How aging and inflammation affect outcomes in severe lung disease
The Association Between Aging, Inflammation, and Clinical Outcomes in Acute Respiratory Distress Syndrome
This study is looking at how aging and inflammation affect the severity of Acute Respiratory Distress Syndrome (ARDS) in older adults, with the goal of finding better treatments that fit each person's unique health profile.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10906138 on NIH RePORTER |
What this research studies
This research investigates the relationship between aging, inflammation, and clinical outcomes in patients suffering from Acute Respiratory Distress Syndrome (ARDS). It focuses on understanding how biological age and inflammatory responses impact the severity of ARDS, particularly in older adults. The study will analyze protein biomarkers and explore different subphenotypes of ARDS to identify potential new treatment approaches. By examining these factors, the research aims to improve patient outcomes and tailor therapies based on individual biological profiles.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults diagnosed with Acute Respiratory Distress Syndrome.
Not a fit: Patients who are younger and do not have ARDS may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for older patients with ARDS, potentially improving survival rates and quality of life.
How similar studies have performed: Previous research has shown promising results in understanding the role of inflammation and aging in various diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
Baltimore, United States
- University of Maryland Baltimore — Baltimore, United States (Active)
Researchers
- Principal investigator: Levine, Andrea — University of Maryland Baltimore
- Study coordinator: Levine, Andrea
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.