Sponsor or institution
Clinical trials and research at Centre Hospitalier Universitaire de Nice
As of November 12, 2026, Find a Trial lists 119 clinical trials run by Centre Hospitalier Universitaire de Nice that are recruiting, at sites in 8 countries (most in France (119), French Guiana (1), Reunion (1)). By phase: Phase 2 (7), Phase 4 (5), Phase 3 (3), Phase 2/3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 119Clinical trials
- 8Countries
Newest trials
All recruiting trials (119)
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Capillary vs arterial blood gas analysis in COPD or APE patients with respiratory distress
This study tests whether a capillary blood gas test can replace the arterial test in adults with COPD flare or cardiogenic pulmonary edema who need non-invasive ventilation.
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BiP inhibitor BPR001-615 in colorectal adenocarcinoma
This study tests whether the BiP inhibitor BPR001-615 can affect cancer cells from colorectal adenocarcinoma, in patients who will have surgical removal of their tumor at Nice University Hospital.
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Three CT Signs of Nerve-Root Suffering in Low-Back Sciatica: How Often They Occur in Patients Referred for CT-Guided Nerve-Root Infiltration
This study tests whether three specific CT signs align with the nerve root causing symptoms in adults with low-back sciatica who are scheduled for CT-guided nerve-root infiltration.
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Innate immune cells in abdominal inflammation: observing their behavior in patients undergoing digestive surgery
This study tests how innate immune cells behave during inflammatory episodes by analyzing non-invasively collected abdominal fluid from adults having digestive surgery.
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Two anesthesia methods to keep the joint clear during shoulder arthroscopy
This trial tests whether inhaled sevoflurane vs. total intravenous anesthesia with propofol affects how well surgeons can see inside the shoulder during rotator cuff repair.
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Tracking Real-Life Myasthenia Gravis Symptoms in Patients on Rozanolixizumab
This observational study follows adults with generalized myasthenia gravis who are treated with Rozanolixizumab to see how their symptoms and fatigue change in real life.
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Measuring absolute brain blood flow and microcirculation with continuous thermodilution
We will use a catheter thermodilution method to measure brain blood flow and microvascular resistance in adults who had a successful mechanical thrombectomy for a middle cerebral artery stroke to see if we can obtain reliable absolute flow measurements.
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Intra-abdominal Pressure During Hernia Repair
This study tests perioperative abdominal pressure during open midline incisional hernia repair to see how pressure relates to outcomes in adults with moderate to large defects.
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Switching to ustekinumab for kids with Crohn's or ulcerative colitis who developed psoriasis after anti-TNF therapy
This study tests whether switching to ustekinumab helps children with inflammatory bowel disease who developed psoriasis while on anti-TNF drugs.
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Nerve ultrasound in people with Friedreich ataxia
This project uses routine peripheral nerve ultrasound to see if adults with genetically confirmed Friedreich ataxia have enlarged nerves.
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Methotrexate in hand osteoarthritis that hasn’t improved with usual treatments
This study tests whether methotrexate injections can help people with erosive hand OA who haven’t benefited from standard care, compared with placebo.
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See if the Modjaw digital jaw impressions help diagnose TMJ disc displacement
This interventional study tests whether Modjaw digital jaw recordings can help diagnose TMJ disc displacement in adults who already need an MRI for confirmation.
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Upadacitinib for adults with erosive mucosal lichen planus or lichen planopilaris
This trial tests whether upadacitinib can help adults with erosive mucosal lichen planus or lPP by comparing it to placebo.
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Adjusting guselkumab dosing schedules for adults with plaque psoriasis
This project will see if adults with plaque psoriasis who are doing well on guselkumab can safely have their injections spaced farther apart than nine weeks.
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Immune profile test for women with chronic pelvic pain and endometriosis
This study tests a functional immune test to see if immune profiles differ in women with chronic pelvic pain and endometriosis who aren’t responding to first-line treatments.
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Early ravulizumab for adults with myasthenic crisis in the ICU
This project will test whether giving ravulizumab early to adults with AChR-positive generalized myasthenia gravis who are in the ICU for a myasthenic crisis helps speed recovery.
