Surgeon-driven bone health referral for patients having lower limb joint replacement
The Impact of a Surgeon-Initiated Bone Health Referral Pathway on Implant-Related Complications in Patients With Osteoporosis Undergoing Lower Extremity Arthroplasty
This study is testing if sending patients with osteoporosis to a bone health specialist before getting lower limb joint replacement surgery can help reduce fractures and complications compared to regular care.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 2000 (estimated) |
| Ages | 50 Years and up |
| Sex | All |
| Sponsor | Johns Hopkins University Academic / other |
| Locations | 1 site (Columbia, Maryland) |
| Trial ID | NCT05845021 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of a surgeon-initiated bone health referral pathway for patients with osteoporosis undergoing lower extremity arthroplasty. Patients will be randomly assigned to either the treatment group, which receives a referral to endocrinology for specialized care, or the control group, which follows standard care with their primary care provider. The study aims to compare rates of fragility fractures and implant-related complications between the two groups. By analyzing outcomes, the researchers hope to determine if the specialized referral pathway improves patient care and reduces complications.
Who should consider this trial
Good fit: Ideal candidates are individuals over 50 years old with a DEXA-confirmed diagnosis of osteoporosis.
Not a fit: Patients with a prior diagnosis or treatment for osteoporosis may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved bone health management and reduced complications for patients undergoing joint replacement surgery.
How similar studies have performed: Other studies have shown that specialized referral pathways can improve patient outcomes, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * \>50 * DEXA-confirmed diagnosis of osteoporosis Exclusion Criteria: * Prior diagnosis of osteoporosis * Prior treatment for osteoporosis
Where this trial is running
Columbia, Maryland
- Charter Professional Center — Columbia, Maryland, United States (Recruiting)
Study contacts
- Principal investigator: Savyasachi Thakkar, MD — Johns Hopkins School of Medicine
- Study coordinator: Savyasachi C Thakkar, MD
- Email: sthakka2@jhmi.edu
- Phone: 443-997-2663
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.