Understanding the genetics of acute respiratory distress syndrome (ARDS)
Tissue-specific functional genomics in the acute respiratory distress syndrome
This study is looking at how our genes might affect how people with acute respiratory distress syndrome (ARDS) respond to the condition, so we can better understand it and find more effective treatments for those who are critically ill.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-11061058 on NIH RePORTER |
What this research studies
This research investigates the genetic factors that contribute to acute respiratory distress syndrome (ARDS), a serious condition affecting many adults. By analyzing large-scale electronic health records and DNA samples, the study aims to identify specific genetic variations that influence how patients respond to ARDS. The research will focus on gene expression in lung tissues and immune cells from critically ill adults, helping to categorize different subtypes of ARDS. This approach could lead to better predictions of disease risk and the development of targeted therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are critically ill adults who have been diagnosed with acute respiratory distress syndrome.
Not a fit: Patients who do not have ARDS or are under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized treatment options for patients with ARDS, improving their chances of recovery.
How similar studies have performed: Previous research has shown promise in using genetic analysis to understand complex diseases, indicating that this approach could yield valuable insights for ARDS.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Kerchberger, Vern Eric — Vanderbilt University Medical Center
- Study coordinator: Kerchberger, Vern Eric
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.