Condition

ARDS (Acute Respiratory Distress Syndrome) clinical trials and research

• 24Clinical trials
• 1New in 30 days
• 10Countries

Newest ARDS (Acute Respiratory Distress Syndrome) clinical trials

All recruiting trials (24)

• Pulse Wave vs Saline Bolus EIT to measure lung perfusion in ARDS

  This study tests whether pulse wave EIT or saline bolus EIT can best show lung blood flow in ARDS patients on mechanical ventilation.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07908368

• Biorepository and endotyping study for ARDS patients

  This observational study tests whether creating a centralized ARDS biorepository and data set can help develop endotype and treatment-prediction tools for adults with ARDS.

  Recruiting Prenosis, Inc. · Urbana, Illinois · NCT07675265

• BAL balance: ARDS through lung lavage and imaging to find different ARDS types

  This study tests how bronchoalveolar lavage fluid and chest CT imaging can reveal different ARDS subtypes in adults with ARDS or severe pneumonia in the ICU.

  Recruiting Medical University of Vienna · Vienna, State of Vienna · NCT07633366

• Titrating PEEP in ARDS: Manual chest compression vs. electrical impedance tomography

  In adults with ARDS on mechanical ventilation, the study tests whether a simple manual chest compression method can set the right PEEP as well as electrical impedance tomography (EIT).

  Recruiting at 2 sites Centre Hospitalier Saint Joseph Saint Luc de Lyon · Créteil and 1 other locations · NCT07623590

• Individualized PEEP Titration in ARDS Based on Lung Recruitment Potential

  This pilot study tests two personalized PEEP strategies in adults with ARDS to see which approach better supports breathing mechanics by using a recruitment potential measure.

  Recruiting Hospital Dr. Franco Ravera Zunino · Rancagua, Región del Libertador General Bernardo O’Higgins · NCT07603310

• Single-dose inhaled rh-KGF-2 for ARDS in adults

  This trial tests whether a single inhaled dose of rh-KGF-2 helps adults with ARDS who are on ventilators, using three dose levels to see which is safest and potentially most effective.

  Recruiting Early Phase 1 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07558538

• HT31-1 for ARDS: a first-in-human test of a monoclonal antibody

  This early study tests whether HT31-1, a monoclonal antibody, is safe and how it behaves in the body in healthy adults, with a plan to move into ARDS patients later.

  Recruiting Phase 1 HTIC, Inc · Richmond, Virginia and 1 other locations · NCT07449572

• EIT-guided Ventilation Strategy in ARDS

  A multi-center randomized trial tests whether using bedside electrical impedance tomography to guide ventilation, including PEEP and prone positioning, improves outcomes for adults with ARDS compared with standard lung-protective ventilation.

  Recruiting Peking Union Medical College Hospital · Beijing, Beijing Municipality · NCT07309783

• Real-time, algorithm-driven ventilation feedback to improve lung protection in ARDS

  This study tests whether a cloud-based, real-time ventilation feedback system helps doctors deliver more lung-protective ventilation to adults with ARDS on invasive mechanical ventilation.

  Recruiting Peking Union Medical College Hospital · Qujing, Yunnan · NCT07307066

• Impact of Low vs High PEEP on Diaphragm and Lung Function in Mechanically Ventilated Patients

  This study tests whether different levels of PEEP (low, medium, high) change diaphragm effort and ventilation effectiveness in adults on pressure-support ventilation in the ICU.

  Recruiting Vastra Gotaland Region · Gothenburg, Västra Götaland County and 1 other locations · NCT07188038

• Real-world look at severe respiratory failure (ARDS)

  This project will collect real-world data on adults at high risk for ARDS to see which clinical factors predict worse outcomes.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07165717

• Using patient blood cells to test whether PIP-2 calms immune activation in ARDS

  This project will test whether a drug called PIP-2 can calm overactive immune cells taken from people with ARDS.

  Recruiting University of Pennsylvania · Philadelphia, Pennsylvania · NCT07125079

• Monitoring lung changes from prone positioning in ARDS with 3D electrical impedance tomography

  This will see if turning adults on ventilators with ARDS onto their stomachs changes lung air distribution and blood flow as measured by 3D electrical impedance tomography, and it will compare 3D to 2D EIT for monitoring.