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How common severe diabetes-related distress is in adults with type 2 diabetes at Nice University Hospital
This project will measure how common severe diabetes-related distress is and try to find what clinical, social, and lifestyle factors are linked to it in adults with type 2 diabetes treated at Nice University Hospital.
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Polypharmacy and Healthy Aging in People Living with HIV Aged 75 and Older
We’re looking to see how polypharmacy affects older adults with HIV and whether a geriatric approach can help tailor care.
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Upper-arm superficial vein thrombosis with catheter-related bloodstream infection in PICC or midline catheters
This study tests how often superficial vein thrombosis occurs during catheter-related bloodstream infections in people with PICC or midline catheters.
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Quality-of-life–guided red blood cell transfusions for people with refractory MDS or AML
We test whether using routine EQ-5D-5L quality-of-life scores to decide when to give red blood cell transfusions can safely reduce the number of transfusions for adults with refractory MDS or AML who are receiving only palliative care.
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Purinergic compounds for people with pseudoxanthoma elasticum
This trial will try purinergic compounds to see if restoring pyrophosphate-related signals can reduce tissue calcification in adults with genetically confirmed pseudoxanthoma elasticum.
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MatriDerm® nerve wrap to repair cut sensory nerves in the hand and fingers.
We will try wrapping a stitched hand or finger sensory nerve with MatriDerm® to see if it improves healing and reduces scarring for people aged 16–75 with traumatic nerve injuries.
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Attentional tunnelling in French dental and hospital practitioners
This project will test how common attentional tunnelling is and how it affects clinical decisions among French dental surgeons, university hospital practitioners, and interns.
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Using e-Bug classroom education to boost HPV vaccine consent in a middle school
This project tests whether using the e-Bug classroom education in a French middle school helps increase parental consent and HPV vaccination rates among eligible students during the 2023–2025 school campaigns.
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How liver failure, fibrosis, and low inorganic pyrophosphate contribute to artery calcification in people awaiting liver transplant
This study tests whether liver transplantation in people with chronic liver disease restores blood inorganic pyrophosphate and slows or stops arterial calcification.
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Interest in group-based health promotion among migrants and socially vulnerable adults in Nice
We will see if migrant and socially vulnerable adults who use the Médecins du Monde CASO in Nice are interested in group activities to promote health.
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Combination of Ritlecitinib and nbUVB for Vitiligo
This study tests if adding narrowband UVB to ritlecitinib helps treat vitiligo better than ritlecitinib alone in adults with non-segmental vitiligo.
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Digital biomarkers in people with radiologically isolated syndrome and MS who have normal neurological exams
This study will test whether digital biomarkers can tell apart people with radiologically isolated syndrome from multiple sclerosis patients who have a normal neurological exam.
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Bladder cancer and urinary microbiota in adults
This study looks to see if the bacteria in the bladder relate to bladder cancer in adults.
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Empagliflozin in very low eGFR with chronic kidney disease
This study tests whether empagliflozin can help people with advanced kidney disease and type 2 diabetes who have very low kidney function by reducing kidney protein leakage and potentially protecting kidney function.
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Corticosteroid-sparing efgartigimod for elderly AChR-positive generalized myasthenia gravis
This trial tests whether efgartigimod given IV or under the skin helps people 65 and older with AChR-positive generalized myasthenia gravis reduce their corticosteroid dose while keeping symptoms under control.
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Monitoring B cells and rituximab/anti‑rituximab antibodies during rituximab treatment for autoimmune disorders
This project will test whether checking B-cell counts and rituximab or anti-rituximab levels in the blood can help spot relapses in people with autoimmune cytopenia, connective tissue diseases, or vasculitis who are treated with rituximab.
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Omaveloxolone for swallowing problems in French people with Friedreich's ataxia
This project will test whether omaveloxolone (SKYCLARYS) improves swallowing in French people aged 16 and older with genetically confirmed Friedreich's ataxia who have used the drug for at least six months.
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Circulating pyrophosphate as a marker of vascular calcification in type 2 diabetes
This project will see if blood levels of inorganic pyrophosphate (PPi) can indicate peripheral vessel calcification in men aged 40–70 with type 2 diabetes.
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Pulsed-field ablation for persistent atrial fibrillation: a multicenter study with implantable monitor follow-up
Researchers test pulsed-field ablation to treat symptomatic persistent atrial fibrillation and track recurrences with an implantable monitor across multiple centers.
