Investigating the role of senescent cells in uterine fibroids

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study evaluates how senescent cells contribute to the development of uterine fibroids, which are common tumors in the uterus. Researchers are utilizing advanced computational methods to explore the interactions between senescent and immune cells within fibroid tissues. The goal is to understand the communication networks that lead to fibrosis, potentially paving the way for new treatment options for women suffering from uterine fibroids.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Subjects must be women above the age of ≥18 - ≤55 years.
* Women with suspected uterine fibroids.
* Subject must be or have been sexually active or have had a previous vaginal exam that used a speculum.
* Subject must be able to understand, read and speak English or Spanish and subsequently, be able to understand what she is consenting to in terms of procedures and use/disclosure of protected health information.

Exclusion Criteria:

* Unwilling to sign the consent form or complete questionnaire.
* Pregnancy.
* Cancer of the uterus

Where it's running

• Johns Hopkins Hospital
  Baltimore, Maryland, United States Recruiting

Study contacts

• Principal investigator: James Segars, MD — Johns Hopkins University
• Study coordinator: James Segars, MD
• Email: jsegars2@jhmi.edu
• Phone: 410-614-2000

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.