Location of motor cortex stimulation electrodes in chronic neuropathic pain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study analyzes the brain regions activated by epidural motor cortex stimulation in adults with chronic neuropathic refractory pain. The researchers will examine the myeloarchitectonic and functional characteristics of these areas and explore how these patterns relate to treatment response. The aim is to better understand mechanisms behind motor cortex stimulation and identify potential predictors of who benefits. No intervention beyond existing stimulation is performed, and results will be based on postoperative imaging and clinical data. The study is conducted at CHU Nice in France and is sponsored by Centre Hospitalier Universitaire de Nice.

Why it matters

Who can join: the full rules

Inclusion Criteria

* adults
* patient implanted with a motor cortical stimulation system for chronic neuropathic refractory pain,
* patient with available postoperative scanner

Exclusion Criteria: None

Where it's running

• Chu Nice
  Nice, Alpes Maritimes, France Recruiting

Study contacts

• Principal investigator: Petru ISAN — Centre Hospitalier Universitaire de Nice
• Study coordinator: Petru ISAN
• Email: isan.p@chu-nice.fr
• Phone: 0642619135

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Neuropathic Pain Severity in Lumbar Spinal Stenosis and Its Link to Radiology

  This study will test how severe neuropathic pain is in adults with lumbar spinal stenosis and see if it relates to MRI findings and other clinical features.

  Recruiting Marmara University · Istanbul, Istanbul · NCT07855445

• Virtual Reality-Based Hypnotherapy to Help Pain, Sleep, and Mood in Spinal Cord Injury

  Adults with spinal cord injury will try adding short VR-based hypnotherapy sessions to their standard physiotherapy to see if it reduces pain and improves sleep and mood.

  Recruiting Istanbul Physical Medicine Rehabilitation Training and Research Hospital · Istanbul, Istanbul · NCT07846410

• Extended-release Pregabalin for nerve pain from diabetes or shingles

  This phase 3 study tests an extended-release form of pregabalin to see if it reduces nerve-pain symptoms in adults with diabetic neuropathy or postherpetic neuralgia.

  Recruiting at 15 sites Phase 3 Brainfarma Industria Química e Farmacêutica S/A · Salvador, Estado de Bahia and 14 other locations · NCT07712913

• High-Intensity Peripheral Magnetic Stimulation for Traumatic Nerve Injury

  This study tests whether adding high-intensity peripheral magnetic stimulation to a structured exercise program can reduce pain and improve function for adults with a traumatic peripheral nerve injury.

  Recruiting Gaziler Physical Medicine and Rehabilitation Education and Research Hospital · Ankara · NCT07705490

• Hematological clues and how patients respond to nerve blocks for neuropathic pain

  This study looks at blood inflammation markers to see if they relate to how well people with neuropathic pain respond to sympathetic nerve blocks.

  Recruiting Ankara City Hospital Bilkent · Ankara, Cankaya · NCT07596823

• Cord plasma eye drops to treat neuropathic corneal pain

  This trial will test whether cord plasma eye drops can reduce long-lasting nerve-related corneal pain in people with evidence of corneal nerve damage.

  Recruiting Singapore Eye Research Institute · Singapore, Singapore · NCT07566806

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.