable Mental Status Questionnaire (SPMSQ)
* Unable to speak or understand English

Where it's running

  • Johns Hopkins School of Nursing
    Baltimore, Maryland, United States
    Recruiting

Study contacts

  • Principal investigator: Janiece L Taylor, PhD — Johns Hopkins School of Nursing
  • Study coordinator: Janiece Taylor, PhD
  • Email: jwalke90@jhu.edu
  • Phone: 443-287-4503

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.