Personalized physical activity program for bariatric surgery candidates
Persistent Organic Pollutants and Mechanical Discharge: Limiting the Impact of Bariatric Surgery Through Personalized Adapted Physical Activity
This study is testing a personalized exercise program for people with severe obesity who are about to have bariatric surgery to see if it helps reduce harmful chemicals in their blood and improves their health after losing weight.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 55 Years |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire de Nice Academic / other |
| Locations | 1 site (Nice) |
| Trial ID | NCT06597617 on ClinicalTrials.gov |
What this trial studies
This study focuses on patients with severe obesity who are scheduled for bariatric surgery. It aims to investigate the effects of personalized adapted physical activity on the release of Persistent Organic Pollutants (POPs) into the bloodstream, which can have adverse health effects post-surgery. The intervention includes aerobic and strength training tailored to the individual needs of the participants. The study seeks to understand how these activities can mitigate the negative impacts of massive weight loss on metabolism and neuromuscular function.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-55 who are scheduled for bariatric surgery and engage in limited physical activity.
Not a fit: Patients who are pregnant, breastfeeding, or have contraindications to physical activity will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance recovery and overall health outcomes for patients undergoing bariatric surgery.
How similar studies have performed: While the specific approach of addressing POPs in bariatric surgery candidates may be novel, similar studies have shown that tailored physical activity can improve outcomes in obesity management.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patient (18-55 years) * Patient scheduled for bariatric surgery * Patient practicing a leisure-time physical activity \< 8 hours of moderate intensity per week or \< 4 hours of high intensity per week * Presence of effective contraception (hormonal or mechanical) Exclusion Criteria: * Patient already involved in another experimental study * Pregnant (urine pregnancy test) or breast-feeding women * Patient in a particular situation deemed incompatible with the study by the investigator * Patients from outside the Alpes-Maritimes and Var departments * Patient having received antibiotic treatment during the 3 months preceding the first stool collection * Presence of a contraindication to adapted physical activity * Presence of a contraindication to neurostimulation
Where this trial is running
Nice
- CHU de Nice — Nice, France (Recruiting)
Study contacts
- Principal investigator: Nicolas CHEVALIER, Pr — Centre Hospitalier Universitaire de Nice
- Study coordinator: Nicolas CHEVALIER, Pr
- Email: chevalier.n@chu-nice.fr
- Phone: 04 92 03 67 55
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.