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Bacillus cereus invasive infections in preterm newborns in France
Researchers will use whole-genome sequencing on bacteria from preterm babies with Bacillus cereus infections to see if certain species or genes are linked to worse outcomes.
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Capillary (finger‑prick) lactate to predict severity after major multi‑injury
This project will test whether a quick capillary (finger‑prick) lactate test at the injury scene can help predict which adults with potentially serious multi‑injury will have poor outcomes.
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Morning versus evening flu vaccination for adults with chronic kidney failure
This trial will test whether giving the seasonal flu shot in the morning produces a stronger immune response than giving it in the evening for adults with advanced chronic kidney disease, people on dialysis, and kidney transplant recipients.
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Evaluating sleep quality in young cancer survivors
This study is trying to see how well young cancer survivors aged 15 to 24 sleep after their treatment and what factors might affect their sleep quality.
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Exploring sleep experiences in patients undergoing surgery
This study looks at how surgery and factors like anxiety and pain affect the sleep of patients before and after they go under general anesthesia.
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Examining mitochondrial function and metabolomic profiles in Alzheimer's disease
This study is testing if changes in energy production and certain substances in the blood can help us understand Alzheimer's disease better by comparing patients with Alzheimer's to those with other memory problems.
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Review of patients who had nail reconstruction after melanoma surgery
This study looks at how well different nail reconstruction methods work for patients who had melanoma surgery instead of having their nails amputated.
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Using Platelet-Rich Plasma to Treat Severe Dry Eye Syndrome
This study is testing if injecting Platelet-Rich Plasma into the tear glands can help people with severe dry eye syndrome produce more tears and feel better.
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Evaluating urinary dysfunction in patients with CANVAS
This study is trying to see how common urinary problems are in people with CANVAS and if these issues are linked to their neurological symptoms.
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Zilucoplan for French patients with anti‑AChR myasthenia gravis — three‑month outcomes
This project will try Zilucoplan (Zilbrysq) in French patients with anti‑AChR myasthenia gravis to see if muscle strength and quality of life improve over three months while tracking side effects.
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Program to enhance resilience in patients with cognitive disorders
This study is testing a program that uses therapy, mindfulness, and yoga to help people with mild cognitive disorders become more resilient and better cope with challenges.
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E-CANE: national remote therapeutic education workshops for adolescents and young adults with cancer
This program will try remote therapeutic education workshops to help adolescents and young adults in France living with cancer learn self-care skills and cope with treatment.
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Evaluating Bimekizumab for Early Treatment of Plaque Psoriasis
This study is testing a new treatment called bimekizumab to see if it works better than standard creams for people aged 18 to 45 with mild plaque psoriasis.
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Effects of Lifelong Physical Activity on Aging and Immune Function
This study is testing how staying active for a lifetime affects health and immune function in older adults over 55.
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Using transcriptomic analysis to diagnose mitochondrial diseases
This study is testing a new way to diagnose mitochondrial diseases by looking at gene activity in patients' cells to help those who haven't been diagnosed yet.
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Personalized physical activity program for bariatric surgery candidates
This study is testing a personalized exercise program for people with severe obesity who are about to have bariatric surgery to see if it helps reduce harmful chemicals in their blood and improves their health after losing weight.
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Virtual reality training to improve inhibitory control in older adults with cognitive disorders
This study tests whether using virtual reality training can help older adults with cognitive disorders improve their self-control skills.
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Fluid choice in severe diabetic ketoacidosis: balanced fluids vs saline
This trial tests whether balanced IV fluids (Ringer Lactate) help resolve severe diabetic ketoacidosis faster than standard isotonic saline in adults.
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Investigating long-term effects of COVID-19 through imaging and blood samples
This study is trying to find out how COVID-19 affects people in the long run by looking at brain scans and blood samples from those with ongoing symptoms and those who have fully recovered.
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Assessing Apremilast for Epidermolysis Bullosa Simplex in Children
This study is testing if a medication called Apremilast can help children with Epidermolysis Bullosa Simplex feel better and stay safe over 20 weeks.
