Condition

Mechanical Ventilation Complication clinical trials and research

• 21Clinical trials
• 18Countries

Newest Mechanical Ventilation Complication clinical trials

All recruiting trials (21)

• Controlled versus standard oxygen therapy for ICU COPD with acute exacerbation

  This trial tests whether keeping oxygen levels at 88-92% helps ICU patients with an acute COPD flare more than keeping levels above 94%.

  Recruiting Hôpital Universitaire Taher Sfar · Mahdia, Mahdia Governorate and 1 other locations · NCT07842510

• ClusterVAP: Multicentre Proteomic Endotyping of Ventilator-Associated Pneumonia

  Researchers will test whether proteomic patterns in BAL fluid can identify subgroups of patients with suspected VAP on mechanical ventilation.

  Recruiting at 2 sites Region Skane · Limoges and 3 other locations · NCT07245888

• Using EIT to personalize PEEP during bariatric surgery

  This will test whether using electrical impedance tomography (EIT) to set personalized PEEP during laparoscopic bariatric surgery reduces postoperative lung complications compared with a fixed PEEP of 8 cmH2O in adults with obesity.

  Recruiting Qianfoshan Hospital · Jinan, Shandong · NCT07207772

• How common pain is in adults on mechanical ventilators in intensive care units

  The researchers will measure how often adults on invasive mechanical ventilation in ICUs experience pain and which clinical factors are linked to it.

  Recruiting at 4 sites Centro Universitário Augusto Motta · Rio de Janeiro, Rio de Janeiro and 3 other locations · NCT07182851

• Using lung ultrasound to diagnose ARDS in patients on mechanical ventilation

  This study is testing if lung ultrasound can help doctors quickly diagnose ARDS in patients on mechanical ventilation, comparing it to CT scans.

  Recruiting Tanta University · Tanta · NCT06971042

• Using the Pressure-Muscle Index to avoid excessive ventilator support during pressure support ventilation

  This study will try using a Pressure-Muscle Index to find the right amount of pressure support for adults on mechanical ventilation for acute low-oxygen (hypoxemic) respiratory failure.

  Recruiting Università degli Studi di Trento · Trento, Trento · NCT06921655

• Using EEG to guide sedation and pain relief in ICU patients

  This study tests if using a special device to monitor brain activity can help doctors give the right amount of sedation and pain relief to ICU patients on ventilators, aiming to improve their recovery.

  Recruiting Università degli Studi di Ferrara · Ferrara, Italy and 1 other locations · NCT06769308

• Assessing the safety and effectiveness of remazolam besylate for sedation in critically ill patients on ventilators after surgery

  This study is testing if a new sedative called remazolam besylate is safe and effective for helping critically ill patients on ventilators after surgery, compared to a standard sedative.

  Recruiting Phase 4 Beijing Shijitan Hospital, Capital Medical University · Beijing, Beijing Municipality · NCT06575530

• Using a mechanical cough-assist with optimized settings to reduce mucus in adults on ventilators

  This will test whether using optimized mechanical insufflation-exsufflation (MI-E) settings helps clear wet mucus in adults who are intubated and receiving invasive mechanical ventilation.

  Recruiting Hospital Clinic of Barcelona · Barcelona · NCT06491017

• Comparing VC and PC ventilation effects during laparoscopic gynecologic surgery

  This study is testing whether using volume control or pressure control ventilation during laparoscopic gynecologic surgery can improve breathing and recovery for patients.

  Recruiting Umraniye Education and Research Hospital · Istanbul, Umraniye · NCT06482983

• Evaluating a new sedation protocol for critically ill patients on mechanical ventilation

  This study is testing a new way to provide sedation for critically ill patients on breathing machines to see if it helps them recover better than the usual method.

  Recruiting Siriraj Hospital · Bangkok, Bangkok · NCT06203405

• Improving ICU care through behavioral strategies

  This study is testing two strategies to help ICU staff use better practices for caring for critically ill adults, especially those facing health challenges, to see if it can improve patient recovery and reduce complications.

  Recruiting at 3 sites University of Nebraska · Iowa City, Iowa and 2 other locations · NCT06184945

• Evaluating ventilation practices in children during general anesthesia

  This study looks at how children are helped to breathe during surgery to see if different methods affect their recovery and the chance of complications afterwards.

  Recruiting Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Perth and 3 other locations · NCT06166706

• Investigating sedation methods for patients with Acute Respiratory Distress Syndrome on ventilators

  This study is testing whether using different sedation methods helps patients with Acute Respiratory Distress Syndrome on ventilators breathe better and feel more comfortable in the ICU.

  Recruiting Phase 2/3 Guy's and St Thomas' NHS Foundation Trust · London, London · NCT06014138

• Using ECMO to help patients with severe respiratory failure recover

  This study is testing if using a special breathing machine called ECMO along with regular ventilation can help patients with severe breathing problems recover faster and spend less time in intensive care.

  Recruiting at 6 sites Australian and New Zealand Intensive Care Research Centre · Darlinghurst, New South Wales and 6 other locations · NCT05562505

• Investigating heart function's role in weaning from mechanical ventilation

  This study is testing how heart function affects the ability of critically ill patients on mechanical ventilation to breathe on their own without developing lung problems.

  Recruiting at 3 sites Centre Hospitalier Universitaire de Nice · Dijon and 2 other locations · NCT05226247

• How diaphragm strength changes during and after mechanical ventilation

  This project will try to see how quickly the diaphragm weakens in ICU patients on mechanical ventilation and whether it recovers after they are taken off the ventilator.

  Recruiting RWTH Aachen University · Aachen · NCT05211661

• Impact of Early Mobilization on Diaphragm Thickness in Critically Ill Children

  This study is testing if getting critically ill children moving early while they are on a ventilator can help keep their diaphragm stronger compared to just regular care.

  Recruiting Children's Hospital of Fudan University · Shanghai · NCT04534296

• Comparing two ventilation modes to reduce diaphragm atrophy in intubated patients

  This study is testing if using a different breathing support method can help intubated patients avoid diaphragm problems and spend less time on a ventilator.

  Recruiting University of Chicago · Chicago, Illinois and 1 other locations · NCT03901924

• Understanding diaphragm changes in patients awaiting lung transplants

  This study looks at how different breathing support methods affect the diaphragm in patients waiting for lung transplants to find ways to reduce diaphragm damage.

  Recruiting University Health Network, Toronto · Toronto · NCT03667027

• New ultrasound tool to measure lung strain in ICU patients

  This study is testing a new ultrasound tool to see if it can help doctors measure lung strain in ICU patients on ventilators to prevent lung injuries.

  Recruiting Centre hospitalier de l'Université de Montréal (CHUM) · Montreal, Quebec · NCT03405779

Related topics

Quick answers

How many Mechanical Ventilation Complication clinical trials are recruiting right now?

21, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 18 countries. The most sites are in China (3 trials), Italy (3 trials), Canada (2 trials), France (2 trials), United States (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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