Using lung ultrasound to diagnose ARDS in patients on mechanical ventilation

Early Diagnosis of Acute Respiratory Distress Syndrome (ARDS) in Mechanically Ventilated Patient Using Lung Ultrasound Score in Comparison With CT Chest

This study is testing if lung ultrasound can help doctors quickly diagnose ARDS in patients on mechanical ventilation, comparing it to CT scans.

Quick facts

• Study type: Observational
• Enrollment: 20 (estimated)
• Ages: 22 Years to 80 Years
• Sex: All
• Sponsor: Tanta University (Academic / other)
• Drugs / interventions: radiation
• Locations: 1 site (Tanta)
• Trial ID: NCT06971042 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the accuracy of lung ultrasound scoring for the early diagnosis of acute respiratory distress syndrome (ARDS) in patients expected to be mechanically ventilated for more than 24 hours, comparing it with computed tomography (CT) scans. ARDS is a severe lung condition characterized by poor oxygenation and pulmonary infiltrates, often leading to high mortality rates. The study will include patients who meet the Berlin definition of ARDS and will assess the effectiveness of lung ultrasound as a diagnostic tool in this critical setting.

Who should consider this trial

Good fit: Ideal candidates are patients over 21 years old who are expected to be mechanically ventilated for more than 24 hours and suspected of having ARDS.

Not a fit: Patients with pre-existing lung diseases, acute kidney injury, or those who refuse participation may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to earlier and more accurate diagnosis of ARDS, potentially improving patient outcomes.

How similar studies have performed: While lung ultrasound has been explored in various contexts, this specific approach for diagnosing ARDS in mechanically ventilated patients is relatively novel.

Eligibility criteria

Inclusion Criteria:

* Patients aged more than 21 years old of both sexes .
* Patients who are expected to be mechanically ventilated more than 24 h .
* Patients who are suspected to be Acute Respiratory Distress Syndrome according to Berlin definition which consists of clinical criteria and with precipitating factors which starts within 1 week of known insult as in trauma patients with lung contusions.

Exclusion Criteria:

* Patient's first guardian who refuse the inclusion in the study .
* History of pre-existing lung disease ( tumors, interstitial lung diseases)
* In cases of volume overload.
* Patients with acute kidney injuiry or renal failure

Where this trial is running

Tanta

• Tanta university — Tanta, Egypt (Recruiting)

Study contacts

• Principal investigator: Roaa Elshamy, MSc — Tanta University
• Study coordinator: Roaa Elshamy, MSc

Conditions Acute Respiratory Distress Syndrome; Mechanical Ventilation Complication; Computed Tomography