Optimizing blood flow in patients on veno-venous ECMO

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to measure the recirculation fraction (Rf) of blood in patients with acute respiratory distress syndrome (ARDS) undergoing veno-venous ECMO. By utilizing an ultrasound dilution technique, the study will assess how optimizing ECMO blood flow based on Rf measurements can improve systemic oxygenation. The goal is to reduce ECMO blood flow without compromising patient oxygenation, potentially enhancing treatment outcomes for those on ECMO support.

Why it matters

Who can join: the full rules

Patients aged 18 years or older requiring veno-venous ECMO for treatment of refractory hypoxemia in ARDS.

Where it's running

• Charité - Universitätsmedizin Berlin, Campus Virchow Klinikum
  Berlin, Germany Recruiting

Study contacts

• Principal investigator: Martin Russ, Dr. med. — Charite University Hospital Berlin
• Study coordinator: Steffen Weber-Carstens, Prof. Dr. med.
• Email: steffen.weber-carstens@charite.de
• Phone: 0049-30450651005

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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  This study is trying to see if measuring the power of breathing machines can help doctors predict how well patients with severe lung problems on ECMO will do and improve their treatment.

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• Full-Course ECMO Pathway for Moderate-to-Severe ARDS

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• Height measurement methods to guide ventilator settings in ARDS

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  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT07595926

• Corticosteroids for a hyperinflammatory state in critical illness

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  Recruiting Phase 2 Peking Union Medical College Hospital · Beijing, Beijing Municipality · NCT07511582

• Right‑heart function and heart–lung interaction during ARDS with mechanical ventilation

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  Recruiting Bicetre Hospital · Le Kremlin-Bicêtre · NCT07450846

• Umbilical‑cord mesenchymal stem cell and secretome therapy for severe ARDS

  This trial tests whether IV umbilical‑cord mesenchymal stem cells, alone or with secretome, help adults with severe ARDS recover lung function and reduce inflammation.

  Recruiting Phase 1/2 PT. Prodia Stem Cell Indonesia · Jakarta Pusat, DKI Jakarta · NCT07439848

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.