Personalized physical activity program for bariatric surgery candidates
Official title: Persistent Organic Pollutants and Mechanical Discharge: Limiting the Impact of Bariatric Surgery Through Personalized Adapted Physical Activity
Run by Centre Hospitalier Universitaire de Nice · NCT06597617 · Data updated 2026-11-12
This study is testing a personalized exercise program for people with severe obesity who are about to have bariatric surgery to see if it helps reduce harmful chemicals in their blood and improves their health after losing weight.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 55 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Centre Hospitalier Universitaire de Nice Academic / other |
| Locations | 1 site (Nice) |
| Status | Recruiting |
| Started | June 2025 |
| Main results expected | June 2028 |
| Study ends | October 2028 |
| Registry record updated | March 25, 2025 |
| Trial ID | NCT06597617 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18-55 who are scheduled for bariatric surgery and engage in limited physical activity.
✕Probably not a fit
Patients who are pregnant, breastfeeding, or have contraindications to physical activity will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on patients with severe obesity who are scheduled for bariatric surgery. It aims to investigate the effects of personalized adapted physical activity on the release of Persistent Organic Pollutants (POPs) into the bloodstream, which can have adverse health effects post-surgery. The intervention includes aerobic and strength training tailored to the individual needs of the participants. The study seeks to understand how these activities can mitigate the negative impacts of massive weight loss on metabolism and neuromuscular function.
Why it matters
Potential benefit: If successful, this approach could enhance recovery and overall health outcomes for patients undergoing bariatric surgery.
How similar studies have gone: While the specific approach of addressing POPs in bariatric surgery candidates may be novel, similar studies have shown that tailored physical activity can improve outcomes in obesity management.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patient (18-55 years) * Patient scheduled for bariatric surgery * Patient practicing a leisure-time physical activity \< 8 hours of moderate intensity per week or \< 4 hours of high intensity per week * Presence of effective contraception (hormonal or mechanical) Exclusion Criteria: * Patient already involved in another experimental study * Pregnant (urine pregnancy test) or breast-feeding women * Patient in a particular situation deemed incompatible with the study by the investigator * Patients from outside the Alpes-Maritimes and Var departments * Patient having received antibiotic treatment during the 3 months preceding the first stool collection * Presence of a contraindication to adapted physical activity * Presence of a contraindication to neurostimulation
Where it's running
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CHU de Nice
Nice, France Recruiting
Study contacts
- Principal investigator: Nicolas CHEVALIER, Pr — Centre Hospitalier Universitaire de Nice
- Study coordinator: Nicolas CHEVALIER, Pr
- Email: chevalier.n@chu-nice.fr
- Phone: 04 92 03 67 55
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Stress response with desflurane versus opioid-free TIVA during weight-loss surgery
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This study is testing whether customizing the lengths of certain parts of gastric bypass surgery can help people lose more weight and improve their health compared to standard lengths.
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Education to improve drinking habits and oral hygiene for people having bariatric surgery
This project will test three types of patient education—a custom website, clinician-led sessions, or free dental-hygiene samples—to see which best helps people having bariatric surgery improve drinking habits and oral care.
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High-intensity interval exercise to support brain activity and weight maintenance
This trial will test whether a 12-week high-intensity interval training (HIIT) program changes brain activity and helps with weight maintenance in adults 18–70, including people who regained weight after bariatric surgery.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.