Personalized physical activity for elderly muscle health
Official title: Biological & Fonctional Signatures for Muscle Failures, Aged People & Personalized Physical Activity : BioFaSt MAPPA
Run by Centre Hospitalier Universitaire de Nice · NCT05343286 · Data updated 2026-11-12
This study is testing if personalized exercise plans can help older adults maintain their muscle health better than standard exercise or no exercise at all.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 60 Years and up |
| Sex | All |
| Enrollment | 900 (estimated) |
| Sponsor | Centre Hospitalier Universitaire de Nice Academic / other |
| Locations | 1 site (Nice) |
| Status | Recruiting |
| Started | April 29, 2022 |
| Main results expected | April 15, 2027 |
| Study ends | April 15, 2028 |
| Registry record updated | December 3, 2025 |
| Trial ID | NCT05343286 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are seniors aged 60 and older who are capable of providing informed consent and can participate in a physical activity program.
✕Probably not a fit
Patients with neurocognitive disorders or other physical or cognitive pathologies that prevent them from participating in the physical activity protocol may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to explore the effects of personalized physical activity management on muscle failure in elderly individuals. It will involve 900 seniors divided into three groups: one receiving adapted and personalized physical activity, another receiving adapted physical activity, and a control group with no physical activity. The study will analyze biological signatures related to muscle failure and utilize machine learning techniques for data interpretation. Participants will engage in a 3-month intervention, with a total study duration of 5 years.
Why it matters
Potential benefit: If successful, this study could lead to tailored physical activity programs that significantly improve muscle health and overall well-being in the elderly.
How similar studies have gone: While the approach of personalized physical activity is gaining traction, this specific study's methodology and focus on biological signatures in elderly muscle failure is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age greater than or equal to 60 years * Affiliated patient or beneficiary of a social security scheme * Patient having signed a prior informed consent. Exclusion criteria * Neurocognitive disorder preventing the expression of informed consent * Patients protected by law under guardianship or curatorship, or who cannot participate in a clinical study under Article L. 1121-16 of the French Public Health Code * Presence of a physical or cognitive pathology preventing the performance of the adapted physical activity protocol over 3 months.
Where it's running
-
CHU de Nice
Nice, France Recruiting
Study contacts
- Principal investigator: Olivier GUERIN, PU-PH — geriatric Department
- Study coordinator: Olivier GUERIN, PU-PH
- Email: guerin.o@chu-nice.fr
- Phone: 0492034194
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.