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French bibliotherapy program for obsessive-compulsive symptoms
This study is testing a French self-help reading program to see if it can help people with obsessive-compulsive disorder feel better without changing their medication.
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Using brain stimulation to improve language function in primary progressive aphasia
This study is testing whether a type of brain stimulation can help improve language skills in people with primary progressive aphasia.
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Comparing Isotretinoin to Standard Care for Moderate Acne in Skin of Color
This study is testing whether the acne medication isotretinoin works better than standard treatments for young people with moderate acne and skin of color.
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Preparing elderly cancer patients for surgery
This study is testing a personalized training program to help older cancer patients get stronger and recover better before and after surgery.
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Paracetamol Use in ICU Patients: Does It Change Blood Pressure?
This study tests whether intravenous or oral paracetamol affects blood pressure in adults in the ICU who already have an arterial line.
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AI-guided personalized rituximab for membranous nephropathy
This trial will test whether an AI-guided approach to dosing rituximab improves remission in adults with PLA2R1-positive nephrotic membranous nephropathy.
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Investigating the role of inorganic pyrophosphate in children with chronic kidney disease
This study is testing how a substance called inorganic pyrophosphate affects blood vessel health in children with chronic kidney disease to see if it can help prevent related problems.
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Examining the relationship between oral and intestinal bacteria in patients with a specific gum disease
This study is trying to see how the bacteria in the mouth and gut affect people with a specific gum disease called Mucous Membrane Pemphigoid and whether these bacteria make their gum problems worse.
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Impact of GLP-1 Agonist on Fat Tissue in Bariatric Surgery Patients
This study is testing if a GLP-1 medication can change fat tissue and help people who are having bariatric surgery manage their weight and metabolic health better.
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Assessing cognitive impairment in young adults after ischemic stroke
This study is testing how an ischemic stroke affects thinking and memory in young adults aged 18-45 over time.
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Location of motor cortex stimulation electrodes in chronic neuropathic pain
This study tests how the placement of motor cortex stimulation electrodes relates to response in adults with chronic neuropathic pain who already have implanted stimulation and a postoperative scan.
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Using Functional Proprioceptive Stimulation to aid recovery after stroke
This study is testing if a new type of stimulation can help people recovering from a stroke improve their movement and balance faster.
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Topical treatment for superficial basal cell carcinoma
This study is testing a new ointment to see if it can safely treat superficial basal cell carcinoma in adults when the cancer is not on the face or scalp.
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Evaluating causes of isolated rectal bleeding in newborns
This study is trying to find out how often cow's milk protein allergies cause rectal bleeding in newborns who are hospitalized for this issue.
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Understanding the progression of Facioscapulohumeral Muscular Dystrophy Type 2
This study is trying to learn more about how Facioscapulohumeral Muscular Dystrophy Type 2 affects people and how it progresses over time by tracking symptoms in patients with this condition.
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Evaluating Cholestyramine's Effect on Obese Women Before Bariatric Surgery
This study is testing if a medication called cholestyramine can help reduce harmful chemicals in the bodies of obese women before they have weight loss surgery.
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Testing lipoprotein levels in patients with lymphedema
This study is testing if people with lymphedema have higher levels of a certain type of fat in their blood that could increase their risk of heart problems.
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Examining fat tissue in the knee and thigh muscles of patients with osteoarthritis
This study looks at fat tissue in the knees and thigh muscles of people with knee osteoarthritis to see how it affects muscle strength and the progression of the condition.
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Detecting Alzheimer's and mood disorders through voice analysis
This study is testing whether analyzing voice patterns can help detect Alzheimer's and mood disorders without needing invasive tests like spinal taps or scans.
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Using inelastic compression to treat edema after leg surgery
This study is testing if a new type of compression can help reduce swelling in the legs after surgery for people with lymphedema.
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Rifampicin-containing regimens for Cutibacterium acnes prosthetic joint infections
This trial tests whether adding rifampicin to amoxicillin or moxifloxacin can improve outcomes for adults with C. acnes prosthetic joint infections treated with one- or two-stage revisions.
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Using machine learning to predict success in weaning patients off mechanical ventilation
This study is testing a new way to use machine learning to see if it can help doctors predict which patients in critical care will successfully breathe on their own after being on a ventilator.
