Condition

Acute Respiratory Distress Syndrome clinical trials and research

• 58Clinical trials
• 45NIH research projects
• 29Countries

Newest Acute Respiratory Distress Syndrome clinical trials

All recruiting trials (58)

• Full-Course ECMO Pathway for Moderate-to-Severe ARDS

  This study tests a standardized, full-course ECMO management pathway to see if it improves care for adults with moderate-to-severe ARDS treated with VV-ECMO in real-world Chinese centers.

  Recruiting at 15 sites Southeast University, China · Beijing and 38 other locations · NCT07726953

• Height measurement methods to guide ventilator settings in ARDS

  We’re testing whether more precise height measurements change how researchers set lung-protective tidal volumes in adults with ARDS who are on a ventilator.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT07595926

• Corticosteroids for a hyperinflammatory state in critical illness

  This trial tests whether methylprednisolone helps improve organ function and survival in adults with sepsis or ARDS who show a hyperinflammatory profile.

  Recruiting Phase 2 Peking Union Medical College Hospital · Beijing, Beijing Municipality · NCT07511582

• Right‑heart function and heart–lung interaction during ARDS with mechanical ventilation

  This project will follow adults with ARDS on mechanical ventilation to see how positive‑pressure breathing affects the right heart over time and how that relates to circulation.

  Recruiting Bicetre Hospital · Le Kremlin-Bicêtre · NCT07450846

• Umbilical‑cord mesenchymal stem cell and secretome therapy for severe ARDS

  This trial tests whether IV umbilical‑cord mesenchymal stem cells, alone or with secretome, help adults with severe ARDS recover lung function and reduce inflammation.

  Recruiting Phase 1/2 PT. Prodia Stem Cell Indonesia · Jakarta Pusat, DKI Jakarta · NCT07439848

• Human umbilical cord mesenchymal stem cell injection for moderate to severe ARDS

  This will test whether a single injection of human umbilical cord mesenchymal stem cells can help adults with moderate to severe ARDS that hasn't improved after standard treatment.

  Recruiting Phase 1/2 Changchun Tuohua Pharmaceutical Co., Ltd. · Wuhan, Hubei · NCT07413978

• PrismaLung+ carbon dioxide removal for ventilated ICU patients

  This study will test whether adding PrismaLung+, a device that removes CO2 from the blood, helps adults on invasive mechanical ventilation who have high carbon dioxide levels.

  Recruiting at 9 sites Vantive Health LLC · Beijing, Beijing Municipality and 9 other locations · NCT07326215

• Using inflammatory subtypes to personalize treatment for adults with ARDS

  This project will test whether dividing adults with ARDS on ventilators into 'hyperinflammatory' and 'hypoinflammatory' groups works in Chinese hospitals and can help guide care.

  Recruiting Southeast University, China · Nanjing, Jiangsu · NCT07289711

• Prone positioning for adults with moderate-to-severe ARDS in the ICU

  This study will see how prone positioning ventilation works for adults with moderate-to-severe ARDS and whether it is safe for people who also have acute brain injury.

  Recruiting Southeast University, China · Nanjing, Jiangsu · NCT07284888

• Extended prone positioning for adults with severe ARDS on mechanical ventilation

  This trial tests whether keeping intubated adults with severe ARDS prone for about 40 hours per session lowers deaths compared with the standard ~16-hour sessions.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT07126964

• ARISE: Upright bed positioning for acute respiratory distress syndrome

  This pilot trial will test whether daily upright bed positioning helps adults hospitalized with acute respiratory distress syndrome compared with standard head-of-bed elevation.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT07025421

• Using lung ultrasound to diagnose ARDS in patients on mechanical ventilation

  This study is testing if lung ultrasound can help doctors quickly diagnose ARDS in patients on mechanical ventilation, comparing it to CT scans.

  Recruiting Tanta University · Tanta · NCT06971042

• Effect of expiratory time constant (RCexp) on lung ventilation and blood flow in ventilated ARDS patients

  This tests whether the expiratory time constant (RCexp) changes how air and blood are distributed in the lungs of adults with ARDS who are on mechanical ventilation.

