Condition

Extracorporeal Membrane Oxygenation clinical trials and research

• 12Clinical trials
• 7NIH research projects
• 10Countries

Newest Extracorporeal Membrane Oxygenation clinical trials

All recruiting trials (12)

• Impact of lower vasopressor use on survival in patients with heart failure on ECMO

  This study is testing if using less vasopressor medication can help adults with heart failure on ECMO survive better over 30 days.

  Recruiting Beijing Anzhen Hospital · Beijing, Beijing Municipality · NCT06862700

• Nebulized amikacin for VA-ECMO–associated pneumonia in adults

  We’re testing whether giving amikacin as a nebulized inhaled medicine helps clear gram-negative pneumonia in adults on VA-ECMO who are also on mechanical ventilation.

  Recruiting Phase 2 Assistance Publique - Hôpitaux de Paris · Paris · NCT06602557

• Comparing blood transfusion thresholds in patients on ECMO

  This study tests whether giving fewer blood transfusions is safe and effective for adults on ECMO compared to giving more transfusions.

  Recruiting at 13 sites Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Vienna, State of Vienna and 13 other locations · NCT06560164

• Evaluating outcomes and quality of life for patients on ECMO

  This study is trying to see how well patients do and how their quality of life is after receiving ECMO therapy for serious breathing or heart problems.

  Recruiting Heinrich-Heine University, Duesseldorf · Düsseldorf, North Rhine-Westphalia · NCT06400797

• Evaluating the impact of transpulmonary mechanical power on patients with severe ARDS on ECMO

  This study is trying to see if measuring the power of breathing machines can help doctors predict how well patients with severe lung problems on ECMO will do and improve their treatment.

  Recruiting Beijing Chao Yang Hospital · Beijing, Beijing Municipality · NCT06062212

• Comparing individualized and conventional blood transfusion strategies during ECMO for heart failure

  This study is testing whether a personalized blood transfusion approach during heart support treatment can help patients use less blood and have better outcomes compared to the standard method.

  Recruiting at 4 sites Phase 1 University Hospital, Lille · Lille, NORD and 3 other locations · NCT05699005

• Testing inhaled hydrogen gas for cardiac arrest treatment

  This study is testing if breathing in hydrogen gas can help improve recovery for patients who have had a cardiac arrest and are receiving special life-saving treatment.

  Recruiting Phase 1 Boston Children's Hospital · Washington D.C., District of Columbia and 3 other locations · NCT05574296

• Using ECMO to help patients with severe respiratory failure recover

  This study is testing if using a special breathing machine called ECMO along with regular ventilation can help patients with severe breathing problems recover faster and spend less time in intensive care.

  Recruiting at 6 sites Australian and New Zealand Intensive Care Research Centre · Darlinghurst, New South Wales and 6 other locations · NCT05562505

• Comparing revascularization strategies for heart attack patients with cardiogenic shock

  This study is testing whether treating multiple blocked heart arteries right away helps heart attack patients in shock feel better compared to just fixing the main blockage.

  Recruiting Phase 4 Samsung Medical Center · Seoul · NCT05527717

• Optimizing blood flow in patients on veno-venous ECMO

  This study is testing if adjusting blood flow during ECMO treatment can help patients with severe breathing problems get better oxygen without needing as much blood flow.

  Recruiting Charite University, Berlin, Germany · Berlin · NCT04754854

• ECMO treatment for children in China over the last decade

  This study looks at how ECMO treatment has been used for sick children in hospitals across China over the last ten years to see what has changed and what works best.

  Recruiting Children's Hospital of Fudan University · Shanghai, Shanghai Municipality · NCT04709432

• Identifying factors that predict survival and neurological outcomes in patients treated with E-CPR.

  This study looks at patients who received ECMO treatment after a cardiac arrest to see what factors can help predict their survival and brain recovery.

  Recruiting Sahlgrenska University Hospital · Gothenburg · NCT04198792

NIH-funded research (7)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Diffuse optical brain imaging to monitor ECMO patients at bedside

  A patient-friendly look at using a safe, portable brain-imaging method to monitor children and adults on ECMO for brain health right at the bedside.

  NIH research Washington University · Saint Louis, United States · NIH-11465648

• Searching for inherited genetic causes of ME/CFS

  Researchers will sequence the genomes of relatives with ME/CFS to find rare inherited genetic changes that might cause the illness.

  NIH research University of Rochester · Rochester, United States · NIH-11232343

• Monitoring brain health in patients on life support for heart or lung failure

  This study is looking at new ways to safely check how your brain is doing while you're on ECMO, a life-saving treatment for serious heart or lung problems, to help doctors make better decisions and protect your brain health during your care.

  NIH research University of Rochester · Rochester, United States · NIH-11005405

• Developing a new pump for pediatric heart support

  This study is working on a new heart support pump specifically made for babies and young children, aiming to keep their blood safe while helping them breathe better.

  NIH research Mira Medical, LLC · Potomac, United States · NIH-11005336

• Investigating the effects of blood clots and oxygen levels during heart support treatment.

  This study is looking at how the heart-lung machine used in severe heart failure treatment might cause blood clots and brain injuries, with the goal of finding ways to help patients have better brain health during and after their treatment.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11004087

• Understanding how VA-ECMO affects heart function in heart attacks

  This study is looking at how a special heart-lung machine called VA-ECMO affects heart function in people having a severe heart attack, with the hope of finding better ways to help patients recover.

  NIH research Tufts Medical Center · Boston, United States · NIH-10866075

• Identifying brain injury markers in critically ill children on ECMO.

  This study is looking to find new ways to check for brain injuries in kids who are getting a special treatment called ECMO for serious heart and lung problems, so doctors can better protect their brains and help them recover.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-10545733

Related topics

Quick answers

How many Extracorporeal Membrane Oxygenation clinical trials are recruiting right now?

12, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 10 countries. The most sites are in China (3 trials), Germany (3 trials), Sweden (2 trials), France (2 trials), South Korea (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 2, Phase 4: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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