  Recruiting Peking Union Medical College Hospital · Beijing, Beijing Municipality · NCT07083973

• EIT-guided PEEP for ARDS patients with higher lung recruitability

  This trial tests whether using bedside electrical impedance tomography (EIT) to set PEEP helps adults with moderate-to-severe ARDS who show higher lung recruitability.

  Recruiting at 2 sites Southeast University, China · Hefei, Anhui and 16 other locations · NCT06990477

• Measuring lung stretching with ultrasound in ventilated patients

  This study is testing a new ultrasound method to see how much the lining of the lungs stretches during breathing in ICU patients on ventilators, to help doctors adjust the machines safely and reduce lung injury.

  Recruiting First Affiliated Hospital of Wannan Medical College · Wuhu, Anhui · NCT06911450

• Using breathing‑drive measurements to decide when to stop veno‑venous ECMO

  This study will test whether measuring ventilator drive (P0.1) and esophageal pressure swings to guide decannulation helps adult ARDS patients on veno‑venous ECMO come off ECMO sooner and safely.

  Recruiting at 4 sites Assistance Publique Hopitaux De Marseille · Lyon and 3 other locations · NCT06876415

• Comparing low tidal volume and airway pressure release ventilation for ARDS patients

  This study tests which breathing method, low tidal volume or airway pressure release ventilation, helps adults with Acute Respiratory Distress Syndrome breathe better and feel safer while on a ventilator.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06790875

• Evaluating esophageal pressure measurements in ARDS patients during breathing trials

  This study is testing if measuring pressure in the esophagus during breathing trials can help doctors predict if patients with ARDS on ventilators can safely be taken off the machine.

  Recruiting Sapporo Medical University · Sapporo, Hokkaido · NCT06734988

• Innovative therapies for Acute Respiratory Distress Syndrome

  This study is testing new treatments for adults in the hospital with Acute Respiratory Distress Syndrome to see if they can improve breathing and overall recovery compared to a placebo.

  Recruiting at 27 sites Phase 2 PPD Development, LP · Birmingham, Alabama and 40 other locations · NCT06703073

• Evaluating vilobelimab for treating Acute Respiratory Distress Syndrome

  This study is testing if vilobelimab can help hospitalized adults with Acute Respiratory Distress Syndrome feel better and improve their chances of recovery compared to a placebo.

  Recruiting at 28 sites Phase 2 PPD Development, LP · Birmingham, Alabama and 40 other locations · NCT06701682

• Evaluating a new treatment for Acute Respiratory Distress Syndrome

  This study is testing a new treatment called paridiprubart to see if it can help hospitalized adults with Acute Respiratory Distress Syndrome breathe better and improve their chances of recovery.

  Recruiting at 28 sites Phase 2 PPD Development, LP · Birmingham, Alabama and 40 other locations · NCT06701669

• Evaluating Bevacizumab for Acute Respiratory Distress Syndrome

  This study is testing whether a medication called bevacizumab can help hospitalized adults with Acute Respiratory Distress Syndrome breathe better and improve their chances of recovery.

  Recruiting at 28 sites Phase 2 PPD Development, LP · Birmingham, Alabama and 40 other locations · NCT06701656

• Effects of Lung Impedance Tomography on Breathing in ARDS Patients

  This study tests if using a special lung monitoring technique can improve breathing and blood flow in patients with acute respiratory distress syndrome by adjusting their ventilation settings.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06696638

• RECOMMEND platform testing interventions for adults receiving ECMO

  This platform tests whether different treatments, such as liberal versus restrictive red blood cell transfusion strategies, help adults on ECMO survive and need less organ support and hospital resources by day 28.

  Recruiting Phase 3 Australian and New Zealand Intensive Care Research Centre · Camperdown, New South Wales and 2 other locations · NCT06526533

Related topics

Quick answers

How many ARDS (Acute Respiratory Distress Syndrome) clinical trials are recruiting right now?

24, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 10 countries. The most sites are in China (10 trials), United States (7 trials), France (2 trials), Australia (1 trial), South Korea (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 3: 1, Phase 1: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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