Examining fat tissue in the knee and thigh muscles of patients with osteoarthritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the characteristics of Hoffa adipose tissue and intramuscular adipose tissue in the quadriceps muscle of patients diagnosed with knee osteoarthritis. It aims to understand the relationship between skeletal muscle characteristics, particularly quadriceps weakness, and the progression of knee osteoarthritis. By analyzing tissue samples obtained through biopsy, the study seeks to uncover the mechanisms by which muscle and adipose tissue may influence the pathophysiology of osteoarthritis. The findings could provide insights into the role of muscle health in managing knee osteoarthritis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patient, aged between 40 and 85 years
* Patient having a confirmed diagnosis of knee ostheoarthritis
* Patient undergoing a surgery for a total knee prosthesis for knee ostheoarthritis

Exclusion Criteria:

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Where it's running

• Nice University Hospital
  Nice, France Recruiting

Study contacts

• Study coordinator: Christian ROUX, PUPH
• Email: roux.c2@chu-nice.fr
• Phone: 0492035491

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.