Investigating the causes and treatments of Acute Respiratory Distress Syndrome, pneumonia, and sepsis.

Great Lakes Clinical Center of the Acute Respiratory Distress Syndrome, Pneumonia and Sepsis (APS) Consortium

NIH-funded research University of Michigan at Ann Arbor · NIH-11085978

This study is looking at how Acute Respiratory Distress Syndrome (ARDS), pneumonia, and sepsis are connected, and it aims to help at least 1,000 patients by collecting health information and samples to find better, personalized treatments for these serious conditions over the next six years.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-11085978 on NIH RePORTER

What this research studies

This research focuses on understanding the complex relationships between Acute Respiratory Distress Syndrome (ARDS), pneumonia, and sepsis, which are serious health conditions that often occur together. The study will enroll at least 1,000 patients over six years, collecting clinical data and biological samples such as blood and swabs to analyze the different characteristics of these conditions. By examining these samples and data, researchers aim to identify specific patient profiles that could lead to more effective treatments tailored to individual needs. Patients will be followed up at multiple time points to gather long-term health information.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults diagnosed with Acute Respiratory Distress Syndrome, pneumonia, or sepsis.

Not a fit: Patients with chronic respiratory conditions unrelated to ARDS, pneumonia, or sepsis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies and outcomes for patients suffering from ARDS, pneumonia, and sepsis.

How similar studies have performed: Previous research has shown promise in understanding ARDS and related conditions, but this approach aims to deepen insights into their biological diversity, making it a novel endeavor.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acute Respiratory Distress SyndromeAdult Respiratory Distress Syndrome
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.