Long-term outcomes after vestibular implantation

Long Term Outcomes After Vestibular Implantation

Not applicable Interventional Johns Hopkins University · NCT06500975

This study is testing how well a balance implant works for adults with chronic balance problems to see if it improves their stability and quality of life over the long term.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment32 (estimated)
Ages22 Years to 90 Years
SexAll
SponsorJohns Hopkins University Academic / other
Locations1 site (Baltimore, Maryland)
Trial IDNCT06500975 on ClinicalTrials.gov

What this trial studies

This study evaluates the long-term effects of a vestibular implant designed to restore balance and reduce symptoms of chronic imbalance in individuals with bilateral vestibular hypofunction. It involves a single-arm open-label approach, focusing on adults who have previously received a vestibular implant and have been monitored for at least six months. The study aims to assess safety and effectiveness through various measures, including postural stability and patient-reported quality of life. A total of 15 participants will be included, with a focus on both ototoxic and non-ototoxic cases.

Who should consider this trial

Good fit: Ideal candidates are adults over 22 years old who have previously been implanted with a vestibular implant and enrolled in specific Johns Hopkins University protocols.

Not a fit: Patients who have not undergone vestibular implantation or are younger than 22 years old may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a new treatment option for patients suffering from chronic imbalance and improve their quality of life.

How similar studies have performed: Previous studies have shown promising results with vestibular implants in ototoxic cases, indicating potential for success in this novel application.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria

* Adults older than 22 years old who
* have previously been enrolled in Johns Hopkins University Institutional Review Board protocol NA\_00051349, IRB00335294 or IRB00346924 and
* have previously been implanted with a vestibular implant under FDA IDE G150198

Where this trial is running

Baltimore, Maryland

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Bilateral Vestibular HypofunctionBilateral Vestibular DeficiencyBilateral VestibulopathyGentamicin OtotoxicityAminoglycoside ToxicityVestibular DiseasesSensation DisordersLabyrinth Diseases
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.