Improving treatment for Acute Respiratory Distress Syndrome using advanced imaging techniques

Who could benefit from this research

What this research studies

This research focuses on understanding how blood flow in the lungs is affected in patients with Acute Respiratory Distress Syndrome (ARDS), a serious condition that can lead to death, especially in cases related to COVID-19. By using advanced imaging techniques like dynamic contrast-enhanced and dual-energy CT scans, the study aims to visualize and analyze lung perfusion in real-time. This information could help tailor treatments more effectively for patients suffering from ARDS, potentially improving their outcomes. The research will involve both clinical assessments and advanced imaging to gather comprehensive data on lung function and blood flow.

Why it matters

Where this research is happening

• Massachusetts General Hospital
  Boston, United States Active

Researchers

• Principal investigator: Cereda, Maurizio Franco — Massachusetts General Hospital
• Study coordinator: Cereda, Maurizio Franco

Related research

Other NIH-funded projects on the same topics.

• Identifying ARDS patients who may benefit from paralytics guided by high-frequency clinical data

  This grant aims to help doctors figure out which adults with ARDS are most likely to benefit from paralytic medications using detailed bedside data and electronic health records.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11432547

• Resilience endotypes and early ARDS detection using biomarkers and AI

  A Duke University team is using biomarkers and smart data analysis to detect ARDS early and uncover patterns that predict how patients recover.

  NIH research Duke University · Durham, United States · NIH-11416345

• PAR1’s role in lung lymphatics and a new therapy approach for ARDS

  This grant explores how the thrombin receptor PAR1 affects lung lymphatics to understand and ultimately reduce lung injury in ARDS patients.

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-11412416

• Dead space and inhaled nitric oxide in pediatric ARDS

  This project looks at whether measuring dead space and using inhaled nitric oxide can help improve outcomes for children with acute respiratory distress syndrome.

  NIH research Children's Hospital of Los Angeles · Los Angeles, United States · NIH-11411416

• Immune, hormone, and muscle energy links to recovery after ARDS

  This project looks at why some ARDS survivors have ongoing weakness and how immune, hormone, and muscle energy factors might influence recovery.</n>

  NIH research Columbia University Health Sciences · New York, United States · NIH-11402596

• Understanding why some people with severe lung injury get worse and how to tailor therapy

  A patient-focused program that looks at why people develop sepsis-associated ARDS and how their bodies respond, with the goal of guiding better, personalized treatments.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11401781

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.