  Recruiting Southeast University, China · Nanjing, Jiangsu · NCT06919484

• Comparing prolonged and daily prone positioning for ARDS patients

  This study is testing if keeping patients with severe lung problems face down for longer periods helps them survive and have fewer complications compared to the usual shorter face-down sessions.

  Recruiting at 38 sites Pontificia Universidad Catolica de Chile · Buenos Aires and 37 other locations · NCT06854627

• Determining the best duration for patients with ARDS in the prone position

  This study is testing how long patients with Acute Respiratory Distress Syndrome should stay in a face-down position to see if it helps their breathing and reduces inflammation.

  Recruiting National Taiwan University Hospital · Taipei · NCT06827184

• Using near apneic ventilation with ECMO for severe respiratory distress

  This study is testing if a new way of breathing support called near apneic ventilation can help patients with severe respiratory distress on ECMO recover better and faster than the usual care.

  Recruiting at 11 sites Phase 3 Assistance Publique - Hôpitaux de Paris · Bobigny and 10 other locations · NCT06814340

• Innovative therapies for Acute Respiratory Distress Syndrome

  This study is testing new treatments for adults in the hospital with Acute Respiratory Distress Syndrome to see if they can improve breathing and overall recovery compared to a placebo.

  Recruiting at 27 sites Phase 2 PPD Development, LP · Birmingham, Alabama and 40 other locations · NCT06703073

• Evaluating vilobelimab for treating Acute Respiratory Distress Syndrome

  This study is testing if vilobelimab can help hospitalized adults with Acute Respiratory Distress Syndrome feel better and improve their chances of recovery compared to a placebo.

  Recruiting at 28 sites Phase 2 PPD Development, LP · Birmingham, Alabama and 40 other locations · NCT06701682

• Evaluating a new treatment for Acute Respiratory Distress Syndrome

  This study is testing a new treatment called paridiprubart to see if it can help hospitalized adults with Acute Respiratory Distress Syndrome breathe better and improve their chances of recovery.

  Recruiting at 28 sites Phase 2 PPD Development, LP · Birmingham, Alabama and 40 other locations · NCT06701669

• Evaluating Bevacizumab for Acute Respiratory Distress Syndrome

  This study is testing whether a medication called bevacizumab can help hospitalized adults with Acute Respiratory Distress Syndrome breathe better and improve their chances of recovery.

  Recruiting at 28 sites Phase 2 PPD Development, LP · Birmingham, Alabama and 40 other locations · NCT06701656

• Investigating Dead Space and Inhaled Nitric Oxide in Children with Acute Respiratory Distress Syndrome

  This study is testing if a specific marker can help predict the risk of death in children with acute respiratory distress syndrome and see how well inhaled nitric oxide treatment works for them.

  Recruiting Children's Hospital Los Angeles · Los Angeles, California and 9 other locations · NCT06690801

• Observing physiological changes in ARDS patients in the prone position

  This study looks at how lying on the stomach affects breathing and oxygen levels in patients with Acute Respiratory Distress Syndrome to see if it can help improve their recovery.

  Recruiting West China Hospital · Chengdu, Sichuan · NCT06586736

• Assessing lung overdistension in ARDS patients using Electrical Impedance Tomography

  This study is testing how to find the best breathing support settings for patients with severe lung issues by using special technology to see how well their lungs are working while they are on a ventilator.

  Recruiting at 2 sites University Hospital, Bordeaux · Bayonne and 1 other locations · NCT06536543

• IC14 (anti-CD14) treatment for hospitalized patients with ARDS

  This will test whether IC14, an antibody that blocks CD14, can improve oxygenation in adults hospitalized with ARDS who are on mechanical ventilation.

  Recruiting at 2 sites Phase 2 Implicit Bioscience · Seattle, Washington and 1 other locations · NCT06513949

• Comparing closed-loop synchronization to conventional synchronization in noninvasive ventilation for breathing patients

  This study is testing if a new automatic breathing device helps adults using noninvasive ventilation breathe better compared to standard methods.

  Recruiting Başakşehir Çam & Sakura City Hospital · Izmir · NCT06357780

• Investigating the role of specific neutrophils in influenza outcomes

  This study is trying to see if certain types of white blood cells in people with severe influenza can help explain why some patients survive while others do not.

