Using e-Bug classroom education to boost HPV vaccine consent in a middle school

Pilot Observational Comparative Study Evaluating the Impact of the e-Bug Educational Programme on Parental Consent and HPV Vaccination Coverage During the National School-Based Vaccination Campaign in a Middle School in the Alpes-Maritimes

Observational Centre Hospitalier Universitaire de Nice · NCT07266857

This project tests whether using the e-Bug classroom education in a French middle school helps increase parental consent and HPV vaccination rates among eligible students during the 2023–2025 school campaigns.

Quick facts

Study typeObservational
Enrollment11000 (estimated)
SexAll
SponsorCentre Hospitalier Universitaire de Nice Academic / other
Locations1 site (Nice, Alpes Maritimes)
Trial IDNCT07266857 on ClinicalTrials.gov

What this trial studies

This is a non-interventional observational pilot using aggregated, anonymised vaccination data collected routinely by ARS PACA for the 2023–2024 and 2024–2025 national school-based HPV vaccination campaigns. The pilot school in the Alpes-Maritimes department had teachers and the school nurse already using e-Bug resources as part of routine health education; no new intervention was introduced or modified for research purposes. Aggregated vaccination consent and uptake from the pilot school are compared with departmental-level outcomes to describe whether upstream classroom education may be associated with differences in parental consent and vaccination coverage. No individual-level data or direct recruitment of students or families occurred for this analysis.

Who should consider this trial

Good fit: The analysis concerns aggregated data for middle school students eligible for routine school-based HPV vaccination (early adolescents) at the pilot school and in the Alpes-Maritimes department.

Not a fit: Students outside the routine vaccination age range, those already up-to-date with HPV vaccination, or students at schools that did not use e-Bug would not see direct benefit from this pilot's findings.

Why it matters

Potential benefit: If successful, this approach could increase parental consent and HPV vaccine uptake among middle school students, supporting broader school-based education as a tool to improve vaccination coverage.

How similar studies have performed: Previous school-based education and informational campaigns have sometimes increased parental consent or vaccine uptake, but results across studies have been mixed and often modest.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* No individual participants are enrolled. The study uses only aggregated, anonymised vaccination data routinely collected by ARS PACA

Exclusion Criteria:

* Not applicable. No individual-level inclusion or exclusion criteria are defined, as no participants are enrolled.

Where this trial is running

Nice, Alpes Maritimes

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Papillomavirus InfectionPapillomavirus VaccinesVaccination Coveage
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.