Condition

Acute Respiratory Distress Syndrome (ARDS) clinical trials and research

• 28Clinical trials
• 12Countries

Newest Acute Respiratory Distress Syndrome (ARDS) clinical trials

All recruiting trials (28)

• Understanding immune patterns and ECMO strategies to help adults with severe ARDS

  This study tests how different immune and clinical patterns in adults with moderate-to-severe ARDS respond to ECMO and lung-protective care, aiming to improve outcomes.

  Recruiting at 16 sites Southeast University, China · Beijing, Beijing Municipality and 38 other locations · NCT07726940

• Optimal corticosteroid dosing for ARDS: short vs. prolonged therapy

  This trial tests different corticosteroid doses and treatment lengths to see which helps adults with ARDS who are on ventilators.

  Recruiting Phase 4 National Taiwan University Hospital · Taipei · NCT07711964

• Lateral positioning to optimize breathing in adults after abdominal surgery with ARDS

  This study tests whether lying on the left or right side helps improve lung function in adults who developed ARDS after abdominal surgery, using a bedside imaging test to watch ventilation and blood flow while changing positions.

  Recruiting Ruijin Hospital · Shanghai · NCT07669558

• Dexamethasone for sepsis-related ARDS in adults on ventilatory support

  This trial tests whether dexamethasone can help adults with sepsis-associated ARDS on ventilators recover better compared to placebo.

  Recruiting Phase 3 Southeast University, China · Nanjing, Jiangsu and 1 other locations · NCT07576660

• NIRS for EDResp: Which first helps hypoxemic adults best?

  This trial tests whether non-invasive ventilation with a mask (NIPPV) or high-flow nasal oxygen (HFNO) is more helpful for adults in the emergency department with acute hypoxemic respiratory failure.

  Recruiting at 9 sites Ohio State University · Tucson, Arizona and 8 other locations · NCT07558265

• Sodium bicarbonate with bedside electrical impedance tomography to map lung blood flow in ventilated adults

  This project will try whether a small sodium bicarbonate injection combined with bedside electrical impedance tomography can map lung blood flow in adults on mechanical ventilation, compared with hypertonic saline.

  Recruiting First Affiliated Hospital of Wannan Medical College · Wuhu, Anhui · NCT07542366

• How torso tilt and ventilator PEEP affect lung opening in ARDS

  This study will see if tilting the patient's torso and changing PEEP helps open more lung and improve breathing mechanics in adults with moderate to severe ARDS on a ventilator.

  Recruiting at 2 sites Zhongda Hospital · Nanjing, Jiangsu and 2 other locations · NCT07504731

• Spontaneous vs Controlled Mechanical Ventilation in Acute Hypoxemic Respiratory Failure

  This study tests whether allowing spontaneous breathing or using controlled ventilation is better for adults with acute hypoxemic respiratory failure who need invasive mechanical ventilation.

  Recruiting Oslo University Hospital · Oslo, Oslo · NCT07463885

• Safety and performance of the INBENTUS VERSATILE ventilator in adults on invasive mechanical ventilation

  This trial will test whether the INBENTUS VERSATILE ventilator is safe and performs well in adults who need assisted or controlled invasive mechanical ventilation and short-term weaning.

  Recruiting Iconic Solutions By Murcia SL · Murcia · NCT07432191

• Immune mechanisms in acute respiratory distress syndrome in ventilated ICU patients.

  This project will test whether patterns of inflammatory markers in blood match gene activity of lung immune cells in adults with ARDS who are on mechanical ventilation.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT07395076

• Treating sepsis-related acute lung injury with gut microbiota transplantation

  The team will test whether transplanting healthy gut bacteria can help adults with sepsis-related acute lung injury or ARDS recover better.

  Recruiting Phase 2/3 Shanghai University of Traditional Chinese Medicine · Shanghai, Putuo · NCT07342205

• Aprotinin inhaled for moderate to severe ARDS

  This trial tests inhaled aprotinin to see if it helps adults with moderate to severe ARDS in the ICU when added to standard care.

  Recruiting Phase 3 Fundacion del Hospital Nacional de Paraplejicos para la Investigacion y la Integracion · Ciudad Real, Ciudad Real · NCT07317050

• Lung and brain ultrasound to guide PEEP in adults with ARDS and acute brain injury

  This trial will test whether combining lung and transcranial ultrasound helps doctors choose the best PEEP level for adults on a ventilator with ARDS and acute brain injury.

  Recruiting George Papanicolaou Hospital · Thessaloniki · NCT07248995

• Using a paravertebral block during thoracic (VATS/RATS) surgery to reduce postoperative complications

  This study will try an intraoperative paravertebral block to see if it lowers postoperative complications in adults having VATS or RATS for lung or mediastinal procedures.

  Recruiting Tongji Hospital · Wuhan, Hubei · NCT07211529

• STSA-1002 injection for acute respiratory distress syndrome

  This trial will test whether STSA-1002 injection is safe and helps adults with acute respiratory distress syndrome caused by a respiratory viral infection breathe better.