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Gait Improvement With Spinal Cord Stimulation in Postoperative Back Pain Patients
This study tests whether spinal cord stimulation can improve walking and reduce pain in adults with failed back surgery syndrome who have ongoing chronic leg and back pain.
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Hypnosis on your smartphone to reduce postoperative pain after appendicitis with peritonitis
This project tests whether short hypnosis videos on a smartphone can help adults reduce pain and anxiety after emergency laparoscopic surgery for appendicitis with generalized peritonitis.
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Comparing METHOXYFLURANE and Virtual Reality to Standard Pain Management for Shoulder Dislocation
This study is testing if using METHOXYFLURANE and virtual reality can help relieve pain better than standard methods for people with shoulder dislocations.
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Electrical stimulation for chronic upper limb pain relief
This study is testing if electrical stimulation of certain nerves can help people with chronic pain in their arms feel better when other treatments haven’t worked.
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Measuring blood flow in diabetic patients using a new method
This study is testing a new, quicker way to measure blood flow in diabetic patients to see if it can help spot peripheral arterial disease more easily than the usual method.
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Evaluating eye movement diagnostics for neurological conditions
This study is testing if a new eye movement test can help find hidden neurological problems in people with multiple sclerosis and related conditions.
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Using AI to improve lung cancer screening
This study is testing whether using artificial intelligence to analyze chest scans can help improve lung cancer screening for patients by making it more accurate and reducing unnecessary follow-ups.
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Same Day Ambulatory Appendectomy
This study tests whether doing appendectomies on the same day without an overnight hospital stay can safely help people with uncomplicated appendicitis feel better and improve their overall care experience.
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Testing immune responses to predict melanoma treatment outcomes
This study is testing if measuring certain immune signals in patients with advanced melanoma can help predict how well they will respond to a combination treatment of nivolumab and ipilimumab.
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Metabolism in the Lymphatic Niche of CLL
This study looks at how the lymphatic environment affects metabolism in people with chronic lymphocytic leukemia (CLL) to see if it influences disease behavior.
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Thromboxane A2 and Osteoarthritis
Researchers are testing whether thromboxane A2 affects cartilage cells and osteoarthritis in humans and animals to see if it could help explain cartilage health and point toward new therapies.
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Assessing IL-17 levels in patients with spondyloarthritis
This study is testing if measuring IL-17 levels in patients with active spondyloarthritis can help doctors choose the best biological treatment after other medications haven't worked.
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Investigating how glucose metabolism affects dendritic cell movement in psoriasis
This study is testing how glucose metabolism affects the movement of certain immune cells in people with moderate to severe psoriasis compared to those without the condition.
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Observational study on Radiologically Isolated Syndrome and Multiple Sclerosis
This study looks at people with Radiologically Isolated Syndrome to see how their brain changes over time and if these changes might lead to Multiple Sclerosis.
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Adapted physical activity for recovery after stem cell transplantation
This study tests if doing six sessions of adapted physical activity at home can help people recovering from stem cell transplants lose weight and improve their quality of life.
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Home-based personalized training and video consultations for mitochondrial myopathy patients
This study tests whether a personalized training program and video consultations can help people with mitochondrial myopathy improve their health and quality of life.
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Personalized physical activity for elderly muscle health
This study is testing if personalized exercise plans can help older adults maintain their muscle health better than standard exercise or no exercise at all.
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Understanding tumor metabolism in melanoma and immunotherapy resistance
This study is trying to see how changes in melanoma tumor cells affect their response to immunotherapy, hoping to find better treatment options for patients.
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Comparing CPX-351 to Intensive Chemotherapy for Acute Myeloid Leukemia
This study is testing if a new treatment called CPX-351 can help older patients with a tough form of leukemia do better than traditional chemotherapy.
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Investigating heart function's role in weaning from mechanical ventilation
This study is testing how heart function affects the ability of critically ill patients on mechanical ventilation to breathe on their own without developing lung problems.
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Examining the oral bacteria in elderly people with and without Alzheimer's disease
This study is trying to see if the types of bacteria in the mouths of older adults can help us understand more about Alzheimer's disease by comparing those with the condition to those without it.
