Pulmonary rehabilitation to reduce breathing problems after tuberculosis
Official title: TB PuRe : Pulmonary rehabilitation to reduce post-tuberculosis morbidity
Funded at Johns Hopkins University · NIH-11607184 · Data updated 2026-11-12
A program of guided exercise and breathing training to help adults who have recovered from TB breathe better and feel healthier.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $36,629 |
| NIH project number | 3R01AI169588-04S1 |
| Project ID | NIH-11607184 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with a history of TB who have residual lung impairment and can participate in a rehabilitation program.
✕Less likely to help
Patients without mobility or health conditions that prevent rehabilitation participation may see little or no benefit.
What this research studies
If you’ve had tuberculosis and still have trouble breathing, this project tests whether a structured pulmonary rehabilitation program can lessen lingering lung problems and improve daily living. It will be implemented in India and studied for its effectiveness, practicality, and cost. The team will look at how well people can participate, what benefits they notice, and whether the program could be financially sustainable. The study is led by Johns Hopkins and collaborators to see if this approach can be scaled beyond the clinic.
Why it matters
Potential benefit: If successful, patients could experience easier breathing, more activity tolerance, and better quality of life after TB.
How similar studies have gone: Pulmonary rehabilitation has shown benefits for chronic lung diseases, but its use specifically during TB treatment to prevent post-TB morbidity is being tested in this project.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Golub, Jonathan E. — Johns Hopkins University
- Study coordinator: Golub, Jonathan E.
Related research
Other NIH-funded projects on the same topics.
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Pulmonary rehab to reduce breathing troubles after TB
A program of pulmonary rehabilitation is being studied to help adults who have completed TB treatment avoid ongoing lung problems and improve daily breathing.
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Pulmonary rehabilitation to reduce breathing problems after TB
A program of supervised breathing and exercise therapy is tested to see if it helps people who have recovered from tuberculosis breathe better and feel better.
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Pulmonary rehabilitation to prevent post-TB lung problems
This project offers and compares two home-based breathing and exercise programs for adults with TB to help prevent long-term lung problems after treatment.
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Pulmonary rehabilitation to prevent lung problems after tuberculosis
Two home-based breathing and exercise programs are offered to adults being treated for tuberculosis to help protect lung health after treatment.
-
Pulmonary rehabilitation to prevent lung problems after tuberculosis
This project compares two home-based breathing and exercise programs given during TB treatment to help adults prevent long-term lung problems after pulmonary tuberculosis.
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Improving lung health for people recovering from tuberculosis
This study is looking at two different home exercise programs to help people who have finished tuberculosis treatment breathe better and feel healthier, while also making sure these programs are easy to use and affordable for everyone.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.