Self-administered gaming and exercise program for stroke recovery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares the effectiveness of standard care with additional self-administered hand therapy for stroke survivors experiencing hand weakness. Participants will be divided into three groups: two will receive daily exercise routines or use a novel electronic device that combines hand therapy with video game-like tasks, while the control group will receive standard outpatient therapy. The study aims to assess improvements in hand function through standardized metrics after the intervention period. Occupational therapists will supervise the therapy sessions via telemedicine to ensure safety and proper technique.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age 21 years and over
2. Stroke confirmed by CT or MRI within the previous 6 weeks.
3. Arm and/or hand impairment induced by the stroke.
4. Meet JSTTEP criteria and are enrolled in JSTTEP.
5. Admitted to the Johns Hopkins Hospital (JHH) inpatient stroke service.
6. Proficient in speaking and reading English.
7. Willing and capable to contacted remotely for all necessary telemedicine contacts.
8. No history of prior ischemic or hemorrhagic stroke with associated motor deficits (prior stroke with no upper limb motor symptoms is allowed)
9. Ability to give informed consent.

Exclusion Criteria:

1. Arm impairment that is too severe (FM-UE \< 40) on day of baseline testing prior to beginning of the study.
2. Recent Botox injection to upper limb (since stroke onset).
3. History of physical or neurological condition that interferes with study procedures or assessment of motor function (e.g. severe arthritis, severe neuropathy, Parkinson's disease).
4. Terminal illness with life expectancy \< 6 months.
5. Inability to sit in a chair and perform hand exercises for 20 minutes at the time.
6. Cognitive impairment, with score on Montreal Cognitive Assessment (MoCA) ≤ 20.
7. Social and/or personal circumstances that prevent telemedicine follow-up.

Where it's running

• Johns Hopkin
  Baltimore, Maryland, United States Recruiting

Study contacts

• Principal investigator: Steven R Zeiler, M.D, Ph.D. — Johns Hopkins University
• Study coordinator: Steven R. Zeiler, M.D., Ph.D.
• Email: sz@jhmi.edu
• Phone: 3035207404

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Dual-task balance training plus computer-based cognitive training after stroke

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.