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Analyzing Inflammatory Biomarkers for Diagnosing CNS Autoimmune Diseases
This study is testing if certain markers in blood and spinal fluid can help doctors more accurately diagnose multiple sclerosis and other similar brain conditions.
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Using video feedback to improve walking rehabilitation after a stroke
This study tests if using video feedback can help people who have had a stroke walk better and regain their independence compared to traditional rehab methods.
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Using high-flow oxygen therapy for migraine relief in the emergency department
This study is testing if high-flow oxygen therapy can help people in the emergency department feel better during a migraine attack and reduce their time spent in the ER.
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Does crunching sound affect eating pleasure in older adults who are frail or malnourished?
This study tests whether crunchy textures in cookies can enhance eating enjoyment for adults 65 and older who are frail, malnourished, or toothless.
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Using multi-omics to diagnose mitochondrial diseases
This study is testing a new way to diagnose mitochondrial diseases by looking closely at RNA from muscle and skin samples of patients who have had unclear genetic test results.
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Using a glucose measurement system in intensive care for patients with shock
This study is testing a new glucose monitoring system to see if it can help make checking blood sugar easier and more comfortable for patients in intensive care who are dealing with septic shock.
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Using PPI to Treat Pseudoxanthoma Elasticum
This study is testing if taking a supplement called pyrophosphate can help adults with Pseudoxanthoma Elasticum reduce harmful calcification in their bodies.
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AiCR: Using AI to predict outcomes in Cardiac Arrest
Aims to test an AI algorithm that predicts mortality and recurrence risk for patients admitted to ICU with cardiac arrest.
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Examining the incidence of COVID-19 infections
This study is trying to see how common COVID-19 infections are and how air pollution affects people's immune responses and health during the reopening phase after lockdowns.
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Who can correctly use the scrotal pump for an inflatable penile prosthesis
This study looks at which patients can successfully use the scrotal pump after penile prosthesis implantation.
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Chilblain-like skin changes during COVID-19 infection
This observational study looks at people with COVID-19 who develop skin lesions that look like chilblains to see what these sores have in common and what they might mean for the disease overall.
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National collection of membranous nephropathy cases in France
This project tests a one-year national collection of membranous nephropathy cases in France to learn about incidence, antibodies, outcomes, and risk factors.
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Understanding empathy in schizophrenia through brain activity markers
This study is trying to see how brain activity relates to empathy in people with schizophrenia to help improve understanding and treatment of the condition.
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From Immune System and Kidney Cell Damage in Nephrotic Syndrome
We’re testing how immune system changes and podocyte (kidney cell) damage relate to first episodes of nephrotic syndrome in both kids and adults.
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Evaluating Amiloride for Preventing Migraine Aura
This study is testing if the medication amiloride can help prevent migraine aura in people who experience this type of migraine.
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Cutaneous and Mucosal Signs in Children with Neurofibromatosis Type 2
This study looks for skin and mucous membrane signs in kids under 15 who have neurofibromatosis type 2 to see if these features can help with early detection when other symptoms are present.
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Using PET-CT scans to predict response to anti-PD-1 therapy in melanoma patients
This study is testing if PET-CT scans can help predict how well melanoma patients will respond to a specific immunotherapy treatment.
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Nice HIV Cohort Follow-Up
This project follows people with HIV who have scheduled outpatient visits to see how their health changes over time using routine medical records.
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Observing cancer cases in the Sud-Provence-Alpes-Côte d'Azur region
This study is setting up a cancer tracking system in the Sud-Provence-Alpes-Côte d'Azur region to gather important information about cancer cases to help improve prevention and treatment strategies.
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Relevance of Peripheral Cells in CMML
This study looks at how peripheral blood cells relate to chronic myelomonocytic leukemia and how they might help understand the disease in patients being treated at participating centers.
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Understanding how Azacitidine resistance develops in certain blood cancers
This study looks at how some patients with high-risk blood cancers stop responding to the treatment Azacitidine to help find better ways to fight these diseases.
Quick answers
How many clinical trials run by Centre Hospitalier Universitaire de Nice are recruiting right now?
119, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 8 countries. The most sites are in France (119 trials), French Guiana (1 trial), Reunion (1 trial), Belgium (1 trial), Italy (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 7, Phase 4: 5, Phase 3: 3, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.