Emotional therapy for people with ongoing pain after orthopedic injuries

Emotional Awareness and Expression Therapy for People With Persistent Pain Following Orthopedic Trauma: A Pilot Feasibility Study

Not applicable Interventional Johns Hopkins University · NCT05989230

This study is testing if Emotional Awareness and Expression Therapy can help people with ongoing pain after orthopedic injuries feel better both physically and emotionally.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages18 Years and up
SexAll
SponsorJohns Hopkins University Academic / other
Locations1 site (Baltimore, Maryland)
Trial IDNCT05989230 on ClinicalTrials.gov

What this trial studies

This trial aims to assess the feasibility of Emotional Awareness and Expression Therapy (EAET) for individuals suffering from persistent pain following orthopedic trauma. Participants will attend weekly EAET sessions and undergo various assessments, including questionnaires and sensory testing, before, after, and during follow-up. The study addresses the psychological distress often accompanying orthopedic injuries, such as depression and anxiety, which can exacerbate pain and disability. By targeting emotional regulation related to traumatic events, EAET may provide a novel approach to improving both pain and mood in this population.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older who have sustained acute orthopedic injuries and experience persistent pain.

Not a fit: Patients who do not have orthopedic injuries or those whose pain is not persistent may not benefit from this therapy.

Why it matters

Potential benefit: If successful, this therapy could significantly reduce chronic pain and improve emotional well-being for patients recovering from orthopedic trauma.

How similar studies have performed: While few psychological interventions exist for this population, recent findings suggest that similar approaches like EAET have shown promise in improving pain and mood.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* One or more acute orthopedic injuries
* The patient sustained an orthopedic injury including, but not limited to:

  * Pelvic or acetabulum fracture
  * Open/displaced comminuted fracture of long bones
  * Upper extremity injuries with a major nerve involvement
  * Injuries with significant injuries to major blood vessels
  * Traumatic amputation of big toe, thumb, or proximal to the wrist or ankle.
* Initial admission to the trauma or orthopedic center/service of the participating hospital OR all necessary screening and patient characteristic data available in medical record (determination based on information available at time of enrollment)
* 18 years old or older
* Received operative fixation for at least one acute orthopaedic injury at a participating hospital. Patients should be recruited at the time of primary injury, not revision or complication surgery
* Average Brief Pain Inventory Score \> 3/10
* Presence of pain most days (\> 3 days/week) for past three months

Exclusion Criteria:

* peri-prosthetic fractures of the femur (regardless of etiology)
* non-ambulatory due to an associated spinal cord injury
* non-ambulatory pre-injury
* currently pregnant
* moderate or severe traumatic brain injury (TBI), as evidenced by intracranial hemorrhage present on admission CT
* major amputation(s) of the upper or lower extremities
* non-English speaking
* Likely to have severe problems with maintaining follow-up for any of the following reasons:

  * The patient has been diagnosed with a severe psychiatric conditions
  * The patient has current alcohol and/or drug addiction based on medical record or patient self-report.
  * The patient is intellectually challenged without adequate family support
  * The patient lives outside the hospital's catchment area
  * The patient follow-up is planned at another medical center
  * The patient is a prisoner
  * The patient is homeless
  * Other

Where this trial is running

Baltimore, Maryland

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Orthopaedic TraumaChronic PainMusculoskeletal Injury
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.