Global HBV and HIV Cure Cohort and Data/Specimen Resource Platform
Official title: Shared Resources Core
Funded at Johns Hopkins University · NIH-11600460 · Data updated 2026-11-12
A global effort to create a large cohort of people living with HIV and hepatitis B to study cure approaches and build a shared data and specimen resource for researchers.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | September 17, 2025 |
| Project end | July 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $88,487 |
| NIH project number | 3U19AI188551-02S3 |
| Project ID | NIH-11600460 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals living with HIV and chronic hepatitis B, including diverse geographic backgrounds, who could contribute data, samples, or participate in future studies.
✕Less likely to help
Participants not directly enrolled in a clinical trial may not receive a direct therapeutic benefit.
What this research studies
This grant sets up a worldwide group of participants with HIV and HBV to study how a cure might work in diverse settings. It will create a centralized data and specimen repository in Baltimore and a platform to share information so researchers can collaborate effectively. Johns Hopkins leads the effort, connecting US and non-US sites with industry and academic partners to accelerate HBV cure research.
Why it matters
Potential benefit: If successful, it could speed the development of cures for people living with HIV and HBV and improve access to research-ready samples and data.
How similar studies have gone: Previous HBV/HIV cohorts and data-sharing platforms have advanced understanding, but a truly global, harmonized resource remains an unmet need.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Thio, Chloe L — Johns Hopkins University
- Study coordinator: Thio, Chloe L
Related research
Other NIH-funded projects on the same topics.
-
Targeting hidden brain injuries in iTTP to improve long-term brain health
A researcher aims to find out how silent brain injuries in people with immune thrombotic thrombocytopenic purpura (iTTP) happen, how they affect thinking and stroke risk, and how to prevent them.
-
Accelerated flap coverage for severe leg injuries: earlier reconstruction vs standard timing
This study tests whether doing early flap coverage after a severe leg injury lowers infection risk and improves healing for patients with open wounds and bone injury.
-
Placebo-controlled shunting for iNPH: does the surgery help with walking and balance?
A doctor-led trial at Johns Hopkins will test whether a shunt surgery improves walking and balance in older adults with idiopathic normal pressure hydrocephalus.
-
Omalizumab for COPD patients with allergen sensitization and exposure
A multicenter trial will test whether adding omalizumab helps people with COPD who are allergic to common indoor allergens and are exposed to them.
-
Johns Hopkins Total Worker Health Center focusing on mental health
A nationwide center at Johns Hopkins is working to improve mental health and well-being among workers by studying workplace health strategies and translating findings into practical tools.
-
Role of fat droplets in liver fat and inflammatory signals in NAFLD
A study at Johns Hopkins will explore how fat droplets in the liver influence molecules that drive inflammation and progression of non-alcoholic fatty liver disease (NAFLD) in adults.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.