Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Peer support for liver transplant recipients with a history of alcohol use disorder

Official title: Peer Support to Enhance Care for Liver Transplant Recipients Who Had Alcohol-Associated Liver Disease

Run by Johns Hopkins University · NCT07397598 · Data updated 2026-11-12

This study tests whether having a peer support specialist helps liver transplant recipients with prior alcohol use disorder stay abstinent and stay engaged in care.

More Alcohol Use Disorder trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment95 (estimated)
SponsorJohns Hopkins University
Academic / other
Locations1 site (Baltimore, Maryland)
StatusRecruiting
StartedOctober 27, 2026
Main results expectedJune 2029
Study endsJune 2029
Registry record updatedOctober 28, 2026
Trial IDNCT07397598 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

English-speaking adults who had a liver transplant for alcohol-associated liver disease and have 1–3 years of continuous abstinence at trial entry.

Probably not a fit

Individuals without a history of alcohol-associated liver disease or those not abstinent for 1–3 years at entry may see little or no benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-arm study adds peer support specialists to routine post-transplant care for liver transplant recipients with alcohol-related liver disease, starting in years 2–4 after transplant. PSSs provide structured, confidential conversations, active listening, and brief counseling to support adherence to medical care and reduce relapse risk. Outcomes will include self-reported and biomarker-based alcohol use, continuation in follow-up with transplant teams, and overall survival, compared to a historical control group. The trial aims to see if peer support improves long-term recovery and health maintenance after liver transplantation for ALD.

Why it matters

Potential benefit: If successful, patients may maintain abstinence longer and stay engaged with medical care, potentially improving survival.

How similar studies have gone: Past studies in other chronic conditions suggest peer support can improve adherence and outcomes, but this specific approach in ALD/LT patients is novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* English speakers
* Received a liver transplant for alcohol-associated liver disease
* Has 1 to 3 years of continuous alcohol abstinence at the time of trial entry

Exclusion Criteria:

* Liver transplant recipients without a history of alcohol-associated liver disease
* Inability to provide informed consent
* Active participation in a separate intervention trial for alcohol use disorder

Where it's running

  • Johns Hopkins University School of Medicine
    Baltimore, Maryland, United States
    Recruiting

Study contacts

  • Principal investigator: Po-Hung Chen, MD, PhD — Johns Hopkins University
  • Study coordinator: Po-Hung Chen, MD, PhD
  • Email: pchen37@jhmi.edu
  • Phone: 410-550-1793

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.