Investigating the use of inhaled nitric oxide to improve outcomes in children with acute respiratory distress syndrome.
Dead Space and Inhaled Nitric Oxide in Pediatric Acute Respiratory Distress Syndrome
This study is looking at ways to help doctors better understand and treat children with a serious lung condition called ARDS by finding clues in their routine health data, so they can figure out which kids might respond best to certain treatments and ultimately help them recover better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hospital of Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10859725 on NIH RePORTER |
What this research studies
This research focuses on pediatric acute respiratory distress syndrome (ARDS), a serious condition affecting children that has a high mortality rate. The study aims to identify biological markers that can help differentiate between patients who may benefit from specific therapies and those who may not. By analyzing routine patient monitoring data, such as capnography and blood gases, the researchers will estimate dead space in the lungs, which may provide insights into the underlying causes of ARDS and guide treatment decisions. The ultimate goal is to improve survival rates and treatment effectiveness for children suffering from this condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who are diagnosed with acute respiratory distress syndrome.
Not a fit: Patients who do not have acute respiratory distress syndrome or are older than 11 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatments for children with ARDS, potentially reducing mortality rates.
How similar studies have performed: Previous studies have shown promise in using biological markers to guide treatment in ARDS, but this specific approach focusing on dead space is relatively novel.
Where this research is happening
Los Angeles, United States
- Children's Hospital of Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Bhalla, Anoopindar — Children's Hospital of Los Angeles
- Study coordinator: Bhalla, Anoopindar
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.