Assessing IL-17 levels in patients with spondyloarthritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the feasibility of measuring IL-17 cytokine levels in patients with active spondyloarthritis (axSpA) who require biological treatment after failing at least two non-steroidal anti-inflammatory drugs (NSAIDs). By stimulating immune cells and analyzing cytokine responses, the study seeks to develop a tool that could assist clinicians in selecting the most appropriate biologic therapy for these patients. The study focuses on patients meeting the ASAS criteria for spondyloarthritis and aims to address the lack of validated biomarkers in this area.

Why it matters

Who can join: the full rules

Inclusion criteria

* Patients with spondyloarthritis meeting the ASAS criteria
* Patients who were to benefit from the implementation of a biological treatment after failure of at least two NSAIDs.
* Patients having an active disease defined by a Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) higher than four,

Exclusion criteria

* No predominant axial manifestation,
* Having received a previous biological treatment
* Patients presenting contraindication to the implementation of these treatments.

Where it's running

• CHU de NICE
  Nice, France Recruiting

Study contacts

• Study coordinator: Christian ROUX
• Email: roux.c2@chu-nice.fr
• Phone: +33492035491

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.