Examining the incidence of COVID-19 infections

Study of the Incidence of SARS-CoV-2 Infection in the Alpes-Maritimes Department by Analysis of the Specific Humoral and Cellular Response During Deconfinement

Not applicable Interventional Centre Hospitalier Universitaire de Nice · NCT04429594

This study is trying to see how common COVID-19 infections are and how air pollution affects people's immune responses and health during the reopening phase after lockdowns.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment1000 (estimated)
Ages18 Years and up
SexAll
SponsorCentre Hospitalier Universitaire de Nice Academic / other
Locations1 site (Nice)
Trial IDNCT04429594 on ClinicalTrials.gov

What this trial studies

This observational cohort study aims to determine the prevalence and incidence of COVID-19 infections using serological and PCR tests among approximately 1000 subjects during the deconfinement phase. Participants will serve as their own controls, comparing their immune responses and epigenetic markers before and after exposure to air pollutants as economic activities resume. The study will also assess the impact of these pollutants on various health outcomes, including infectious and autoimmune events.

Who should consider this trial

Good fit: Ideal candidates for this study are adults who have been exposed to the public since May 11, 2020, and are informed about the study.

Not a fit: Patients who are under legal protection or unable to participate in clinical studies due to health regulations will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the relationship between air pollution and COVID-19 infection rates, potentially guiding public health policies.

How similar studies have performed: While studies on the impact of air pollution on health are common, this specific approach to linking it with COVID-19 incidence is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Any major subject, voluntary, exposed to the public from 11 May 2020 informed of the study by partner institutions (Departmental Council 06), affiliated to a social security scheme,

Exclusion Criteria:

* Subject protected by law under tutorship or guardianship, or who cannot participate in a clinical study under the terms of Article L. 1121-16 of the French Public Health Code

Where this trial is running

Nice

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Coronavirus Infections
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.