Risk-informed shared-decision making to help people with prediabetes prevent diabetes
Official title: Pilot Trial of a Risk-informed Shared-decision Engagement Strategy
Run by Johns Hopkins University · NCT07553325 · Data updated 2026-11-12
This study tests whether a risk-informed shared decision-making visit or a plain patient portal message can help adults with prediabetes take steps to prevent diabetes.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 120 (estimated) |
| Sponsor | Johns Hopkins University Academic / other |
| Locations | 1 site (Frederick, Maryland) |
| Status | Recruiting |
| Started | August 7, 2026 |
| Main results expected | September 1, 2027 |
| Study ends | April 1, 2028 |
| Registry record updated | August 28, 2026 |
| Trial ID | NCT07553325 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with prediabetes (HbA1c 5.7–6.4% or fasting glucose 100–125 mg/dL) who have BMI ≥ 25, an active MyChart account, and receive primary care at Johns Hopkins Community Physicians Frederick.
✕Probably not a fit
Individuals with diabetes, dementia, or prior participation in the Diabetes Prevention Program may not benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study will compare two approaches to encourage preventive actions in adults with prediabetes: a risk-informed shared decision-making visit with a healthcare team member and a simple patient portal message about diabetes risk, each versus standard clinic care. Participants will have HbA1c or fasting glucose in the prediabetes range and an active MyChart account, and will complete surveys at baseline and up to two follow-ups. The study uses two interventions—RISE and Low Touch Messaging—to see if risk information prompts more steps toward prevention. The trial is conducted at Johns Hopkins Community Physicians in Frederick, with Johns Hopkins University as the lead sponsor and the American Diabetes Association as a collaborator.
Why it matters
Potential benefit: If successful, participants may be more likely to take preventive actions to lower their diabetes risk.
How similar studies have gone: Prior work in risk communication and decision support has shown potential to influence health behaviors, though the specific RI SE and LTM approaches are being evaluated here.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * prediabetes based on most recent HbA1c (5.7-6.4%) or fasting plasma glucose (100-125 mg/dL) in prior 12 months * active patient portal account (MyChart) * patient receiving primary care at Johns Hopkins Community Physicians in Frederick * have overweight or obesity (BMI ≥ 25 kg/m2) Exclusion Criteria: * have diabetes (HbA1c \> 6.4% in prior 6 months or on diabetes registry) * have dementia * previously participated in the Diabetes Prevention Program (DPP)
Where it's running
-
Johns Hopkins Community Physicians Frederick
Frederick, Maryland, United States Recruiting
Study contacts
- Principal investigator: Eva Tseng, MD, MPH — Johns Hopkins University
- Study coordinator: Research Study Coordinator
- Email: preventdiabetes@jh.edu
- Phone: 410-614-4396
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.