Three CT Signs of Nerve-Root Suffering in Low-Back Sciatica: How Often They Occur in Patients Referred for CT-Guided Nerve-Root Infiltration

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a retrospective, single-center observational study conducted at Nice University Hospital. It reviews pre-infiltration CT scans to see how often three signs (nerve-root size asymmetry, peri-radicular infiltration, and spontaneous root hyperdensity) appear near the clinically suspected nerve root. The goal is to determine if these signs correlate with the painful root and could help guide treatment planning for CT-guided procedures. Current data include 104 patients and 105 infiltrations, with about 16.8% showing all three signs and 38.6% showing at least two signs. The study analyzes scans from January 30, 2024, to July 11, 2024, with a target of 400 participants.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult (\>= 18 years)
* Low-back sciatica / radicular pain with a systematized distribution
* Referred for CT-guided foraminal or peri-radicular infiltration at Pasteur 2 Hospital (Nice) between 30 Jan 2024 and 11 Jul 2024.
* Available and interpretable pre-infiltration planning CT

Exclusion Criteria:

* Planning CT missing or not interpretable
* Missing data on the three studied signs
* Radicular pain of tumoral, infectious or recent traumatic origin
* Spinal history precluding analysis of the studied root

Where it's running

• Chu Nice
  Nice, Alpes Maritimes, France Recruiting

Study contacts

• Study coordinator: kevin desalos
• Email: kevindesalos@gmail.com
• Phone: 06 87 63 05 74

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.