  Recruiting University Hospital, Bordeaux · Bordeaux and 1 other locations · NCT06254313

• Prenatal prevention and treatment strategy for neonatal ARDS

  We will test whether giving antenatal corticosteroids to pregnant women who are predicted to be at high risk of neonatal ARDS can reduce newborn lung fluid problems, ARDS severity, and death.

  Recruiting The Second Affiliated Hospital of Chongqing Medical University · Chongqing · NCT06188195

• Understanding reverse trigger in patients on mechanical ventilation

  This study looks at how often patients with severe lung problems on mechanical ventilation experience a condition called reverse trigger, to see how it affects their treatment and recovery.

  Recruiting Hospital Civil de Guadalajara · Guadalajara · NCT06148467

• Comparing precision ventilation to standard care for ARDS

  This study tests if a personalized breathing method can help people with Acute Respiratory Distress Syndrome survive better than the usual care they receive.

  Recruiting at 30 sites Phase 3 Beth Israel Deaconess Medical Center · Tucson, Arizona and 32 other locations · NCT06066502

• Evaluating the impact of transpulmonary mechanical power on patients with severe ARDS on ECMO

  This study is trying to see if measuring the power of breathing machines can help doctors predict how well patients with severe lung problems on ECMO will do and improve their treatment.

  Recruiting Beijing Chao Yang Hospital · Beijing, Beijing Municipality · NCT06062212

• Using nalbuphine for pain management in ARDS patients after surgery

  This study is testing if nalbuphine can help manage pain and anxiety better than another pain medication for patients with Acute Respiratory Distress Syndrome after surgery.

  Recruiting Phase 4 Qianfoshan Hospital · Jinan, Shandong · NCT06037330

• Investigating sedation methods for patients with Acute Respiratory Distress Syndrome on ventilators

  This study is testing whether using different sedation methods helps patients with Acute Respiratory Distress Syndrome on ventilators breathe better and feel more comfortable in the ICU.

  Recruiting Phase 2/3 Guy's and St Thomas' NHS Foundation Trust · London, London · NCT06014138

• Exploring biomarkers and lung damage in ARDS patients

  This study is trying to see if certain signs in the lungs and blood can help identify ARDS patients, especially those with COVID-19, who are at risk of lung damage from treatment, so that doctors can better manage their care.

  Recruiting Università Vita-Salute San Raffaele · Cagliari and 3 other locations · NCT06001645

• Treatment for Acute Respiratory Distress Syndrome with rhu-pGSN

  This study is testing a new treatment called rhu-pGSN to see if it can help people with moderate-to-severe Acute Respiratory Distress Syndrome caused by pneumonia or infections feel better when combined with standard care.

  Recruiting at 63 sites Phase 2 BioAegis Therapeutics Inc. · Los Angeles, California and 64 other locations · NCT05947955

• Erythropoietin's effect on lung fluid clearance in ARDS patients

  This study is testing if giving erythropoietin (EPO) can help patients with acute respiratory distress syndrome (ARDS) clear fluid from their lungs faster and improve their chances of surviving in the hospital.

  Recruiting Second Affiliated Hospital of Wenzhou Medical University · Wenzhou, Zhejiang · NCT05857891

• Examining the link between blood markers and pulmonary embolism in ARDS patients

  This study is testing if certain blood markers can help understand the risk of pulmonary embolism in patients with Acute Respiratory Distress Syndrome (ARDS) in the ICU.

  Recruiting Assistance Publique Hopitaux De Marseille · Marseille · NCT05855317

• Improving care for patients with acute respiratory distress syndrome in the ICU

  This study looks at how following specific care guidelines and providing better nutrition can help improve the health and quality of life for patients with acute respiratory distress syndrome in the ICU.

  Recruiting Japanese Society for Early Mobilization · Tokyo · NCT05844579

• Using imaging to assess risk of lung injury in ARDS patients

  This study is testing if using advanced imaging can help doctors spot lung problems early in patients with acute respiratory distress syndrome (ARDS) to better manage their care.

  Recruiting at 2 sites Università Vita-Salute San Raffaele · Catanzaro, Calabria and 1 other locations · NCT05816954

• Vascular ARDS Recruitment After Inhaled Nitric Oxide

  This study tests whether inhaled nitric oxide can improve blood flow in the lungs of adults with ARDS and ventilation-perfusion mismatch who are on mechanical ventilation.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT05801224

• Understanding how white blood cells affect lung inflammation in patients on ventilators

  This study is trying to see how a type of white blood cell affects lung inflammation in adults on ventilators, especially those with Acute Respiratory Distress Syndrome, to help improve treatments for lung injuries.

