Observational study on Radiologically Isolated Syndrome and Multiple Sclerosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on individuals with Radiologically Isolated Syndrome (RIS), characterized by white matter abnormalities detected through MRI without prior neurological symptoms. The study aims to track the progression of these abnormalities and identify factors that may predict the development of clinical demyelinating events. Participants will undergo regular monitoring to assess any changes in their neurological status over time. The study is part of a larger effort to understand the natural history of RIS and its potential progression to Multiple Sclerosis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* white matter T2 lesions suggestive of demyelination
* asymptomatic
* normal neurological exam

Exclusion Criteria:

* abnormal neurological exam,
* suspicion of another disease explaining MRI lesions.

Where it's running

• Nice University Hospital
  Nice, France Recruiting

Study contacts

• Study coordinator: Christine LEBNRUN-FRENAY
• Email: lebrun-frenay.c@chu-nice.fr
• Phone: 33 4 92 03 41 26

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.