Pulmonary rehab to reduce breathing troubles after TB
Official title: TB PuRe : Pulmonary rehabilitation to reduce post-tuberculosis morbidity
Funded at Johns Hopkins University · NIH-11607183 · Data updated 2026-11-12
A program of pulmonary rehabilitation is being studied to help adults who have completed TB treatment avoid ongoing lung problems and improve daily breathing.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $81,234 |
| NIH project number | 3R01AI169588-04S2 |
| Project ID | NIH-11607183 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults (21+ years) with a history of TB and persistent lung impairment who can participate in a pulmonary rehabilitation program.
✕Less likely to help
If a patient has contraindications to exercise or cannot access rehabilitation services, benefits may be limited.
What this research studies
This project tests a structured pulmonary rehabilitation program in India to see if it can reduce post-TB lung symptoms, improve function, and be cost-effective. Researchers will measure how well the program works in real-world care settings and whether it can be feasibly implemented within existing health systems. The study also considers the program’s practicality for US TB survivors, given rising TB cases and shared lung-impairment concerns. The work is designed to inform new care options for people who have survived TB but continue to struggle with breathing and quality of life.
Why it matters
Potential benefit: If successful, patients could experience better breathing, more daily activity, and a lower burden of lung-related problems after TB.
How similar studies have gone: Previous pulmonary rehabilitation work shows improvements in chronic lung disease, but this specific post-TB reduction approach is novel and its effectiveness is being tested.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Golub, Jonathan E. — Johns Hopkins University
- Study coordinator: Golub, Jonathan E.
Related research
Other NIH-funded projects on the same topics.
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Pulmonary rehabilitation to reduce breathing problems after tuberculosis
A program of guided exercise and breathing training to help adults who have recovered from TB breathe better and feel healthier.
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Pulmonary rehabilitation to reduce breathing problems after TB
A program of supervised breathing and exercise therapy is tested to see if it helps people who have recovered from tuberculosis breathe better and feel better.
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Pulmonary rehabilitation to prevent post-TB lung problems
This project offers and compares two home-based breathing and exercise programs for adults with TB to help prevent long-term lung problems after treatment.
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Pulmonary rehabilitation to prevent lung problems after tuberculosis
Two home-based breathing and exercise programs are offered to adults being treated for tuberculosis to help protect lung health after treatment.
-
Pulmonary rehabilitation to prevent lung problems after tuberculosis
This project compares two home-based breathing and exercise programs given during TB treatment to help adults prevent long-term lung problems after pulmonary tuberculosis.
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Improving lung health for people recovering from tuberculosis
This study is looking at two different home exercise programs to help people who have finished tuberculosis treatment breathe better and feel healthier, while also making sure these programs are easy to use and affordable for everyone.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.