  Recruiting National Jewish Health · Denver, Colorado · NCT05767671

• Comparing weaning strategies during ECMO therapy for ARDS

  This study is testing two different ways to help patients with severe lung problems on ECMO therapy breathe better by seeing if it's better to wean them off the ventilator first or the ECMO machine first.

  Recruiting University Hospital Tuebingen · Tübingen, Baden-Wurttemberg · NCT05640635

• Link between lung pressure and fluid in patients with ARDS

  This study looks at how lung pressure and fluid levels are connected in patients with acute respiratory distress syndrome (ARDS) who are on a ventilator.

  Recruiting Bicetre Hospital · Le Kremlin-Bicêtre · NCT05474196

• Personalized tidal volume adjustment for patients with ARDS

  This study is testing if adjusting breathing settings on ventilators based on individual patient needs can help people with Acute Respiratory Distress Syndrome breathe better and improve their chances of recovery.

  Recruiting Hospices Civils de Lyon · Lyon · NCT05406570

• Treatment for Acute Respiratory Distress Syndrome using Extracellular Vesicles

  This study is testing a new treatment called ExoFlo to see if it can help hospitalized patients with moderate-to-severe Acute Respiratory Distress Syndrome breathe better and improve their overall health.

  Recruiting at 31 sites Phase 3 Direct Biologics, LLC · Phoenix, Arizona and 31 other locations · NCT05354141

• Avalanche-like opening of airways during ventilation in ARDS

  This project will test whether airways in adults with moderate-to-severe ARDS open in an 'avalanche' pattern during mechanical ventilation.

  Recruiting Poitiers University Hospital · Poitiers · NCT05224323

• Identifying subtypes of acute hypoxemic respiratory failure in emergency patients

  This study is trying to identify different types of acute respiratory failure in emergency patients to see how these types affect their chances of recovery and treatment options.

  Recruiting Evangelismos Hospital · Athens, Attica · NCT05150483

• Registry for monitoring CytoSorb device use in critically ill patients

  This study is collecting information on how the CytoSorb device helps critically ill patients to improve care for conditions like septic shock and acute respiratory distress syndrome.

  Recruiting at 24 sites CytoSorbents, Inc · Klagenfurt and 27 other locations · NCT05146336

• Ultra-protective lung ventilation with extracorporeal CO2 removal for ARDS

  This study is testing a new way of helping people with moderate Acute Respiratory Distress Syndrome (ARDS) breathe better while protecting their lungs from damage caused by ventilators.

  Recruiting University of Bologna · Bologna · NCT04903262

• Using surfactant in preterm newborns with NRDS or NARDS

  This research will try to see if giving one dose versus two or more doses of surfactant helps preterm infants with NRDS or NARDS.

  Recruiting Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · Chongqing, Chongqing Municipality · NCT04777760

• Optimizing blood flow in patients on veno-venous ECMO

  This study is testing if adjusting blood flow during ECMO treatment can help patients with severe breathing problems get better oxygen without needing as much blood flow.

  Recruiting Charite University, Berlin, Germany · Berlin · NCT04754854

• Evaluating the impact of high PEEP on breathing effort in ARDS patients

  This study is testing if using high levels of breathing support can make it easier for patients recovering from Acute Respiratory Distress Syndrome to breathe on their own.

  Recruiting Sanatorio Anchorena San Martin · San Martín, Buenos Aires · NCT04524091

• Assessing the safety and feasibility of upright positioning for patients with acute respiratory distress syndrome.

  This study is testing if sitting patients up at an angle can help those with Acute Respiratory Distress Syndrome breathe better and avoid complications compared to lying flat.

  Recruiting Centre Hospitalier Régional d'Orléans · Orléans · NCT04472260

• Using a new ventilation method for patients with severe lung injury

  This study is testing a new breathing method for patients with severe lung injury to see if it helps them breathe better and need less medication compared to standard treatments.

