Immune profile test for women with chronic pelvic pain and endometriosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The study uses an immune profiling approach by measuring Th1, Th2, Th17, and Treg cytokines after non-specific functional cell stimulation to identify immune imbalances in women with chronic pelvic pain and endometriosis. It is conducted in a real-world setting among patients aged 18 to 40 who are on long-term hormone therapy and have recent imaging results. The trial is interventional and focuses on a blood-based immune test to characterize the immune response rather than a traditional drug or device therapy. Primary results will describe whether this functional immune test can reliably characterize immune profiles associated with CPP and endometriosis in this population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Aged between 18 and 40;
2. Under continuous hormone treatment for at least 6 months;
3. Imaging less than 12 months old: either normal or showing endometriosis and/or adenomyosis lesions, excluding any other abnormalities that could explain the PCOS;
4. Affiliation with the French Social Security system;
5. Signature of informed consent.

Exclusion Criteria:

1. Pregnant or breastfeeding women;
2. Autoimmune disease;
3. History of cancer within the last 5 years or currently undergoing treatment;
4. Current infectious syndrome;
5. Person under guardianship or conservatorship.

Where it's running

• CHU Nice - Hôpital de l'Archet 2
  Nice, Alpes-Maritimes, France Recruiting

Study contacts

• Study coordinator: Pierre-Alexis GAUCI, MD
• Email: gauci.pa@chu-nice.fr
• Phone: 04 92 03 61 90

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Tele-rehabilitation for chronic pelvic pain in endometriosis

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• Postoperative Pain Trajectories After Endometriosis Surgery

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  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT07882498

• Imaging endometriosis with a special PET tracer in adult women

  This study tests whether a PET/CT scan using [18F]AlF-FAPI-74 can help detect endometriosis lesions in women who are planning laparoscopy.

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• Fiber supplement for digestive symptoms in endometriosis

  A fiber-based supplement is being tested to see if it is safe and helps with gut and vaginal microbiomes and digestive symptoms in women with endometriosis.

  Recruiting LOAM Science · San Francisco, California · NCT07875062

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.