  Recruiting at 15 sites Phase 3 Staidson (Beijing) Biopharmaceuticals Co., Ltd · Beijing, Beijing Municipality and 14 other locations · NCT07208591

• Measuring lung overinflation with electrical impedance tomography in ventilated COPD patients

  This project will use electrical impedance tomography to see if ventilated adults with moderate-to-severe COPD have uneven lung inflation or overdistension while on NIV or invasive ventilation.

  Recruiting Centre Hospitalier de la côte Basque · Bayonne, Centre Hospitalier de La Côte Basque · NCT07090460

• Prognostic model for Acute Respiratory Distress Syndrome using Electrical Impedance Tomography

  This study is trying to see if a new way of measuring lung function can help doctors predict how well patients with Acute Respiratory Distress Syndrome (ARDS) will do and tailor their treatment accordingly.

  Recruiting at 4 sites Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Guangzhou, Guangdong and 3 other locations · NCT06967207

• Using Electrical Impedance Tomography to Optimize Ventilator Settings in Patients with Severe Breathing Problems

  This study is trying to see if using a special imaging technique can help set ventilators better for patients with severe breathing problems like acute respiratory failure.

  Recruiting Mahidol University · Bangkok · NCT06936618

• Personalized PEEP and Prone Positioning in Severe ARDS

  This trial tests whether tailoring PEEP levels and using prone positioning with or without muscle relaxation can improve outcomes for adults with severe ARDS in the ICU.

  Recruiting at 29 sites Assistance Publique - Hôpitaux de Paris · Aix-en-Provence and 28 other locations · NCT06849570

• Investigating immune responses in viral pneumonia and ARDS

  This study looks at how certain immune cells behave in patients with viral pneumonia and ARDS to see if understanding them can help create better treatments.

  Recruiting University Hospital, Tours · Tours · NCT06720818

• Innovative therapies for Acute Respiratory Distress Syndrome

  This study is testing new treatments for adults in the hospital with Acute Respiratory Distress Syndrome to see if they can improve breathing and overall recovery compared to a placebo.

  Recruiting at 27 sites Phase 2 PPD Development, LP · Birmingham, Alabama and 40 other locations · NCT06703073

• Evaluating vilobelimab for treating Acute Respiratory Distress Syndrome

  This study is testing if vilobelimab can help hospitalized adults with Acute Respiratory Distress Syndrome feel better and improve their chances of recovery compared to a placebo.

  Recruiting at 28 sites Phase 2 PPD Development, LP · Birmingham, Alabama and 40 other locations · NCT06701682

• Evaluating a new treatment for Acute Respiratory Distress Syndrome

  This study is testing a new treatment called paridiprubart to see if it can help hospitalized adults with Acute Respiratory Distress Syndrome breathe better and improve their chances of recovery.

  Recruiting at 28 sites Phase 2 PPD Development, LP · Birmingham, Alabama and 40 other locations · NCT06701669

• Evaluating Bevacizumab for Acute Respiratory Distress Syndrome

  This study is testing whether a medication called bevacizumab can help hospitalized adults with Acute Respiratory Distress Syndrome breathe better and improve their chances of recovery.

  Recruiting at 28 sites Phase 2 PPD Development, LP · Birmingham, Alabama and 40 other locations · NCT06701656

• Effects of CPAP vs. High Flow Nasal Oxygen in ARDS Patients

  This study is testing whether using CPAP or high flow nasal oxygen helps people with acute respiratory distress syndrome breathe better and recover faster.

  Recruiting Hospital Clinic of Barcelona · Barcelona, Barcelona · NCT06694311

• Using diaphragmatic ultrasound to diagnose acute respiratory distress in emergency patients

  This study is testing if using diaphragmatic ultrasound can help doctors quickly diagnose pneumonia and other breathing problems in emergency patients who are having trouble breathing.

  Recruiting University Hospital, Montpellier · Nîmes, Gard and 1 other locations · NCT06650137

• Using Pirfenidone to prevent lung fibrosis in ARDS patients

  This study tests if the drug Pirfenidone can help prevent lung scarring in patients with Acute Respiratory Distress Syndrome (ARDS).

  Recruiting at 17 sites Phase 3 Università Vita-Salute San Raffaele · Milan, MI and 16 other locations · NCT05075161

• Assessing lung recruitment in ARDS patients using electrical impedance tomography

  This study is testing if a new method using electrical signals can help doctors see how well the lungs of patients with ARDS can be opened up for better breathing while they are on a ventilator.

  Recruiting at 3 sites Unity Health Toronto · São Paulo and 3 other locations · NCT04460859

Related topics

Quick answers

How many Acute Respiratory Distress Syndrome (ARDS) clinical trials are recruiting right now?

28, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 12 countries. The most sites are in China (9 trials), United States (5 trials), France (5 trials), Spain (4 trials), Italy (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 4, Phase 2: 4, Phase 4: 1, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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