  Recruiting Hospital Civil de Guadalajara · Guadalajara, Jalisco · NCT04221737

• Comparing early and late ECMO treatment for severe respiratory failure

  This study is testing whether starting ECMO treatment right away or waiting to see if other treatments work first is better for people with severe respiratory failure caused by ARDS.

  Recruiting University Hospital Tuebingen · Tübingen · NCT04208126

• Registry of extracorporeal life support cases in China

  This study collects information on patients using extracorporeal life support (ECLS) in China to see how well it helps with heart and lung problems over time.

  Recruiting Beijing Anzhen Hospital · Beijing, Beijing Municipality · NCT04158479

• Observing recovery from weakness after severe respiratory and cardiac failure

  This study looks at how people who had severe breathing and heart problems recover from weakness after being in intensive care and on a special life-support machine, to see what helps or hinders their recovery.

  Recruiting Barts & The London NHS Trust · London · NCT03753412

• High-frequency oscillatory ventilation versus conventional mechanical ventilation for very preterm infants with perinatal ARDS

  This trial will test whether high-frequency oscillatory ventilation helps very preterm infants with perinatal ARDS breathe better and reduce lung complications compared with standard mechanical ventilation.

  Recruiting Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · Chongqing, Chongqing Municipality · NCT03736707

• Effects of music therapy on ICU patients on mechanical ventilation

  This study is testing if live music therapy can help ICU patients on mechanical ventilation breathe easier and recover faster.

  Recruiting at 3 sites Icahn School of Medicine at Mount Sinai · New York, New York and 2 other locations · NCT03642002

NIH-funded research (newest 40 of 45)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Identifying ARDS patients who may benefit from paralytics guided by high-frequency clinical data

  This grant aims to help doctors figure out which adults with ARDS are most likely to benefit from paralytic medications using detailed bedside data and electronic health records.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11432547

• Resilience endotypes and early ARDS detection using biomarkers and AI

  A Duke University team is using biomarkers and smart data analysis to detect ARDS early and uncover patterns that predict how patients recover.

  NIH research Duke University · Durham, United States · NIH-11416345

• PAR1’s role in lung lymphatics and a new therapy approach for ARDS

  This grant explores how the thrombin receptor PAR1 affects lung lymphatics to understand and ultimately reduce lung injury in ARDS patients.

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-11412416

• Dead space and inhaled nitric oxide in pediatric ARDS

  This project looks at whether measuring dead space and using inhaled nitric oxide can help improve outcomes for children with acute respiratory distress syndrome.

  NIH research Children's Hospital of Los Angeles · Los Angeles, United States · NIH-11411416

• Immune, hormone, and muscle energy links to recovery after ARDS

  This project looks at why some ARDS survivors have ongoing weakness and how immune, hormone, and muscle energy factors might influence recovery.</n>

  NIH research Columbia University Health Sciences · New York, United States · NIH-11402596

• Understanding why some people with severe lung injury get worse and how to tailor therapy

  A patient-focused program that looks at why people develop sepsis-associated ARDS and how their bodies respond, with the goal of guiding better, personalized treatments.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11401781

• Imaging the Pulmonary Circulation to Personalize ARDS Care

  A patient-focused look at using advanced imaging to understand lung blood flow in ARDS so doctors can tailor treatments.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11385479

• Advanced methods to interpret ARDS trials with modern statistics

  Aims to reanalyze past ARDS trials using Bayesian and machine-learning methods to better identify treatments that help patients with acute respiratory failure.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11324920

• Great Lakes ARDS, Pneumonia & Sepsis Patient Registry Network

  A large multi-hospital effort will enroll and deeply profile adults with ARDS, pneumonia, or sepsis to understand why these conditions vary so much and to guide better trials and treatments.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11321086

• MicroRNA control of lung inflammation in ARDS

  Researchers aim to use a small genetic regulator called miR-147 in immune cells to calm harmful lung inflammation in adults with ARDS.

  NIH research University of Texas Hlth Sci Ctr Houston · Houston, United States · NIH-11317031

• Exploring how blood vessel damage affects breathing difficulties in patients with ARDS

  This study is looking at how damage to blood vessels affects the seriousness of lung problems in people with Acute Respiratory Distress Syndrome (ARDS), and it hopes to find clues in the blood that can help doctors give better, more tailored treatments to patients.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11271544

• Breath-based point-of-care test to diagnose and monitor acute respiratory distress syndrome

  A small bedside breath analyzer will look for chemical patterns in exhaled air to detect and track ARDS in adults.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11263626

• Steroid treatment strategies for adults with ARDS

  This project uses large ICU medical records to compare different steroid timing and dosing approaches for adults with acute respiratory distress syndrome to learn which approaches may work best.

