Height measurement methods to guide ventilator settings in ARDS
Official title: Height Measurement Procedures Influence the Risk of Ventilator-induced Lung Injury in ARDS
Run by Centre Hospitalier Universitaire, Amiens · NCT07595926 · Data updated 2026-11-12
We’re testing whether more precise height measurements change how researchers set lung-protective tidal volumes in adults with ARDS who are on a ventilator.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 39 (estimated) |
| Sponsor | Centre Hospitalier Universitaire, Amiens Academic / other |
| Locations | 1 site (Amiens) |
| Status | Recruiting |
| Started | May 20, 2026 |
| Main results expected | May 2028 |
| Study ends | May 2028 |
| Registry record updated | July 6, 2026 |
| Trial ID | NCT07595926 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with ARDS on mechanical ventilation, sedated and paralyzed, within 48 hours of ARDS diagnosis, able to provide consent or via surrogate.
✕Probably not a fit
Patients for whom height cannot be measured by the reference method or who do not require changes to VT based on PBW.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In ARDS, accurate height is used to calculate predicted body weight for safe tidal volumes. This study tests alternative height measurement methods to see if they affect ventilation parameters and potentially reduce ventilator-induced lung injury. Participants are adults with ARDS on a fixed-volume ventilator, whose height will be measured using methods beyond standard tape or visual estimate. The trial focuses on whether improved height measurement changes lung stress and patient outcomes. The study uses an interventional approach where height measurement technique is applied to inform VT settings.
Why it matters
Potential benefit: If successful, more accurate height measurement could lead to safer, more effective ventilation for people with ARDS.
How similar studies have gone: Previous work suggests measurement accuracy affects PBW calculations, but the impact on lung mechanics in ARDS has not been fully explored.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patient * Mechanical ventilation on volumetric mode * Sedated and curarized patient * Diagnosis of ARDS according to the Berlin criteria * Diagnosis of ARDS \< 48 hours * Signed informed consent * Affiliation with a social security or health insurance scheme Exclusion Criteria: * Patient opposing the use of his/her data for research purposes. * Contraindication to placement of an esophageal balloon catheter (e.g., esophageal fistula, esophageal varices). * Contraindication to strict supine positioning for height measurement (e.g., proven or suspected intracranial hypertension with intracranial pressure \>18 mmHg). * Impossibility of measuring height with the reference method (stadiometer) due to deformity or amputation of both lower limbs. * Patient under guardianship or curatorship, or deprived of liberty. * Pregnant or postpartum patient, or patient currently breastfeeding.
Where it's running
-
CHU Amiens
Amiens, France Recruiting
Study contacts
- Study coordinator: Clément BRAULT, MD
- Email: brault.clement@chu-amiens.fr
- Phone: 33+322087831
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.