Bacillus cereus invasive infections in preterm newborns in France

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational project sequences the genomes of Bacillus cereus group strains isolated from invasive infections in preterm neonates hospitalized in France. The team performed whole-genome sequencing on 40 clinical isolates and screened for known virulence genes. Clinical data from the affected neonates were collected and combined with genomic findings to look for factors associated with death or severe disease. The goal is to provide accurate species-level identification and a virulome profile of strains involved in these infections.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Premature newborn (i.e born before 37 last menstrual periods) with invasive infection caused by B. cereus (strains isolated from blood culture and cerebrsopinal fluid)

Exclusion Criteria:

* None

Where it's running

• Chu Nice
  Nice, Alpes Maritimes, France Recruiting
• CHU lille
  Lille, France Recruiting
• AP-HM Marseille
  Marseille, France Recruiting
• CHU Nantes
  Nantes, France Recruiting
• CHU Nîmes
  Nîmes, France Recruiting
• AP-HP Hôpital Robert Debré
  Paris, France Recruiting

Study contacts

• Study coordinator: Raymond Ruimy
• Email: ruimy.r@chu-nice.fr
• Phone: 04.92.03.62.20

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.