  NIH research Massachusetts Institute of Technology · Cambridge, United States · NIH-11258563

• Using lung dead space and inhaled nitric oxide to guide care for children with ARDS

  Seeing if measuring lung 'dead space' and using inhaled nitric oxide can help doctors treat children with acute respiratory distress syndrome (ARDS).

  NIH research Children's Hospital of Los Angeles · Los Angeles, United States · NIH-11195527

• Why some people don't regain strength after ARDS

  This project looks at whether lasting immune, hormone, and muscle energy problems explain why some adults who survived ARDS stay weak after leaving the hospital.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11184324

• Why some people get ARDS and respond differently to treatment

  This project looks at blood and genetic markers in adults with sepsis-related ARDS to find patterns that could guide different treatments.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11146722

• Imaging lung blood flow to personalize ARDS care

  This project uses advanced imaging to map blood flow in the lungs of people with ARDS so doctors can better target treatments.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11145964

• Dry powder lung surfactant aerosol for people with low oxygen or ARDS on breathing support

  This project is creating a dry powder lung surfactant you could inhale to help adults with low oxygen or ARDS who are on oxygen, noninvasive breathing support, or ventilators.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11145634

• New treatments for severe lung inflammation in older adults

  This study is working on new medications to help people with Acute Respiratory Distress Syndrome (ARDS), especially those who have had respiratory infections like COVID-19, by creating drugs that can reduce harmful inflammation in the lungs while keeping the good stuff intact.

  NIH research Baltimore VA Medical Center · Baltimore, United States · NIH-11098473

• Improving treatments for acute respiratory distress syndrome using advanced statistical methods

  This study is looking at past clinical trial data to find new and better treatments for people with acute respiratory distress syndrome (ARDS) by using advanced techniques, so we can help patients get the care they need.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11092829

• Investigating the causes and treatments of Acute Respiratory Distress Syndrome, pneumonia, and sepsis.

  This study is looking at how Acute Respiratory Distress Syndrome (ARDS), pneumonia, and sepsis are connected, and it aims to help at least 1,000 patients by collecting health information and samples to find better, personalized treatments for these serious conditions over the next six years.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11085978

• Understanding how heart problems affect children with severe lung issues.

  This study is looking at how heart problems, like pulmonary hypertension and right ventricular dysfunction, affect children with acute respiratory distress syndrome (ARDS), to better understand their health and improve treatment for these kids.

  NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-11065521

• Understanding the genetics of acute respiratory distress syndrome (ARDS)

  This study is looking at how our genes might affect how people with acute respiratory distress syndrome (ARDS) respond to the condition, so we can better understand it and find more effective treatments for those who are critically ill.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11061058

• Using existing data to improve steroid treatments for patients with severe lung injury.

  This study is looking at how we can use information from past patients with acute respiratory distress syndrome (ARDS) to find better treatment options that fit each person's needs, especially after what we learned during the COVID pandemic.

  NIH research Massachusetts Institute of Technology · Cambridge, United States · NIH-11045349

• Improving outcomes for adults with ARDS by learning from nurses at top hospitals

  This project explores how nursing staff, resources, and care practices in hospitals relate to survival and readmission for adults with acute respiratory distress syndrome (ARDS).

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11044193

• Developing a new dry powder aerosol to help patients with severe breathing problems

  This study is testing a new dry powder treatment that can be turned into a mist to help people with breathing problems like hypoxemia or ARDS, and it aims to see if this treatment can reduce lung inflammation and work even better when combined with another medicine.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11020319

• Investigating how specific microRNAs can reduce lung inflammation in acute respiratory distress syndrome.

  This study is looking at how a tiny molecule called microRNA-147 can help control lung inflammation in people with acute respiratory distress syndrome (ARDS), with the goal of finding new ways to reduce this inflammation and improve treatment for patients.

  NIH research University of Texas Hlth Sci Ctr Houston · Houston, United States · NIH-11014421

• Exploring how blood vessel damage affects breathing difficulties in patients with acute respiratory distress syndrome.

  This study is looking at how damage to blood vessels affects breathing problems in people with acute respiratory distress syndrome (ARDS) and aims to find better ways to treat this serious condition by checking certain blood markers.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11004968

• A device to diagnose and monitor acute respiratory distress syndrome using breath analysis

  This study is testing a small, portable device that can analyze your breath to help doctors diagnose and keep track of acute respiratory distress syndrome (ARDS) by looking for specific chemicals in your breath.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11004101

• Improving treatment for Acute Respiratory Distress Syndrome using advanced imaging techniques

  This study is looking at how blood flow in the lungs works for people with Acute Respiratory Distress Syndrome (ARDS), especially those affected by COVID-19, using special imaging techniques to help doctors find better ways to treat them.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-10978564

• New treatment for severe lung complications from sepsis

  This study is testing a new inhaled medication to help people with acute respiratory distress syndrome (ARDS) caused by sepsis, aiming to reduce lung inflammation and improve breathing for those at risk.

  NIH research Cmtx Biotech, INC. · Kings Park, United States · NIH-10950503

• Targeting a key immune protein to improve treatment for acute respiratory distress syndrome.

  This study is looking at how a special treatment can help people with acute respiratory distress syndrome (ARDS) by blocking a protein called CD14, which might help calm down the overactive immune response in their lungs, especially for those with COVID-19.

  NIH research University of Washington · Seattle, United States · NIH-10948018

• Investigating factors affecting recovery in survivors of Acute Respiratory Distress Syndrome

  This study is looking at why some people who survived severe lung issues from COVID-19 still feel weak and have trouble recovering, and it’s for ARDS survivors who want to help find ways to improve their recovery over the next year.

  NIH research Columbia University Health Sciences · New York, United States · NIH-10917148

• Identifying and preventing severe lung complications after stem cell transplants

  This study is looking to help patients who are getting a stem cell transplant by finding ways to predict and prevent a serious lung problem called acute respiratory distress syndrome (ARDS), so they can have a smoother recovery.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-10909914

• How aging and inflammation affect outcomes in severe lung disease

  This study is looking at how aging and inflammation affect the severity of Acute Respiratory Distress Syndrome (ARDS) in older adults, with the goal of finding better treatments that fit each person's unique health profile.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-10906138

• Improving the use of stomach positioning for patients with severe respiratory issues

  This study is looking for ways to help doctors use a special treatment called prone positioning more often for patients with severe breathing problems from COVID-19, so they can get better care in the hospital.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-10899599

• Understanding how individual differences affect responses to acute respiratory distress syndrome

  This study is looking at how our bodies' immune responses and genetic traits affect the risk of developing acute respiratory distress syndrome (ARDS) during serious illnesses like sepsis and COVID-19, with the hope of finding better treatments to help patients recover and survive.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-10894801

• Understanding immune checkpoints in acute respiratory distress syndrome

  This study is looking at how certain immune pathways might affect people with acute respiratory distress syndrome (ARDS) to help create better treatment options and improve care for patients who need long-term breathing support.

  NIH research Benaroya Research Inst at Virginia Mason · Seattle, United States · NIH-10871697

• Developing a new dry powder aerosol treatment for lung issues in patients with respiratory distress

  This study is working on a new way to help people with serious breathing problems, like low oxygen levels or acute respiratory distress syndrome, by creating a dry powder that can be easily inhaled instead of using liquid treatments that can be harder to give.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-10863857

• Investigating the use of inhaled nitric oxide to improve outcomes in children with acute respiratory distress syndrome.

  This study is looking at ways to help doctors better understand and treat children with a serious lung condition called ARDS by finding clues in their routine health data, so they can figure out which kids might respond best to certain treatments and ultimately help them recover better.

  NIH research Children's Hospital of Los Angeles · Los Angeles, United States · NIH-10859725

Related topics

Quick answers

How many Acute Respiratory Distress Syndrome clinical trials are recruiting right now?

58, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 29 countries. The most sites are in China (15 trials), United States (13 trials), France (12 trials), Germany (5 trials), Italy (5 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 7, Phase 3: 3, Phase 1/2: 2, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →